---
product_id: 74567161
title: "Life Extension Same, 400 mg, Mood Health, 60 Enteric-Coated Tablets"
brand: "life extension"
price: "$77.56"
currency: USD
in_stock: true
category: "Life Extension"
url: https://www.desertcart.us/products/74567161-life-extension-same-400-mg-mood-health-60-enteric-coated
store_origin: US
region: United States of America
---

# Supports joint tissue health 400 mg clinically studied SAMe Boosts liver antioxidant glutathione Life Extension Same, 400 mg, Mood Health, 60 Enteric-Coated Tablets

**Brand:** life extension
**Price:** $77.56
**Availability:** ✅ In Stock

## Summary

> ✨ Elevate your mood, joints & liver health — because thriving is the new standard! 🧬

## Quick Answers

- **What is this?** Life Extension Same, 400 mg, Mood Health, 60 Enteric-Coated Tablets by life extension
- **How much does it cost?** $77.56 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/74567161-life-extension-same-400-mg-mood-health-60-enteric-coated)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Liver’s Best Ally:** Enhances glutathione production, your body’s natural defense against oxidative stress.
- • **Pure & Trusted Quality:** Non-GMO, gluten-free, vegetarian, and USA-made with expert-formulated precision.
- • **Mood Mastery in Every Dose:** Clinically studied 400 mg SAMe to help maintain a stable, positive mental outlook.
- • **Joint Comfort, All Day Long:** Promotes healthy joint tissue function so you can move with ease and confidence.
- • **Enteric-Coated for Maximum Absorption:** Special coating ensures SAMe reaches your intestines intact for superior effectiveness.

## Overview

Life Extension SAMe 400 mg delivers a potent, clinically studied dose of S-Adenosyl-Methionine in 60 enteric-coated vegetarian tablets. Designed to support stable mood, joint comfort, and liver health through enhanced glutathione production, this non-GMO, gluten-free supplement is crafted in the USA with premium ingredients and expert formulation for maximum bioavailability and trusted quality.

## Description

SAMe (S-Adenosyl-Methionine) is a popular nutrient formula for mood health, joint health and liver health. This mood support supplement contains 400 mg of clinically studied S-Adenosyl-Methionine in every dose. SAMe benefits many metabolic functions in the body, from mood and joint health to healthy glutathione production. SAMe contains 60 enteric-coated vegetarian tablets, enough for a 20- to 60-day supply. Non-GMO.

## Features

- A reason to smile – S-Adenosyl-Methionine (SAMe) is made naturally by your body. It has a variety of well-studied benefits, including that supplementing with SAMe helps maintain a stable mood and healthy mental outlook.
- Comfortable joints – SAMe helps promote joint tissue health and function. SAMe levels decline over time, so getting this daily, high-quality SAMe supplement will help keep you comfortable from head to toe!
- Liver protection – S-Adenosyl-Methionine (SAMe) helps your body produce glutathione, a powerful antioxidant that helps protect liver cells from oxidizing free radical compounds.
- Science matters – Expert formulators design our supplement formulas, and a Certificate of Analysis is available for every Life Extension product.
- Quality ingredients – The majority of our products are non-GMO, gluten-free and manufactured in the USA with internationally sourced ingredients.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07D2KF4TL |
| ASIN  | B07D2KF4TL |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #19,766 in Health & Household ( See Top 100 in Health & Household ) #519 in Blended Vitamin & Mineral Supplements |
| Brand Name | Life Extension |
| Color | Yellow Ochre |
| Container Type | Bottle |
| Customer Reviews | 4.7 4.7 out of 5 stars (817) |
| Date First Available  | May 12, 2018 |
| Diet Type | Vegetarian |
| Dosage Form | Tablet |
| Flavor | Unflavored |
| Global Trade Identification Number | 00737870217466 |
| Item Dimensions | 2.25 x 2.25 x 5 inches |
| Item Form | Tablet |
| Item Highlight | Mood, Joint & Liver Support, Gluten-Free, Non-GMO & Vegetarian |
| Item Weight | 3.52 ounces |
| Item model number  | 02174 |
| Manufacturer | Life Extension |
| Manufacturer  | Life Extension |
| Manufacturer Part Number | 02174 |
| Material Features | GMO Free |
| Material Type Free | Genetically Modified Organism (GMO) Free |
| Model Name | SAMe 400 mg |
| Model Number | 02174 |
| Number of Items | 1 |
| Primary Supplement Type | S-Adenosyl-Methionine |
| Product Benefits | Helps maintain stable mood, Promotes liver health, Supports healthy joint function |
| Product Dimensions  | 2.25 x 2.25 x 5 inches; 3.52 ounces |
| Special Ingredients | S-Adenosyl-Methionine |
| Specific Uses For Product | Joint Health, Liver Health & Detox, Mood Support |
| Total Servings Per Container | 60 |
| UPC | 737870217466 |
| Unit Count | 60 Count |

## Product Details

- **Brand:** Life Extension
- **Diet Type:** Vegetarian
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Item Weight:** 3.52 ounces
- **Item dimensions L x W x H:** 2.25 x 2.25 x 5 inches
- **Primary Supplement Type:** S-Adenosyl-Methionine
- **Product Benefits:** Helps maintain stable mood, Promotes liver health, Supports healthy joint function
- **Special Ingredients:** S-Adenosyl-Methionine
- **Unit Count:** 60 Count

## Images

![Life Extension Same, 400 mg, Mood Health, 60 Enteric-Coated Tablets - Image 1](https://m.media-amazon.com/images/I/71BRLIc8G5L.jpg)

## Questions & Answers

**Q: What are SAMe supplements good for?**
A: SAMe supplements benefit many critical metabolic functions in the body, help maintain a stable mood and support joint and liver health.

**Q: How does SAMe support healthy joints?**
A: SAMe supplements benefit many critical metabolic functions in the body, help maintain a stable mood and support joint and liver health.

**Q: What do SAMe supplements do for your mood?**
A: Research by the U.S. Department of Health and Human Services found that SAMe helps maintain a stable mood and healthy outlook.

**Q: Can you take SAMe every day?**
A: SAMe is safe to take every day according to the supplement label or the advice of your healthcare provider. These tablets are recommended one to three times daily to support a healthy mood.

**Q: Should I take SAMe at night or morning?**
A: It is suggested that these supplements are taken on an empty stomach or as recommended by a healthcare provider.

## Frequently Bought Together

- Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, Tablet, 60 Count
- Life Extension Neuro-Mag Magnesium L-Threonate, Magnesium L-threonate, Memory Health, Quick Thinking, Cognitive Health Support, Vegetarian, Non-GMO, 90 Vegetarian Capsules
- Life Extension TMG 500 mg – Trimethylglycine Supplement – Encourages Healthy Homocysteine Levels – Gluten-free – Non-gmo – Vegetarian – 60 Liquid Vegetarian Capsules

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-10-01*