Our Daily Vites L-Methylfolate 7.5 mg / 7500 mcg Maximum Strength Active Folate, 5-MTHF, Filler Free, Gluten Free, Non-GMO, Vegetarian Capsules 90 Count (3 Month Supply) (90)

FOLATE IN THIS FORM IS IDEAL and not a casual topic with ramifications in short and long term consequences over one's lifetime. Medical community's and literature's use of folate and folic acid interchangably only adds to confusion w/possible dangerous (and possibly heartbreaking) consequences.If you are planning to get pregnant, avoid folic acid and only take this, unless you have a confirmation of your MTHFR status. (Folic acid is often responsible for miscarriages, esp multiple ones, and a reason why OBGYNs often tell women to take a baby aspirin daily as a somewhat ignorant work-aroind to thin blood.)I found out that I have MTHFR genetic anomaly while treated for lyme (one good thing about it) and need this form of Folate to help optimize my methelation cycle to deal with it, which also includes elimination of fortified food and taking a methelated form of B12. (I think that everyone should be tested for it at birth, tbh, since it has many short and long-term manifestations and consequences.) Antibiotic use did, apparently, enough damage to my intestines and I ended up with RD a year later (auto immune response to molecular mimicry, a discovery still a mystery to vast majority of rheumatologists whose first step in treatment is prescription for methotrexate).Rheumatoid Disease sufferers are forced into taking (cookie cutter approach by rheumatologists) this drug, so the Folate supplement is a must-have because this chemo drug shuts down your body's folate production, already decreased through the auto-immune disease - and one of many reasons why many feel worse rather than better and has devastating effect on common anemia, taki g it to extreme unless countered with correct folate supplementation. If you have RA/RD, understand that it is likely a result of leaky gut/molecular mimicry, and healing it is the only way to improve your situation rather than taking stronger and stronger drugs like biologics to 'treat' RD by suppressing symptoms/immune system and sideffects alone may be deadly. Methotrexate almost finished me off with a red blood cell level of a leukemia patient by the time I deliberately discontinued its use, simultaneously noticing that I felt better if I did not eat (NOT a workable solution). Although I told the rheumatologist that I have MTHFR, never once did he mention body's folate shut off side effect! Thank God I was already aware of MTHFR needs, but still my maintenance dose was insufficient to combat drug's side effect [Btw, I got off it, follow Clint Paddison protocol of plant based diet, steadily boosted/restored my blood cells without blood transfusions with (YAY!) with help of Mega Foods Iron supplement (@4 times normal dose over last year) and went from complete cripple-like debilitated agony, weighing nothing and contemplating unmentionable way out to a functional person with just a few select areas of disability and continue to improve. Understand that RD affects heart, lungs, bones, cognitive function including balance, deforms joits, causes anemia, deprssion and reduces one's life span by average of 10-15 years - all this on top of excruciating pain in multiple organs at once. It is nothing like osteoarthritis and is an auto-immune condition vs joint wear and tear via friction over years.BOTTOM LINE: IF you take Deplin, have MTHFR, are treated with any drugs which affect your body's ability to produce Folate, have miscarried, deal with leaky gut/molecular mimicry/auto-immune diseases - do get this little easily absorbed capsule with a nicely high dose and get tested for MTHFR via a simple blood test (blood draw or, for kids, a mouth swab) or 23andMe raw data processed by third party app . If you are or know someone on psychiatric meds, please encourage them to get tested for MTHFR and also read up on how gut health contributes to mental issues. For those who do not know, Deplin is just a 50 mg dose of folate and prescribed by psychiatrists, but as a 'food supplement' is usually ineligible for insurance. It's $$$. Those taking it often find that they not only need fewer or lower dose scripts, but some no longer need them. FOLATE (not folic acid) and B12 combination plays a critical role in methelation cycle and a requirement for serotonin and dopamine production, body's ability to get rid of waste including medications staying in one's body. Those w/one of MTHFR genetic anomalies (40% of population) cannot process common cheap shelf stable forms of both - folic acid and cyanocobalamin. Folic Acid is literally shoved our throats in fortified flour, banned in 156 countries and, because it's quicker absorbed in the intestines though useless to one with this condition, prevents FOLATE in food from getting in. This is one of reasons why many who test negative for gluten intolerance feel much better after cutting out fortified foods, many of which are baked goods - not because of wheat.WRT Vit B12 (a related topic!) in cyanocobalamin form gives false higher B12 blood readings (pouring oil on water), is peed out and deprives a body of a critical vitamin. In worst cases, lack of it is dangerous in itself - pernitious anemia (why so many vegans and vegetarians are actually walking sick) and/or in extreme cases show schizophrenia-like symptoms often misdiagnosed as such because B12 levels are rarely checked, misread as adequate (already mentioned). Too many doctors are ignorant or dismissive of fairly recent understanding of MTHFR gene function. I recall one case when a "schitzophrenic" patient was saved by a NURSE who checked for her B12 levels and after a few B12 shots (i.e. correct form of B) the hopeless individual was released a couple days later in a normal state. Excess of non-absorbable B12 over one's lifetime may result in Front-lobal dementia.I realize that it is a long endorsement for a little capsule, but all these (still simplified) points barely begin scratching the surface on the topics of MTHFR anomalies, leaky gut, Rheumatoid Disease, autism implications, endometriosis, many auto-immune illnesses like Fibromyalgia, MS, Scleroderma, multiple miscarriages, crohns disease, celiac, psychiatric issues including substance abuse, thyroud and heart problems among many others - all tied to one's ability to get a crucial set of vitamins.You can learn more about MTHFR on mthfr.net, started by an MD whose own health issues drove him to research more about it, genetic inplications, work-arounds and consequences. In process he dedicated his career to this topic and is a go-to source, but you can also find many videos on line explaining these common anomalies. With regard to that - if you don't have it - yay! If you do or can't get tested - play it safe and use methelated forms of B12 and Folate, avoiding the bad forms.I hope that this gives you more tools and perhaps prompts you to look at your own (or your family's) history/situation and see if there is more to explore in healing and improving what ails you, beyond a simple sypplement. Again, keep in mind, if you take this as an MTHFR person and continue to consume fortified foods, you MAY NOT GET FULL BENEFIT. Peace.

