---
product_id: 672273766
title: "Pharmaceris Refining Retinol 0.3% Night Cream – Encapsulated Retinol Smoothes Skin, Reduces Wrinkles & Blemishes and Unclogs Pores, Face Cream For Oily & Aging Skin, pureRETINOL 0.3, 1.35 fl oz"
brand: "pharmaceris"
price: "$63.00"
currency: USD
in_stock: false
reviews_count: 8
url: https://www.desertcart.us/products/672273766-pharmaceris-refining-retinol-0-3-night-cream-encapsulated-retinol-smoothes
store_origin: US
region: United States of America
---

# 4% biomimetic squalane hydration ceramide microspheres delivery 0.3% pure encapsulated retinol Pharmaceris Refining Retinol 0.3% Night Cream – Encapsulated Retinol Smoothes Skin, Reduces Wrinkles & Blemishes and Unclogs Pores, Face Cream For Oily & Aging Skin, pureRETINOL 0.3, 1.35 fl oz

**Brand:** pharmaceris
**Price:** $63.00
**Availability:** ❌ Out of Stock

## Summary

> 🌙 Unlock flawless nights: refine, hydrate, and glow with every sleep cycle!

## Quick Answers

- **What is this?** Pharmaceris Refining Retinol 0.3% Night Cream – Encapsulated Retinol Smoothes Skin, Reduces Wrinkles & Blemishes and Unclogs Pores, Face Cream For Oily & Aging Skin, pureRETINOL 0.3, 1.35 fl oz by pharmaceris
- **How much does it cost?** $63.00 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/672273766-pharmaceris-refining-retinol-0-3-night-cream-encapsulated-retinol-smoothes)

## Best For

- pharmaceris enthusiasts

## Why This Product

- Trusted pharmaceris brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Oil-Balancing Clarity:** Regulates sebum and unclogs pores to minimize blackheads and breakouts—perfect for oily/combination skin.
- • **Dual-Action Retinol Power:** Encapsulated 0.3% pure retinol targets wrinkles & blemishes for visibly smoother skin.
- • **Glow-Safe Routine Essential:** Use nightly with SPF protection to prevent sun sensitivity and reveal a radiant, youthful complexion.
- • **Deep Nourishment & Hydration:** Infused with shea butter, olive wax, cottonseed oil, and 4% biomimetic squalane for lasting moisture and skin barrier support.
- • **Scientifically Engineered Night Care:** Formulated to refine aging, blemish-prone skin with professional-grade efficacy you can trust at home.

## Overview

Pharmaceris Refining Retinol 0.3% Night Cream combines advanced encapsulated retinol technology with nourishing botanicals to smooth wrinkles, reduce blemishes, and balance oily or combination skin. Designed for adult skin showing early aging and imperfections, this scientifically formulated night cream delivers professional-level anti-aging and pore-refining benefits while deeply hydrating and supporting the skin’s lipid barrier. Ideal for those seeking clearer, firmer, and more radiant skin with a safe, gradual retinol introduction.

## Description

DUAL-ACTION NIGHT CARE – This advanced night cream is designed for adults with oily or combination skin prone to imperfections. Powered by 0.3% pure retinol in ceramide microspheres, it targets blemishes and visible signs of aging simultaneously, reducing imperfections while smoothing wrinkles for clearer, firmer skin. CLEARER, REFINED COMPLEXION – Retinol regulates sebum, unclogs and tightens pores, and restores balance, minimizing breakouts and blackheads. Regular use visibly improves skin texture and elasticity, leaving it smoother, more even, and refreshed every morning. NOURISHING HYDRATION & SAFETY – Enriched with shea butter, olive wax, cottonseed oil, and 4% biomimetic squalane, it nourishes, strengthens the lipid barrier, as well as prevents dryness or irritation. With proven safety and efficacy, this specialized formula delivers professional-level results at home. DIRECTIONS FOR USE – Apply nightly to cleansed face, avoiding the eye area. Start 2–3 times per week, then increase as tolerated. Always use sunscreen during the day, as retinol may increase skin’s sensitivity to sunlight. For best results, follow consistently. Ideal for anti aging skincare for women and men, especially for combination, oily and acne-prone skin.

Review: A great option for introducing retinol into your routine - This refining night cream is formulated with 0.3% pure retinol, making it a good option for those looking to improve skin texture, fine lines, and overall skin renewal. Retinol is known for its anti-aging and skin refining properties and reduce the appearance of wrinkles, uneven skin tone, and blemishes over time. Since this product contains 0.3% retinol, it’s best to start slowly, using it only a few times a week at first to allow the skin to adjust. It’s important to apply it at night on clean, dry skin, and always follow up with a moisturizer to keep the skin hydrated. Sunscreen is a must when using retinol, as it can increase sensitivity to the sun. Some people may experience mild redness or peeling when starting, which is normal as the skin adjusts. To minimize irritation, it’s recommended to pair it with a hydrating and soothing skincare routine. Overall, this dermo-night cream is a good option for those looking to incorporate retinol into their routine for smoother, more refined skin. Just remember to introduce it gradually and always wear SPF during the day!
Review: PureRetinol - I like how easy it is to squeeze the tube and to apply it. It absorbs quickly and dries completely without stickiness. Made my skin feel soft and matte with no pilling or irritation.

