---
product_id: 646587325
title: "Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg"
brand: "vetoquinol"
price: "$112.09"
currency: USD
in_stock: true
reviews_count: 5
category: "Vetoquinol"
url: https://www.desertcart.us/products/646587325-vetoquinol-zylkene-calming-support-supplement-for-small-dogs-and-cats
store_origin: US
region: United States of America
---

# Lactose-free natural formula 75mg alpha-casozepine dose Easy sprinkle capsule delivery Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg

**Brand:** vetoquinol
**Price:** $112.09
**Availability:** ✅ In Stock

## Summary

> 🐕‍🦺 Keep Calm & Carry On: Stress-Free Pets, Happy Homes!

## Quick Answers

- **What is this?** Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg by vetoquinol
- **How much does it cost?** $112.09 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/646587325-vetoquinol-zylkene-calming-support-supplement-for-small-dogs-and-cats)

## Best For

- vetoquinol enthusiasts

## Why This Product

- Trusted vetoquinol brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Vet-Backed Calm:** Clinically formulated with 75mg alpha-casozepine for effective daily anxiety relief without drowsiness.
- • **Gut-Friendly Formula:** Lactose-free and gentle on sensitive stomachs, ensuring your pet stays calm and comfortable.
- • **Stress-Proof Routine:** Simple capsule powder to mix into food—stress relief that fits seamlessly into busy lifestyles.
- • **Trusted by Pet Parents:** Thousands of 5-star reviews prove Zylkene’s power to reduce stress and improve behavior in small dogs and cats.
- • **Versatile Anxiety Support:** Ideal for travel, vet visits, loud noises, and separation—help your pet thrive through life’s disruptions.

## Overview

Vetoquinol Zylkene is a veterinarian-recommended calming supplement for small dogs and cats, delivering 75mg of natural alpha-casozepine daily. This lactose-free, non-drowsy formula supports pets through anxiety triggers like travel, vet visits, and loud noises by promoting relaxation and reducing stress-related behaviors. Easy to administer by sprinkling capsule contents over food, Zylkene fits effortlessly into daily routines, helping pets stay calm and balanced without side effects.

## Description

Support your pet's everyday health with Vetoquinol Zylkene. This gentle calming support supplement is designed to support small dogs and cats as they relax and adapt during challenging situations without causing drowsiness. This formula provides support for occasional anxiety related to everyday life changes, such as being home alone, vet visits, travelling, celebrations, and loud noises. Made with carefully selected natural ingredients, including alpha-casozepine, a naturally occurring milk protein, this pet wellness supplement supports sensitive stomachs with a lactose-free and preservative-free formula. This non-drowsy supplement offers balanced behavior support, making it ideal for pets needing support with behaviors such as chewing, drooling, hiding, house-soiling, and excessive licking. It seamlessly mixes into food for a stress-free daily routine. For best use, begin giving this oral capsule 1–2 days before an anticipated stressful event. Some pets may benefit from starting 5–7 days ahead for optimal effectiveness. For easy, daily use, open the capsule and sprinkle the powder over pet food. Zylkene is part of Vetoquinol, a family-owned animal health company dedicated to improving the well-being of pets and the people who love them. Our products are shaped by veterinary insight, thoughtful formulation, and a belief that pet care should be simple and dependable for every household. We are committed to creating solutions that help support daily routines and foster the joyful moments pets bring into our lives.

Review: Anxiety Ridden Cat Approved for marking! - My kitty Goose is the only one of 4 indoor cats we have that has had a terrible problem of marking (he’s 10 this year and this began 2 years ago) in one room of the house. Same spot over and over, no amount of enzyme cleaner or cleaning of the area and direct spot cleaning has made him stop. I was at my wits end and didn’t know what other steps to take, before going to the vet (he has been cleared of any medical complications) for prescribed medication, I figured I’d give this a shot. I give him one pill in the morning mixed with a quarter of his squeezable treat and he has completely stopped, he is much calmer overall, and actually seems at peace now. There are no side affects aside from the first dose where he literally looked like he was stoned for about an hour lmfao that has since stopped, and he acts completely normal after his dose (for his weight is recommended two, I only give him one) and he doesn’t notice any taste or smell from it, he gets excited when I shake the bottle in the mornings to mix it for him! I highly recommend this product for people struggling with a cat who has high anxiety or marking issues! From a very relieved cat mom who was ready to throw in the towel.
Review: Great product - Great product just a little expensive