I'm so grateful that L- Methyl is available via Amazon at this affordable price. The quality is great. I know it's working because I see and feel the difference in my health. For those of us with the MTHFR gene mutation this is a God send. Thank you!

Really feeling the effects early on. I'm bipolar and this has worked with other supplements and my medication to stabilize my mood and give me natural energy throughout the day. I had derealization, disassociation, and brain fog for nearly 8 and a half years but I read about l methylfolate and a gene mutation so figured I'd try it and it's only been 4 days and already feeling back in reality. This stuff really works. Highly recommended

My psychiatrist recommended supplementing L-methylfolate, my genetic testing came back as a "moderate" converter of folic acid to methylfolate. The pills are small and tasteless but not sure I would notice if they were making a difference with my depression or not.

After my husband learned he had a mutated gene that prevents you from absorbing folic acid and his doctor prescribed him deplin. Just recently our insurance stopped coverage of this item so I turned to the internet and found this brand which also has a micro capsule. The small capsule makes it very easy for people that have difficulty swallowing pills to take, such as my husband does. He has been using this brand for a month or two now and there seems to be no adjustment or difference from the previous prescription so, so far all is good.

I use this because I have the MTHFR defect that causes difficulty processing B vitamins. I have used this brand for at least 2 years. Because my body no longer believes it is starving for something it lacked, I have lost 130 lbs after my doctor also added back other essential B vitamins like this one.

These did not work for me at all. They made my left arm itch immediately and gave me a pretty annoying headache. I take another GMO Free organic multi-vitamin each day and really hoped these would work for me but they didn’t. I’ve taken a B complete vitamin and never had any adverse reaction to those. And I’ve taken L Methyl -folate before and it helped my focus this brand did not. I really wanted these to help my anxiety but these seemed to make me more nervous feeling. I definitely felt something it just wasn’t what I wanted, didn’t seem like my metabolism was processing these well at all. Every body handles things differently so who knows. I’m guessing I need to try the prescription L-MethylFolate. I searched for a customer service email but couldn’t find a way to contact them, I really wanted them to reach out to me, in my return request I left a note with my reasoning for the return and nobody got back to me, I wanted to ask a few questions about the product, so that’s why I left 1⭐️! I wanted help from the seller, and nope that didn’t happen. Maybe I just looked in the wrong place, but communication shouldn’t be that hard. I do not recommend these for anxiety or folate deficiency.

My daughter's doctor tested my daughter and found her to be deficient. I found this supplement at the health food store but could not afford it. I looked on Amazon and found this product. Perfect!