--- product_id: 6466968 title: "Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings)" brand: "integrative therapeutics" price: "$75.62" currency: USD in_stock: true reviews_count: 8 category: "Integrative Therapeutics" url: https://www.desertcart.us/products/6466968-integrative-therapeutics-similase-gfcf-digestive-enzyme-supplement-for-adults-supports store_origin: US region: United States of America --- # Dairy-free & vegan-friendly formula Reduces gas & bloating discomfort Supports gluten & casein digestion Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) **Brand:** integrative therapeutics **Price:** $75.62 **Availability:** ✅ In Stock ## Summary > 🌟 Unlock your gut’s potential—digest smarter, live freer! ## Quick Answers - **What is this?** Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) by integrative therapeutics - **How much does it cost?** $75.62 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/6466968-integrative-therapeutics-similase-gfcf-digestive-enzyme-supplement-for-adults-supports) ## Best For - integrative therapeutics enthusiasts ## Why This Product - Trusted integrative therapeutics brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Convenient 60-Serving Supply:** 120 capsules provide a full two-month regimen—perfect for busy professionals who demand consistent digestive balance. - • **Fast-Acting Relief from Bloating:** Clinically designed to ease occasional indigestion, gas, and bloating so you can stay energized and confident all day. - • **Trusted Quality with Proven Results:** Backed by 25+ years of Integrative Therapeutics’ commitment to potency, transparency, and clinical-grade manufacturing. - • **Clean, Plant-Based Digestive Support:** 100% dairy-free, vegan, and free from artificial colors or preservatives—because your gut deserves pure care. - • **Gluten & Casein Breakdown Powerhouse:** Harnesses DPP IV enzymes to neutralize tough gluten and casein peptides, letting you enjoy social meals without worry. ## Overview Integrative Therapeutics Similase GFCF is a premium digestive enzyme supplement formulated to support the breakdown of gluten and casein proteins, reducing digestive discomfort such as gas and bloating. This dairy-free, vegan-friendly formula contains no artificial additives and offers 60 servings per bottle, making it an ideal choice for adults seeking reliable digestive support with trusted quality from a brand with over 25 years of expertise. ## Description Formulated with Digestive Enzymes: Contains enzymes to support comprehensive digestion* Supports Gluten Digestion*: Supports dipeptidyl peptidase IV (DPP IV) activity for the digestion of proline-containing dipeptides from gluten and casein* Digestive Comfort Support*: Supports against occasional indigestion, gas and bloating* Enzyme Support Supplement*: Integrative Therapeutics Similase GFCF contains no dairy, or artificial colors, flavors, or preservatives. About Integrative Therapeutics: For over 25 years, patients and clinicians have trusted us for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you ## Features - Formulated with Digestive Enzymes: Contains enzymes to support comprehensive digestion* - Supports Gluten Digestion*: Supports dipeptidyl peptidase IV (DPP IV) activity for the digestion of proline-containing dipeptides from gluten and casein* - Digestive Comfort Support*: Supports against occasional indigestion, gas and bloating* - Enzyme Support Supplement*: Integrative Therapeutics Similase GFCF contains no dairy, or artificial colors, flavors, or preservatives. - About Integrative Therapeutics: For over 25 years, patients and clinicians have trusted us for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B004IN9SPS | | Age Range Description | Adult | | Best Sellers Rank | #30,063 in Health & Household ( See Top 100 in Health & Household ) #112 in Multi-Enzyme Nutritional Supplements | | Brand | Integrative Therapeutics | | Brand Name | Integrative Therapeutics | | Container Type | Bottle | | Customer Reviews | 4.6 out of 5 stars 894 Reviews | | Dosage Form | Capsule | | Flavor | Unflavored | | Item Dimensions | 2.43 x 2.43 x 4.26 inches | | Item Form | Capsule | | Item Weight | 3.2 ounces | | Manufacturer | Integrative Therapeutics | | Manufacturer Part Number | 73952 | | Material Features | No Artificial Colors | | Model Name | rative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Support Against Occasional Gas and Bloating* - Supports Gluten and Casein Digestion* - Dairy Free - 120 | | Model Number | 5570 | | Number of Items | 1 | | Primary Supplement Type | Microbial Enzymes | | Product Benefits | Digestive Health Support | | Total Servings Per Container | 60.0 | | UPC | 871791003866 885292713834 | | Unit Count | 120 Count | ## Product Details - **Age Range (Description):** Adult - **Brand:** Integrative Therapeutics - **Flavor:** Unflavored - **Item Form:** Capsule - **Item Weight:** 3.2 ounces - **Item dimensions L x W x H:** 2.43 x 2.43 x 4.26 inches - **Package Information:** Bottle - **Primary Supplement Type:** Microbial Enzymes - **Product Benefits:** Digestive Health Support - **Unit Count:** 120 Count ## Images ![Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) - Image 1](https://m.media-amazon.com/images/I/51SbrYQX2mL.jpg) ![Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) - Image 2](https://m.media-amazon.com/images/I/81CudWDtu7L.jpg) ![Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) - Image 3](https://m.media-amazon.com/images/I/51r+qFWMUxL.jpg) ![Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) - Image 4](https://m.media-amazon.com/images/I/81PU-lK9xxL.jpg) ![Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Adults - Supports Casein & Gluten Digestion* - Gas & Bloating Support* - Dairy-Free & Vegan - 120 Count (60 Servings) - Image 5](https://m.media-amazon.com/images/I/61OehCxRuuL.jpg) ## Available Options This product comes in different **Customer Package Type** options. ## Questions & Answers **Q: any legitimate research on this product?** A: No, there is not. There probably will be in the future though, and there is good reason to think that these kinds of products could be helpful for certain diseases though. This WSJ article is provides a good review on the subject: http://www.wsj.com/articles/SB10001424127887324557804578376562539148102. These things are unlikely to be harmful though, so it may be worth trying and seeing if it works for you. The only reason this supplement would work is if you don't produce enough enzymes on your own, which can happen in response to a bunch of different diseases. Also, 'legitimate research' would be any well controlled research rigorously executed with a large enough sample size, it would almost certainly come from an academic institution and be published in a peer reviewed journal. As Michelle points out, research by the makers of these supplements is unlikely to be 'legitimate', as they are incentivized not to control for placebo. **Q: what's the difference between this and the plain Similase?** A: The Similase physician-developed formula provides excellent digestive support of carbohydrate, protein, fat, fiber, and phytate under virtually all gastrointestinal pH conditions. Similase helps relieve occasional indigestion, gas, and bloating, and provides comprehensive support for digestion and assimilation of nutrients from the diet. Similase serves as the foundation for more targeted formulas in the Similase line including the Similase GFCF. The Similase GFCF takes into account the digestion of gluten and casein that can be particularly difficult for some individuals and is gluten free while the Similase is not gluten free. Similase GFCF provides enzymes to support comprehensive digestive health, while also featuring superior dipeptidyl peptidase IV (DPP IV) activity for the digestion of proline-containing dipeptides from gluten and casein. Similase GFCF supports a gluten-free, casein-free lifestyle and helps relieve occasional indigestion, gas, and bloating. **Q: Does this product contain milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten?** A: Integrative Therapeutics - Similase GFCF does not contain milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soy, tree nuts, wheat, or gluten. However it does contain yeast. **Q: Does this product contain milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten?** A: Similase® GFCF Supplement Facts:2 Veg Caps contain:Plant Enzymes (543mg) of:DPP IV Protease Blend (Protease I,II,III,IV,V) :Assay Method---FCC (pH 4.7) 134,600HUT---FCC (pH 7.0) 22,660PC---USP (pH 7.5) 12,556USPAmylase :Assay Method---FCC (pH 4.8) 9,530DU---USP (pH 6.8) 12,800USPLipase I,II :Assay Method---FCC (pH 6.5) 408LU---FIP (pH 7.0) 882FIPPhytase :Assay Method---Phytic Acid (pH 6.0) 0.67PULactase I,II :Assay Method---FCC (pH 4.5) 642ALUCellulase I, II :Assay Method---FCC (pH 4.5) 141CUSucrase (Invertase) :Assay Method---FCC (pH 4.6) 119INVUOther Ingredients: cellulose, vegetable capsule (modified cellulose), inulin (from chicory root), and silicon dioxide.Contains NO: sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, preservatives or ingredients of animal origin. It does not mention the exclusion of nuts but it does not show any in the ingredient list and Integrative Therapeutics is usually good about listing any known allergens...especially one like peanuts/nuts ## Customer Reviews ### ⭐⭐⭐⭐⭐ Review *by A***1 on May 6, 2019* ### ⭐⭐⭐⭐⭐ Review *by A***R on April 5, 2026* ### ⭐⭐⭐⭐⭐ Review *by J***. on August 23, 2025* ## Frequently Bought Together - Integrative Therapeutics Similase GFCF - Digestive Enzyme Supplement for Occasional Gas & Bloating* - Supports Gluten & Casein Digestion* - 120 Vegan Capsules - Integrative Therapeutics - Cortisol Manager - Supplement with Ashwagandha and L-Theanine - Supports Relaxation & Calm* - 30 Tablets - Integrative Therapeutics Active B-Complex - Energy Metabolism Support* - B-Complex Vitamin Supplement with 8 B-Vitamins, Vitamin B12, Folate, Choline - 60 Capsules --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/6466968-integrative-therapeutics-similase-gfcf-digestive-enzyme-supplement-for-adults-supports](https://www.desertcart.us/products/6466968-integrative-therapeutics-similase-gfcf-digestive-enzyme-supplement-for-adults-supports) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-05-18*