## Features

- Help Your Pet Cope With External Stress - Zylkene helps your pet cope with changes in their daily routine, such as travel, celebrations, vet visits, home alone, boarding, loud noises, and more
- Alpha-Casozephine - A naturally occurring milk protein found in cow's milk that helps promote calming effects in your pet without drowsiness or other side effects found in other calming chews for dogs
- Lactose-Free and Easy on Sensitive Stomachs - Zylkene's dog calming and cat calming supplements are lactose-free and made with natural ingredients that are easy on sensitive stomachs
- Veterinarian Recommended Daily Calming Support - Zylkene promotes calming in dogs and cats and can be given daily for behavior support and to help deal with unexpected external stresses
- Easy to Administer - Open the capsule of Zylkene and add it to your pet's food daily to help them cope with external stresses like separation and improve daily behavior

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07S5KTWLQ |
| Active Ingredients | Active Ingredients: Hydrolyzed Milk Protein (Bovine): 75 mg (providing alpha-casozepine) |
| Best Sellers Rank | #11,340 in Pet Supplies ( See Top 100 in Pet Supplies ) #22 in Dog Relaxants |
| Brand | Vetoquinol |
| Brand Name | Vetoquinol |
| Customer Reviews | 4.1 out of 5 stars 3,478 Reviews |
| Dog Breed Size | Small |
| Flavor | Milk |
| Flavour | Milk |
| Item Form | Capsule |
| Item form | Capsule |
| Manufacturer | Vetoquinol |
| Manufacturer Part Number | 424083 |
| Model Number | 424083 |
| Number of Items | 1 |
| Product Benefits | Anxiety Relief,Promote Relaxation,Reduce Stress |
| Product benefits | Anxiety Relief,Promote Relaxation,Reduce Stress |
| Specific Uses For Product | anxiety, moving, stress, thunderstorms |
| Target Species | Dog |
| Unit Count | 30 Count |

## Product Details

- **Active Ingredients:** Active Ingredients: Hydrolyzed Milk Protein (Bovine): 75 mg (providing alpha-casozepine)
- **Brand:** Vetoquinol
- **Flavour:** Milk
- **Item form:** Capsule
- **Product benefits:** Anxiety Relief,Promote Relaxation,Reduce Stress

## Images

![Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg - Image 1](https://m.media-amazon.com/images/I/51QLGn+90YL.jpg)

## Available Options

This product comes in different **Size** options.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Anxiety Ridden Cat Approved for marking!
*by A***R on 14 May 2026*

My kitty Goose is the only one of 4 indoor cats we have that has had a terrible problem of marking (he’s 10 this year and this began 2 years ago) in one room of the house. Same spot over and over, no amount of enzyme cleaner or cleaning of the area and direct spot cleaning has made him stop. I was at my wits end and didn’t know what other steps to take, before going to the vet (he has been cleared of any medical complications) for prescribed medication, I figured I’d give this a shot. I give him one pill in the morning mixed with a quarter of his squeezable treat and he has completely stopped, he is much calmer overall, and actually seems at peace now. There are no side affects aside from the first dose where he literally looked like he was stoned for about an hour lmfao that has since stopped, and he acts completely normal after his dose (for his weight is recommended two, I only give him one) and he doesn’t notice any taste or smell from it, he gets excited when I shake the bottle in the mornings to mix it for him! I highly recommend this product for people struggling with a cat who has high anxiety or marking issues! From a very relieved cat mom who was ready to throw in the towel.

### ⭐⭐⭐⭐⭐ Great product
*by L***A on 7 June 2026*

Great product just a little expensive

### ⭐⭐⭐⭐ Effective for calming.
*by A***A on 14 April 2026*

I find this good for calming. It’s hard to say if this alone is helping but I do see a difference. It helps if it’s taken daily rather than as needed. It’s expensive so taking off one star.

## Frequently Bought Together

- Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg
- Purina Pro Plan Veterinary Supplements Calming Care Cat Supplements - 30 ct. Box
- FELIWAY® Classic Cat Calming Spray, 60ml - Comforts Cats at Home and On the Go and Helps to Calm During Travel

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.us/products/646587325-vetoquinol-zylkene-calming-support-supplement-for-small-dogs-and-cats](https://www.desertcart.us/products/646587325-vetoquinol-zylkene-calming-support-supplement-for-small-dogs-and-cats)

---

*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-07-11*