---
product_id: 762677543
title: "Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract (Large / 90 Day Avg. Supply)"
brand: "vetsmart formulas"
price: "$380.16"
currency: USD
in_stock: true
reviews_count: 6
category: "Vet Smart Formulas"
url: https://www.desertcart.us/products/762677543-critical-immune-defense-for-dogs-and-cats-supports-normal-cell
store_origin: US
region: United States of America
---

# 4 medicinal mushrooms blend eco-friendly large jar immune system booster Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract (Large / 90 Day Avg. Supply)

**Brand:** vetsmart formulas
**Price:** $380.16
**Availability:** ✅ In Stock

## Summary

> 🛡️ Elevate your pet’s vitality with nature’s immune elite!

## Quick Answers

- **What is this?** Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract (Large / 90 Day Avg. Supply) by vetsmart formulas
- **How much does it cost?** $380.16 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/762677543-critical-immune-defense-for-dogs-and-cats-supports-normal-cell)

## Best For

- vetsmart formulas enthusiasts

## Why This Product

- Trusted vetsmart formulas brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **All-Age Pet Wellness:** Perfect for puppies, seniors, dogs & cats of every breed
- • **Mushroom Powerhouse Blend:** Turkey Tail, Reishi, Shiitake & Maitake for cellular vitality
- • **Long-Lasting 90-Day Supply:** One large jar replaces 3 smaller ones for convenience & sustainability
- • **Veterinarian-Formulated Immunity:** Scientifically crafted to strengthen natural defenses
- • **Inflammation Defense & Resilience:** Supports healthy inflammatory response & cellular protection

## Overview

Critical Immune Defense is a premium, vet-developed supplement featuring a potent blend of four medicinal mushrooms and patented white turmeric extract. Designed for dogs and cats of all ages, it supports normal cell growth, reduces inflammation, and boosts immune resilience. Packaged in an eco-friendly 19 oz jar, it offers a convenient 90-day supply to keep your pet healthy and active, backed by rigorous quality standards and natural ingredients.

## Description

desertcart.com : Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract (Large / 90 Day Avg. Supply) : Pet Supplies

Review: I AM BACK TO BUY MORE! - Update: We have only one bottle of powder left, so I'm reordering. I still have my grand-dog, Gus, on this supplement, and he is still running and chasing the ball during play time. My son is a firm believer in this product, and so am I. I have my younger female dogs on it as well. It is costly, but when I consider eventual vet bills that might be prevented if dogs have this stuff all their lives, I prefer to keep them healthy now so we can avoid some of the absurdly expensive health issues later in life. I can't seem to leave a vet's office without a three-hundred-dollar bill, and that is for basically nothing. Anything serious can be one or two thousand or much higher. It strikes me as being smarter to try to prevent serious issues for as long as we can, and in the meantime, our three dogs are happy, healthy, and enjoying a good playtime with the ball every day. At mealtime, they don't hesitate to eat, and if we didn't get all the powder mixed in well with their food, they lick the bowls clean, getting every last bit of the supplement. After eating, they circle around to see if another dog left any traces of anything in the bowl, and if one misses some of this supplement powder, they lick it up. So it doesn't taste icky to my dogs. I researched the ingredients and am thinking about finding a human version of this stuff. I think the company has done a stellar job of researching what will actually help our dogs--and I know there are human supplements, made of approximately the same stuff, that reviewers rave about. I'm 76, but who knows? If I get the same nutrients, maybe I'll be more energetic as well and help chase that darned ball! First post: I got this, despite the price, just to see. My son has a seven-year-old Aussie who was no longer wanting to chase the ball, who stood back and just didn't seem to care about playing anymore with our two younger dogs. It was so sad to see! He is still so young. I remembered reading about Critical Immune Defense and seeing good reviews. So, despite the cost, I decided to order some. I gave my grand-dog, Gus, his three scoops (he's a larger dog than my girls, so they only get two) on his food per meal for three days. (I did mention to my son that I was doing so. It is his dog, after all.) So we sailed along for three days, and all of a sudden, my grand-dog, Gus, began bursting forward to chase the ball and play. He was like a puppy again, all excited and racing around. It made my heart swell, because I was thinking, "That Stuff is actually Working!" My son said nothing. So, I thought, okay, fine. I can do without spending all that money on snake poison, even though I believed I was seeing a huge change in my grand-dog, Gus. My thought was, "I saw a placebo effect. I convinced myself, so I believed in the hype." My son didn't mention seeing a difference. So, hello, the stuff is expensive. I decided not to buy anymore. I'm not an idiot. So a few days later, my son calls. (We live on the same property, so our dogs all eat together.) "Mom, are you still giving Gus his supplement?" I thought I had messed up, because I wasn't giving him anything. I was, like, WHAT supplement? My son was, like, that stuff that started making him play like a puppy again! He was very upset that I had stopped giving his dog the CID. He would have been eagerly willing to continue the supplement at his own cost and trouble! The difference in the dog was huge. I popped back, saying that he'd never said a word about how it changed Gus. Why would I continue giving it to him? The stuff is costly! (I hope the company can shave away at their overhead to reduce the cost of product. ) Bottom line, this stuff DOES work! It isn't about buying it and only thinking it works. It truly does, and our Gus is suddenly running and playing like a much younger dog. It has given him a new lease on life. I have decided to also give it to my two younger dogs, hopefully as a preventative supplement. And, hello, I'm researching to find a human-grade supplement with mostly the same ingredients. I could stand a boost energy to make me feel better, too!
Review: Great benefits but the price is extreme. - I am thoroughly impressed! My 17 year old dachshund acts like a pup again. She is living her best life. My 15 year old male Carin terrier who hasn’t been very active in a few years is now re engaging with the group. This stuff is amazing. Problem is I have 7 fur babies total. They are all 14 and up I know they would all benefit from using Critical immune Defense. But the price!. Why does it have to be so expensive???? 😢