## Features

- RETINOL POWERED ANTI-AGING – With 0.3% pure retinol encapsulated in ceramide microspheres, it helps improve the appearance of fine lines and wrinkles, supporting smoother and firmer-looking skin, for a younger-looking complexion
- CLEARER, HEALTHIER SKIN – Retinol helps regulate sebum, unclogs pores, and minimizes imperfections like bumps, blackheads & redness, restoring balance in oily or combination, blemish-prone skin
- NOURISHING & HYDRATING COMFORT – Shea butter, olive wax, cottonseed oil, and 4% biomimetic squalane deeply hydrate, help support the lipid barrier and keep skin feeling soft, smooth, and moisturized
- SCIENTIFICALLY FORMULATED NIGHT CARE – Developed for adult skin with blemishes & early signs of aging, this night cream balances anti-wrinkle efficacy with refining care for blemish-prone skin to deliver visible results
- SUN SAFETY WARNING – Contains vitamin A (retinol), which may increase skin sensitivity to sunlight. Always use sunscreen, limit sun exposure, and protect skin while using and for a week afterward

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B0DK7HYFCD |
| Best Sellers Rank | #636,571 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #1,579 in Facial Night Creams |
| Customer Reviews | 4.3 4.3 out of 5 stars (32) |
| Manufacturer  | Dr Irena Eris |
| Product Dimensions  | 1.37 x 1.77 x 5.98 inches; 2.08 ounces |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** Pharmaceris
- **Item Volume:** 1.35 Fluid Ounces
- **Item dimensions L x W x H:** 1.37 x 1.77 x 5.98 inches
- **Special Feature:** Dermatologist tested, Reduces the appearance of blemishes, fine lines & wrinkles

## Images

![Pharmaceris Refining Retinol 0.3% Night Cream – Encapsulated Retinol Smoothes Skin, Reduces Wrinkles & Blemishes and Unclogs Pores, Face Cream For Oily & Aging Skin, pureRETINOL 0.3, 1.35 fl oz - Image 1](https://m.media-amazon.com/images/I/31+XbWMNh2L.jpg)
![Pharmaceris Refining Retinol 0.3% Night Cream – Encapsulated Retinol Smoothes Skin, Reduces Wrinkles & Blemishes and Unclogs Pores, Face Cream For Oily & Aging Skin, pureRETINOL 0.3, 1.35 fl oz - Image 2](https://m.media-amazon.com/images/I/51scfCB83uL.jpg)

## Questions & Answers

**Q: Who is this night cream best for?**
A: Adults with oily, combination, or blemish-prone skin who also want powerful anti-aging benefits. It’s ideal for reducing imperfections while smoothing wrinkles.

**Q: How long before I see results?**
A: Most users notice improved texture and reduced imperfections within a few weeks. Wrinkle-smoothing and brightening effects become more visible with consistent nightly use.

**Q: Can I use this with other skincare products?**
A: Yes, but avoid layering with other strong exfoliants or retinol products. Pair with gentle cleansers and hydrating creams. Always follow with sunscreen during the day.

**Q: Is it safe for sensitive skin?**
A: The formula is enriched with ceramides and squalane to minimize irritation, but start slow—2–3 times a week—and monitor your skin’s response.

## Customer Reviews

### ⭐⭐⭐⭐⭐ A great option for introducing retinol into your routine
*by A***E on February 17, 2025*

This refining night cream is formulated with 0.3% pure retinol, making it a good option for those looking to improve skin texture, fine lines, and overall skin renewal. Retinol is known for its anti-aging and skin refining properties and reduce the appearance of wrinkles, uneven skin tone, and blemishes over time. Since this product contains 0.3% retinol, it’s best to start slowly, using it only a few times a week at first to allow the skin to adjust. It’s important to apply it at night on clean, dry skin, and always follow up with a moisturizer to keep the skin hydrated. Sunscreen is a must when using retinol, as it can increase sensitivity to the sun. Some people may experience mild redness or peeling when starting, which is normal as the skin adjusts. To minimize irritation, it’s recommended to pair it with a hydrating and soothing skincare routine. Overall, this dermo-night cream is a good option for those looking to incorporate retinol into their routine for smoother, more refined skin. Just remember to introduce it gradually and always wear SPF during the day!

### ⭐⭐⭐⭐ PureRetinol
*by R***E on April 27, 2025*

I like how easy it is to squeeze the tube and to apply it. It absorbs quickly and dries completely without stickiness. Made my skin feel soft and matte with no pilling or irritation.

### ⭐⭐⭐⭐⭐ Gentle and lightweight!
*by S***! on March 21, 2025*

Non-irritating and feels good on my oily skin. I've just started using this product on my t-zone, but so far am very happy with how gentle it is. As a retinol product it's mild enough to use nightly, even for beginners. So far I'm impressed with this night cream.

## Frequently Bought Together

- Pharmaceris pureRETINOL 0.3 Refining Retinol Dermo-Night Cream with Encapsulated Retinol, Reduces the Appearance of Imperfections and Wrinkles, For Oily & Combination Skin, 1.35 fl oz
- Pharmaceris HYALURO SENSILIUM Hyaluronic Acid Water Dermo-Cream for Face, 1.35 fl oz, Allergic & Sensitive

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-02-13*