--- product_id: 763645 title: "- OTC Frequent Heartburn Medicine and Acid Reducer Treatment with Omeprazole, Proton Pump Inhibitor - PPI, 42 Tablets (20 mg)" brand: "prilosec" price: "$40.10" currency: USD in_stock: true reviews_count: 8 category: "Prilosec" url: https://www.desertcart.us/products/763645-otc-frequent-heartburn-medicine-and-acid-reducer-treatment-with-omeprazole store_origin: US region: United States of America --- # 24-hour acid control 20mg delayed-release Omeprazole #1 doctor recommended - OTC Frequent Heartburn Medicine and Acid Reducer Treatment with Omeprazole, Proton Pump Inhibitor - PPI, 42 Tablets (20 mg) **Brand:** prilosec **Price:** $40.10 **Availability:** ✅ In Stock ## Summary > 🔥 Beat heartburn all day, every day with Prilosec OTC! ## Quick Answers - **What is this?** - OTC Frequent Heartburn Medicine and Acid Reducer Treatment with Omeprazole, Proton Pump Inhibitor - PPI, 42 Tablets (20 mg) by prilosec - **How much does it cost?** $40.10 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/763645-otc-frequent-heartburn-medicine-and-acid-reducer-treatment-with-omeprazole) ## Best For - prilosec enthusiasts ## Why This Product - Trusted prilosec brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **All-Day Heartburn Defense:** One pill each morning blocks heartburn for a full 24 hours, unlike short-lived antacids. - • **FSA/HSA Eligible & Convenient:** 42 tablets in a compact box, perfect for busy professionals managing wellness. - • **Fast-Acting Relief That Lasts:** Starts working on day 1 to reduce acid flare-ups 2+ times a week. - • **Powerful Proton Pump Inhibitor:** Contains 20mg delayed-release Omeprazole to prevent excess acid production at the source. - • **Clinically Trusted for 15+ Years:** Top choice of doctors and gastroenterologists for frequent heartburn relief. ## Overview Prilosec OTC delivers 24-hour relief from frequent heartburn with a single daily 20mg delayed-release Omeprazole tablet. Unlike antacids that only neutralize acid temporarily, this proton pump inhibitor prevents excess acid production, providing long-lasting comfort. Trusted by doctors for over 15 years, it’s the go-to solution for adults experiencing heartburn flare-ups twice or more weekly. ## Description With one Prilosec OTC pill each morning, block your heartburn for a full 24 hours.* Heartburn happens when stomach acid refluxes into the esophagus. Prilosec OTC’s delayed-release formula helps it pass through the tough stomach acid, preventing excess acid production to block frequent heartburn.* Some other heartburn relief treatments only neutralize the stomach acid after it’s already been produced and provide shorter relief (less than 24 hours). Prilosec OTC is the #1 Doctor and Gastroenterologist recommended frequent heartburn medicine for over 15 years.† Prilosec OTC’s active ingredient, 20 mg of delayed released omeprazole, works to fight heartburn differently from treatments like acid controllers/H2s or antacids. Omeprazole blocks heartburn for a full 24 hours after taking one pill each morning.* Omeprazole is a proton pump inhibitor (PPI) and PPIs are a powerful class of frequent heartburn medicines. PPIs block heartburn by preventing excess acid production…something that antacids just can’t do. With 1 Prilosec OTC pill each morning, block heartburn for 24 hours,* unlike antacids which last only 1-3 hours. * Zero heartburn is possible with Prilosec OTC. Not for immediate relief. Take one pill per day as directed to treat frequent heartburn. May take 1 to 4 days for full effect. Compared to how antacids for heartburn. Use all heartburn medications as directed. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Not for immediate relief. † IQVIA ProVoice Survey, 2005 – 2022. ^ Check with insurance provider Review: Prilosec OTC, Omeprazole 20mg, Heartburn Medicine, Acid Reflux Medicine, 24 Hour Relief, 42 T - effectiveness and help lot for heartburn Review: awesome - Awesome Seller, Great Packaging, Received On-Time, Excellent Super Great Product, Great Pricing, Described to a "T”!! Will buy again and Again from this Seller!! Great Job. Thank You for Going out of the way for what you have done to get them here!!!! I will follow your STORE!! Thanks. ## Features - TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week - With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours - PREVENT EXCESS ACID PRODUCTION for heartburn relief that lasts for 24 HOURS.