--- product_id: 763645 title: "Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets" brand: "prilosec" price: "$72.32" currency: USD in_stock: true reviews_count: 8 category: "Prilosec" url: https://www.desertcart.us/products/763645-prilosec-otc-omeprazole-delayed-release-20mg-acid-reducer-treats-frequent store_origin: US region: United States of America --- # 24-hour relief duration #1 doctor recommended 20mg delayed-release Omeprazole Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets **Brand:** prilosec **Price:** $72.32 **Availability:** ✅ In Stock ## Summary > 🔥 Stop heartburn before it starts — 24-hour relief you can count on! ⏳ ## Quick Answers - **What is this?** Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets by prilosec - **How much does it cost?** $72.32 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/763645-prilosec-otc-omeprazole-delayed-release-20mg-acid-reducer-treats-frequent) ## Best For - prilosec enthusiasts ## Why This Product - Trusted prilosec brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Trusted by Experts:** Recommended by doctors and gastroenterologists for over 15 years—join millions who rely on it. - • **All-Day Heartburn Blocker:** One pill each morning delivers 24 hours of powerful acid control—no more midday flare-ups. - • **FSA/HSA Eligible & Gentle:** Safe for daily use as directed, gentle on your stomach, and eligible for flexible spending accounts. - • **Convenient 42-Count Supply:** A month and a half of consistent relief in one easy-to-carry blister pack. - • **Clinically Proven Omeprazole:** 20mg delayed-release formula targets acid production at the source for lasting relief. ## Overview Prilosec OTC delivers clinically proven, 24-hour heartburn relief with a single 20mg delayed-release Omeprazole pill each morning. Unlike antacids that only neutralize acid temporarily, Prilosec prevents excess acid production, providing long-lasting comfort. Trusted by doctors for over 15 years, this 42-tablet pack offers a convenient, reliable solution for frequent heartburn sufferers seeking to reclaim their day and night without discomfort. ## Description With one Prilosec OTC pill each morning, block your heartburn for a full 24 hours.* Heartburn happens when stomach acid refluxes into the esophagus. Prilosec OTC’s delayed-release formula helps it pass through the tough stomach acid, preventing excess acid production to block frequent heartburn.* Some other heartburn relief treatments only neutralize the stomach acid after it’s already been produced and provide shorter relief (less than 24 hours). Prilosec OTC is the #1 Doctor and Gastroenterologist recommended frequent heartburn medicine for over 15 years.† Prilosec OTC’s active ingredient, 20 mg of delayed released omeprazole, works to fight heartburn differently from treatments like acid controllers/H2s or antacids. Omeprazole blocks heartburn for a full 24 hours after taking one pill each morning.* Omeprazole is a proton pump inhibitor (PPI) and PPIs are a powerful class of frequent heartburn medicines. PPIs block heartburn by preventing excess acid production…something that antacids just can’t do. With 1 Prilosec OTC pill each morning, block heartburn for 24 hours,* unlike antacids which last only 1-3 hours. * Zero heartburn is possible with Prilosec OTC. Not for immediate relief. Take one pill per day as directed to treat frequent heartburn. May take 1 to 4 days for full effect. Compared to how antacids for heartburn. Use all heartburn medications as directed. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Not for immediate relief. † IQVIA ProVoice Survey, 2005 – 2022. ^ Check with insurance provider Review: Helped immensely with my acid reflux, very reliable brand - This is the generic to omeprazole and it's helped immensely with my acid reflux since I stopped taking the omeprazole from my doctor. I just didn't get a refill. 😅 But i take it every day and don't have stomach problems or chest pain, it's been great. It tastes fine and it's very effective. Review: awesome - Awesome Seller, Great Packaging, Received On-Time, Excellent Super Great Product, Great Pricing, Described to a "T”!! Will buy again and Again from this Seller!! Great Job. Thank You for Going out of the way for what you have done to get them here!!!! I will follow your STORE!! Thanks. ## Features - TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week - With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours - PREVENT EXCESS ACID PRODUCTION for heartburn relief that lasts for 24 HOURS.