## Features

- NEW LARGE JAR – SAME AMOUNT, MORE CONVENIENT! WE’VE REPLACED THE 3-PACK OF OUR SMALL 6.34 OZ JARS WITH ONE ECO-FRIENDLY, LARGE 19 OZ JAR CONTAINING THE EXACT SAME AMOUNT OF PRODUCT. SUBSCRIBERS: SWITCH NOW TO AVOID ANY GAPS IN YOUR PET’S IMMUNE SUPPORT ROUTINE. THE NEW JAR SAVES SPACE, REDUCES PACKAGING WASTE, IS EASIER TO STORE AND SCOOP, AND MAKES KEEPING YOUR DOG OR CAT HEALTHY EVEN SIMPLER.
- POWERFUL IMMUNE SYSTEM SUPPORT FOR DOGS & CATS - Veterinarian-developed formula that strengthens your pet’s immune system to help maintain health and support defense against common challenges. Ideal for dogs and cats of all breeds and ages, from active puppies and kittens to senior pets.
- PROMOTES NORMAL CELL GROWTH & LONG-TERM HEALTH - Unique blend of four medicinal mushrooms, concentrated white turmeric extract, and essential vitamins boosts natural killer (NK) and T-helper cells, helping healthy cells detect and address abnormalities for optimal wellness.
- REDUCES INFLAMMATION & SUPPORTS IMMUNE RESILIENCE - Formulated to promote a healthy inflammatory response and strengthen your pet’s natural defenses. Supports the body’s protective barrier against everyday environmental stressors that can challenge immune function. Rich in free-radical fighters to support cellular protection, enhance vitality, and promote a longer, healthier life for your pet.
- VET-FORMULATED, PREMIUM QUALITY – MADE IN THE USA Crafted by scientists and veterinarians using natural ingredients — free from artificial flavors, colors, or fillers — and produced under strict quality standards for results you can trust.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0FF48X78K |
| ASIN  | B0FF48X78K |
| Best Sellers Rank | #2,656 in Pet Supplies ( See Top 100 in Pet Supplies ) #11 in Dog Herbal Supplements |
| Brand Name | VetSmart Formulas |
| Color | Light brown |
| Customer Reviews | 4.3 4.3 out of 5 stars (1,683) |
| Date First Available | June 23, 2025 |
| Date First Available  | June 23, 2025 |
| Directions | For dogs and cats of all ages |
| Included Components | Critical Immune Defense |
| Item Package Dimensions L x W x H | 7.05 x 3.78 x 3.7 inches |
| Item Weight | 19 Ounces |
| Item model number | CID |
| Item model number  | CID |
| Manufacturer | Pet Wellness Direct |
| Manufacturer  | Pet Wellness Direct |
| Model Name | Critical Immune Defense |
| Package Dimensions  | 7.05 x 3.78 x 3.7 inches; 1.19 Pounds |
| Size | Pack of 1 - Large Size - (90-Day Supply) |
| Specific Uses for Product | Immune Defense |
| Target Audience Keyword | dogs |

## Product Details

- **Brand:** VetSmart Formulas
- **Flavor:** Hypo-allergenic Chicken Flavor
- **Item Form:** Powder
- **Item Volume:** 0.54 Kilograms
- **Item Weight:** 19 Ounces