* Starts working on DAY 1* - CONTAINS ACTIVE INGREDIENT OMEPRAZOLE delayed-release 20mg, an acid reducer that provides long-lasting, heartburn relief* - #1 DOCTOR and GASTROENTEROLOGIST RECOMMENDED frequent heartburn medicine for over 15 years. FSA and HSA eligible ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0000AN9L7 | | Active Ingredients | 20 mg of Omeprazole | | Additional Features | Long-Lasting | | Age Range Description | Adult | | Best Sellers Rank | #563 in Health & Household ( See Top 100 in Health & Household ) #7 in Antacids #74 in Sales & Deals | | Brand | Prilosec | | Brand Name | Prilosec | | Container Type | Box | | Customer Reviews | 4.7 out of 5 stars 19,574 Reviews | | Dosage Form | Tablets | | Flavor | Regular | | Global Trade Identification Number | 00030772198292, 00037000359074, 10037000359071 | | Item Dimensions | 2.32 x 4.75 x 3.7 inches | | Item Form | Tablet | | Item Nype Name | antacids tablet | | Item dimensions L x W x H | 2.32 x 4.75 x 3.7 inches | | Manufacturer | Procter & Gamble | | Manufacturer Part Number | OTC | | Model Name | Prilosec Otc Omeprazole Delayed Release Acid Reducer Frequent Heartburn Relief Tablets 1 | | Model Number | OTC | | Net Content Count | 42 Count | | Net Content Weight | 2.4 Pounds | | Number of Items | 1 | | Package Type Name | Blister | | Product Benefits | Acidity Relief | | Specific Uses For Product | Heartburn | | Target Audience | Unisex-Adults | | Target Use Body Part | Stomach | | UPC | 030772198292 037000359074 030772224359 785923031163 | | Unit Count | 42.0 Count | ## Product Details - **Active Ingredients:** 20 mg of Omeprazole - **Brand:** Prilosec - **Item dimensions L x W x H:** 2.32 x 4.75 x 3.7 inches - **Product Benefits:** Acidity Relief - **Specific Uses For Product:** Heartburn ## Images ![- OTC Frequent Heartburn Medicine and Acid Reducer Treatment with Omeprazole, Proton Pump Inhibitor - PPI, 42 Tablets (20 mg) - Image 1](https://m.media-amazon.com/images/I/81Ieek7yUoL.jpg) ## Available Options This product comes in different **Size, Flavor** options. ## Questions & Answers **Q: How to take Prilosec OTC?** A: Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor. See label for detailed directions. **Q: When to take Prilosec OTC?** A: Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor. **Q: Can I take Prilosec OTC at night?** A: It is recommended take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor. **Q: What is the dose of Prilosec OTC?** A: Each Prilosec OTC tablet contains 20mg of Omeprazole. Take one pill a day with a glass of water before eating in the morning for 14 days. You may repeat this 14-day treatment every four months, or as directed by your doctor **Q: What happens if I miss a Prilosec OTC dose?** A: If you miss a day, just continue your treatment on the next day. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Prilosec OTC, Omeprazole 20mg, Heartburn Medicine, Acid Reflux Medicine, 24 Hour Relief, 42 T *by H***E on May 21, 2026* effectiveness and help lot for heartburn ### ⭐⭐⭐⭐⭐ awesome *by M***R on January 11, 2026* Awesome Seller, Great Packaging, Received On-Time, Excellent Super Great Product, Great Pricing, Described to a "T”!! Will buy again and Again from this Seller!! Great Job. Thank You for Going out of the way for what you have done to get them here!!!! I will follow your STORE!! Thanks. ### ⭐⭐⭐⭐⭐ Helped immensely with my acid reflux, very reliable brand *by T***R on April 14, 2026* This is the generic to omeprazole and it's helped immensely with my acid reflux since I stopped taking the omeprazole from my doctor. I just didn't get a refill. 😅 But i take it every day and don't have stomach problems or chest pain, it's been great. It tastes fine and it's very effective. ## Frequently Bought Together - Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct - Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/763645-otc-frequent-heartburn-medicine-and-acid-reducer-treatment-with-omeprazole](https://www.desertcart.us/products/763645-otc-frequent-heartburn-medicine-and-acid-reducer-treatment-with-omeprazole) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-07-12*