* Starts working on DAY 1* - CONTAINS ACTIVE INGREDIENT OMEPRAZOLE delayed-release 20mg, an acid reducer that provides long-lasting, heartburn relief* - #1 DOCTOR and GASTROENTEROLOGIST RECOMMENDED frequent heartburn medicine for over 15 years. FSA and HSA eligible ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0000AN9L7 | | Active Ingredients | 20 mg of Omeprazole | | Additional Features | Long-Lasting | | Age Range Description | Adult | | Best Sellers Rank | #568 in Health & Household ( See Top 100 in Health & Household ) #7 in Antacids #74 in Sales & Deals | | Brand | Prilosec | | Brand Name | Prilosec | | Container Type | Box | | Customer Reviews | 4.7 out of 5 stars 19,551 Reviews | | Dosage Form | Tablets | | Flavor | Regular | | Global Trade Identification Number | 00030772198292, 00037000359074, 10037000359071 | | Item Dimensions | 2.32 x 4.75 x 3.7 inches | | Item Form | Tablet | | Item Nype Name | antacids tablet | | Item dimensions L x W x H | 2.32 x 4.75 x 3.7 inches | | Manufacturer | Procter & Gamble | | Manufacturer Part Number | OTC | | Model Name | Prilosec Otc Omeprazole Delayed Release Acid Reducer Frequent Heartburn Relief Tablets 1 | | Model Number | OTC | | Net Content Count | 42 Count | | Net Content Weight | 2.4 Pounds | | Number of Items | 1 | | Package Type Name | Blister | | Product Benefits | Acidity Relief | | Specific Uses For Product | Heartburn | | Target Audience | Unisex-Adults | | Target Use Body Part | Stomach | | UPC | 030772198292 037000359074 030772224359 785923031163 | | Unit Count | 42 Count | ## Product Details - **Active Ingredients:** 20 mg of Omeprazole - **Brand:** Prilosec - **Item dimensions L x W x H:** 2.32 x 4.75 x 3.7 inches - **Product Benefits:** Acidity Relief - **Specific Uses For Product:** Heartburn ## Images ![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 1](https://m.media-amazon.com/images/I/81Ieek7yUoL.jpg) ![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 2](https://m.media-amazon.com/images/I/81DmwjMa0rL.jpg) ![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 3](https://m.media-amazon.com/images/I/71xic3kTTNL.jpg) ![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 4](https://m.media-amazon.com/images/I/71dmEW3MjjL.jpg) ![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 5](https://m.media-amazon.com/images/I/71qo+hJ1v7L.jpg) ## Available Options This product comes in different **Size, Flavor** options. ## Questions & Answers **Q: How to take Prilosec OTC?** A: Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor. See label for detailed directions. **Q: When to take Prilosec OTC?** A: Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor. **Q: Can I take Prilosec OTC at night?** A: It is recommended take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor. **Q: What is the dose of Prilosec OTC?** A: Each Prilosec OTC tablet contains 20mg of Omeprazole. Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor **Q: What happens if I miss a Prilosec OTC dose?** A: If you miss a day, just continue your treatment on the next day. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Helped immensely with my acid reflux, very reliable brand *by T***R on April 14, 2026* This is the generic to omeprazole and it's helped immensely with my acid reflux since I stopped taking the omeprazole from my doctor. I just didn't get a refill. 😅 But i take it every day and don't have stomach problems or chest pain, it's been great. It tastes fine and it's very effective. ### ⭐⭐⭐⭐⭐ awesome *by M***R on January 11, 2026* Awesome Seller, Great Packaging, Received On-Time, Excellent Super Great Product, Great Pricing, Described to a "T”!! Will buy again and Again from this Seller!! Great Job. Thank You for Going out of the way for what you have done to get them here!!!! I will follow your STORE!! Thanks. ### ⭐⭐⭐⭐⭐ Excellent Relief for Frequent Heartburn *by J***N on September 10, 2025* Prilosec OTC has been a lifesaver for me when it comes to managing frequent heartburn. The 20mg delayed-release tablets work steadily and provide all-day and all-night relief, which makes such a big difference in my daily comfort. I like that one tablet a day is all it takes, and it starts working quickly without any hassle. The 42-count package is also very convenient, giving me a good supply that lasts for weeks. Since I started using it, I’ve noticed a huge improvement in my sleep and overall quality of life, because I’m not waking up with discomfort anymore. It’s easy to take, gentle on the stomach, and reliable in preventing that burning sensation. I really appreciate that it tackles the issue at the source instead of just masking the symptoms. This product has become an essential part of my routine, and I would highly recommend it to anyone dealing with regular heartburn. ## Frequently Bought Together - Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct - Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/763645-prilosec-otc-omeprazole-delayed-release-20mg-acid-reducer-treats-frequent](https://www.desertcart.us/products/763645-prilosec-otc-omeprazole-delayed-release-20mg-acid-reducer-treats-frequent) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-05-17*