What are the ingredients?

Propylene Glycol, Glycerine, Benzyl Alcohol, Dextrose, Hydroxypropyl Cellulose, Purified Water, Potassium Iodide, Lactoperoxidase, Glucose Oxidase, Lysoxyme, Lactoferrin. My dog had a problem with chronic ear infections. The vet told me to use this daily to prevent future ear infections. It has worked well. I put it in a glass of warm water to heat it up, so my dog doesn't mind getting the drops any more. Hope this helps.

Can you insert this ointment right into the ear canal?

Apply liberally in DIRTY ear to fill canal. Gently massage and work into infected area. Wipe to remove excess. Treat once a day for 7 days, 14 for chronic. Flush ear after treatment.

Can this be used on guinea pigs?

I would strongly advise you first find an animal vet and ask them first about using that on a guinea pig. That also includes dog vets - ask a good honest vet FIRST for good advice.

What is the difference between this (the ear solution without hydrocortisone) and the otic ear treatment without hydrocortisone?

This is from their website, hope it helps. Hydrocortisone or Non-Hydrocortisone: Which Zymox is Better for My Dog? Hydrocortisone is a glucocorticoid steroid with anti-inflammatory actions. It acts on the auto-immune responses of the body to lessen symptoms like swelling, redness, and itchiness. Zymox Otic with hydrocortisone can be very beneficial if your dog is experiencing discomfort caused by painful swelling and itchiness due to chronic inflammation. Corticosteroids are very useful in certain circumstances but come with a long list of adverse side effects. Overuse of hydrocortisone can cause excessive thirst, weight gain, liver failure and even behavioral changes. It is best to use with caution. Zymox with hydrocortisone is also detrimental when used for a fungal infection. So, before administering Zymox Otic HC, be sure that your dog’s outer ear infection is caused by bacteria or virus and not fungi. Zymox Otic without hydrocortisone is safe to use in most situations. Zymox Otic non-HC is best to use if you are not exactly sure of the type of ear infection that your dog has. It is also recommended for canines with a history of liver and kidney disease. If your dog has open sores in its ear/s, it is better to use Zymox Otic non-HC.

Otic Enzymatic Ear Solution For Dogs And Cats To Soothe

Description

🐶🐱 Clear ears, happy pets—because they deserve the best care!

ENZYMATIC POWERHOUSE - LP3 Enzyme System targets germs, fungi & yeast for fast relief
GENTLE YET EFFECTIVE - No-sting formula soothes painful ear infections without irritation
SENSITIVE PET FRIENDLY - Hydrocortisone-free, perfect for pets with delicate skin
TRUSTED BY PET PARENTS - 4.6⭐ from 1,376 reviews—ear care that actually works
STRESS FREE APPLICATION - No pre-cleaning needed—just fill and let it work its magic

Zymox Otic Enzymatic Ear Solution is a hydrocortisone-free, enzyme-powered treatment designed to soothe and clear ear infections in dogs and cats. Its gentle, no-sting formula works without pre-cleaning, targeting germs, fungi, and yeast to promote healthy ears for pets of all ages.

Specifications

ASIN	B01LGSYOGK
ASIN	B01LGSYOGK
Best Sellers Rank	#13,742 in Pet Supplies ( See Top 100 in Pet Supplies ) #67 in Dog Ear Care
Brand Name	Zymox
Customer Reviews	4.6 4.6 out of 5 stars (1,381)
Date First Available	September 3, 2016
Date First Available	September 3, 2016
Directions	For external use only. Shake bottle well before use. Apply to uncleaned ear, filling ear canal. Gently massage and work into area. Wipe to remove excess. Allow pet to shake head. Apply once daily for seven (7) days.
Is Discontinued By Manufacturer	No
Item Dimensions LxWxH	3 x 2 x 1 inches
Item Package Dimensions L x W x H	3.94 x 1.89 x 1.26 inches
Item Weight	0.08 Pounds
Item model number	RZES0125WO
Item model number	RZES0125WO
Manufacturer	Pet King Brands
Manufacturer	Pet King Brands
Product Dimensions	3 x 2 x 1 inches; 1.28 ounces
Size	1.25 fl oz
Specific Uses for Product	Ears
Target Audience Keyword	dogs, pets

Reviews

L**K

IT WORKS!!!

This is a regular part of my dog's first aid kit - wouldn't be without it. Works well, great price, easy to use, and nips ear discomfort/infections in the bud before they go too far.

8.03.2026

R**O

It’s safe for your pets

Great item, it really got in his ear and cleaned it out

6.04.2026

S**E

Great product

This product is great! My dog's ear was red, and itchy. This relieved it with just one application. Still using it daily to clear up any remaining issue, but it definitely works.

21.03.2026

S**N

What's most important to know about this product

Use this item regularly to keep pets ears clean. Works best when it's used regularly to keep ears clearn

2.08.2025

S**S

Good

Works better than anything else ive tried

2.03.2026

D**N

Hydrocortisone Allergy led me to this product

Want to write a review in hopes that it helps out another dog parent. My dog is prone to ear infections from yeast. I was looking for a product to treat at home and came across zymox otic hydrocortisone 1% it had great reviews so I was excited to try it. Day 1 started out great, was super easy to apply and appeared to be legitimately working for my dog as the smell from her infection was way less strong and less irritated. 4 hours later she continued shaking her head a ton so I was questioning when that goes away but think thats kind of normal. But than she tryed to itch it alot and noticed more redness it appeared to leave a noticeable mild rash I had done some more research and it appeared there are side effects to using steroids and some dogs are allergic to hydrocortisone and one of the side effects are rash!! I was disappointed as I found that out cause I really felt it would work outside of giving her a rash that caused more itching. But than I found this version of zymox that is hydrocortisone free and decided to try that as a last resort and am on day 4 and there is no rash and this product is really working!! Annoyed that I'm $40 down now by buying two bottles of this stuff but hoping this will save me way more money in the future. I guess what I'm trying to say is if you have a pup that you know is more skin sensitive and the infection is mild I recommend trying the hydrocortisone free version first!! It's hard to pinpoint what ingredients your dog might be sensitive too but hope this helps somebody!!

30.03.2023

C**R

Works great to keep my dogs ears clean

Good cleaning solution for my doodles ears. Easy to squirt in and seems to help with ear odor and cleanliness.

9.01.2026

L**S

Don't work that great for the money spent

Don't work that great

26.12.2025

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Otic Enzymatic Ear Solution for Dogs and Cats to Soothe Ear Infections Without Hydrocortisone, 1.25oz

Description

Specifications

Reviews

Common Questions