## Images

![Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract (Large / 90 Day Avg. Supply) - Image 1](https://m.media-amazon.com/images/I/51Sp0a9ypQL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ I AM BACK TO BUY MORE!
*by C***R on August 9, 2024*

Update: We have only one bottle of powder left, so I'm reordering. I still have my grand-dog, Gus, on this supplement, and he is still running and chasing the ball during play time. My son is a firm believer in this product, and so am I. I have my younger female dogs on it as well. It is costly, but when I consider eventual vet bills that might be prevented if dogs have this stuff all their lives, I prefer to keep them healthy now so we can avoid some of the absurdly expensive health issues later in life. I can't seem to leave a vet's office without a three-hundred-dollar bill, and that is for basically nothing. Anything serious can be one or two thousand or much higher. It strikes me as being smarter to try to prevent serious issues for as long as we can, and in the meantime, our three dogs are happy, healthy, and enjoying a good playtime with the ball every day. At mealtime, they don't hesitate to eat, and if we didn't get all the powder mixed in well with their food, they lick the bowls clean, getting every last bit of the supplement. After eating, they circle around to see if another dog left any traces of anything in the bowl, and if one misses some of this supplement powder, they lick it up. So it doesn't taste icky to my dogs. I researched the ingredients and am thinking about finding a human version of this stuff. I think the company has done a stellar job of researching what will actually help our dogs--and I know there are human supplements, made of approximately the same stuff, that reviewers rave about. I'm 76, but who knows? If I get the same nutrients, maybe I'll be more energetic as well and help chase that darned ball! First post: I got this, despite the price, just to see. My son has a seven-year-old Aussie who was no longer wanting to chase the ball, who stood back and just didn't seem to care about playing anymore with our two younger dogs. It was so sad to see! He is still so young. I remembered reading about Critical Immune Defense and seeing good reviews. So, despite the cost, I decided to order some. I gave my grand-dog, Gus, his three scoops (he's a larger dog than my girls, so they only get two) on his food per meal for three days. (I did mention to my son that I was doing so. It is his dog, after all.) So we sailed along for three days, and all of a sudden, my grand-dog, Gus, began bursting forward to chase the ball and play. He was like a puppy again, all excited and racing around. It made my heart swell, because I was thinking, "That Stuff is actually Working!" My son said nothing. So, I thought, okay, fine. I can do without spending all that money on snake poison, even though I believed I was seeing a huge change in my grand-dog, Gus. My thought was, "I saw a placebo effect. I convinced myself, so I believed in the hype." My son didn't mention seeing a difference. So, hello, the stuff is expensive. I decided not to buy anymore. I'm not an idiot. So a few days later, my son calls. (We live on the same property, so our dogs all eat together.) "Mom, are you still giving Gus his supplement?" I thought I had messed up, because I wasn't giving him anything. I was, like, WHAT supplement? My son was, like, that stuff that started making him play like a puppy again! He was very upset that I had stopped giving his dog the CID. He would have been eagerly willing to continue the supplement at his own cost and trouble! The difference in the dog was huge. I popped back, saying that he'd never said a word about how it changed Gus. Why would I continue giving it to him? The stuff is costly! (I hope the company can shave away at their overhead to reduce the cost of product. ) Bottom line, this stuff DOES work! It isn't about buying it and only thinking it works. It truly does, and our Gus is suddenly running and playing like a much younger dog. It has given him a new lease on life. I have decided to also give it to my two younger dogs, hopefully as a preventative supplement. And, hello, I'm researching to find a human-grade supplement with mostly the same ingredients. I could stand a boost energy to make me feel better, too!

### ⭐⭐⭐⭐⭐ Great benefits but the price is extreme.
*by A***R on December 1, 2025*

I am thoroughly impressed! My 17 year old dachshund acts like a pup again. She is living her best life. My 15 year old male Carin terrier who hasn’t been very active in a few years is now re engaging with the group. This stuff is amazing. Problem is I have 7 fur babies total. They are all 14 and up I know they would all benefit from using Critical immune Defense. But the price!. Why does it have to be so expensive???? 😢

### ⭐⭐⭐⭐⭐ Great product! Dog started gaining weight when they were skinny.
*by M***N on January 5, 2026*

Great product! Improve my dog’s health right away. They did not like the taste, but covers up well with Fish type food.

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.us/products/762677543-critical-immune-defense-for-dogs-and-cats-supports-normal-cell](https://www.desertcart.us/products/762677543-critical-immune-defense-for-dogs-and-cats-supports-normal-cell)

---

*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-01-26*