--- product_id: 607508103 title: "Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 4 oz" brand: "advil" price: "$42.16" currency: USD in_stock: true reviews_count: 8 category: "Advil" url: https://www.desertcart.us/products/607508103-advil-targeted-relief-pain-relieving-cream-up-to-8-hours store_origin: US region: United States of America --- # Up to 8 hours relief 4 powerful analgesics combined Dual warming & cooling action Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 4 oz **Brand:** advil **Price:** $42.16 **Availability:** ✅ In Stock ## Summary > 🔥❄️ Target pain like a pro — relief that works as hard as you do! ## Quick Answers - **What is this?** Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 4 oz by advil - **How much does it cost?** $42.16 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/607508103-advil-targeted-relief-pain-relieving-cream-up-to-8-hours) ## Best For - advil enthusiasts ## Why This Product - Trusted advil brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Long-Lasting Power:** Experience up to 8 hours of targeted pain relief that keeps you moving through your busiest days. - • **Dual Sensation Therapy:** Feel the unique warming and cooling effects that enhance comfort and accelerate recovery. - • **Prescription-Free Relief:** Get powerful, doctor-trusted pain relief without the hassle of prescriptions—ideal for managing arthritis, muscle, joint, and back pain. - • **Non-Greasy, Quick Absorption:** Glides on smoothly without leaving residue, perfect for on-the-go professionals who demand comfort and discretion. - • **Quadruple Pain-Fighting Formula:** Harness the strength of four active ingredients—Camphor, Capsaicin, Menthol, and Methyl Salicylate—for fast, deep relief. ## Overview Advil Targeted Relief Pain Relieving Cream delivers fast, deep-penetrating relief for minor arthritis, muscle, joint, and back pain with a unique blend of four active analgesics. Its dual warming and cooling sensations provide a soothing experience that lasts up to 8 hours, all in a non-greasy, easy-to-apply formula. Prescription-free and HSA/FSA eligible, it’s the smart choice for busy professionals seeking effective, on-demand pain management. ## Description Advil Targeted Relief Pain Relieving Cream – Your Fast-Acting Solution for Tough Pain! Designed to quickly tackle pain four ways: targets, penetrates, blocks, and relieves. This innovative formula delivers deep penetrating relief right where it hurts. Experience quick application and relief. Our powerful pain-fighting formula starts working on contact, delivering fast relief with a cooling plus a warming sensation that you can feel during application. Also, Targeted Relief doesn't leave your skin feeling dry or greasy, ensuring comfort with every use. This cream is your go-to for deep, penetrating relief that directly targets pain at the source. Its unique formula penetrates to the nerves, working on signaling pathways receptors to provide pain relief. No prescription required. Get back to doing what you love, without the burden of pain. Get ready to head back to college with confidence and stock up ensuring you're ready for anything the academic year throws your way. Choose Advil Targeted Relief Pain Relieving Cream – your ultimate companion for fast, effective pain relief right where you need it most. (1) Among the leading pain relief brands Review: I smell like a granny and feel like a million! - I highly recommend this for sciatic nerve pain due to piriformis syndrome. It helps at 100% where other helpful products only reach 50% at best. It's such a relief that I don't mind the smell at all. There are a lot of products available to help alleviate sciatic pain and sciatic pain from piriformis syndrome in particular. There are exercises that help and lifestyle changes that can address the underlying problem as well. I've tried just about everything available that you can purchase. I do the exercises. I'm making the lifestyle changes. Most of the products and exercises that are supposed to help do help to one extent or another , but even combining a variety of them has never been sufficient to handle a really intense stretch of pain coming from the piriformis syndrome. It hurts not only as a muscle site but all down my left leg. In the calf when it gets down to that area it's mostly on the outside and a bit towards the front and back. That area of pain feels a bit like a non-stop charlie horse at times, and at other times it feels like it's on fire almost. This morning the pain was so bad even having a copper leg brace on and the kind of brace that they sell that puts pressure on the points in the calf and having taken the ibuprofen and tylenol. I couldn't get the pain reduced to a point where I could have comfort at all and I was really miserable. I used one of my massage guns and that would just address the pain in one area and then the other areas would still hurt. I opened the Advil pain cream as soon as it was delivered. The cream has a light texture and it absorbs very quickly . My skin is on the dry side which might affect this but after I apply the cream my skin doesn't feel greasy or sticky. The smell is very strong and I think it's stronger than other kinds of rubs perhaps or maybe it just seems that way at the moment. It's not bad, it just has that muscle rub smell. Within minutes of applying the cream I noticed and Improvement. At first I thought maybe it was in my head but sure enough within 15 minutes the pain was reduced to where I could get up and walk to my kitchen and back within a tolerable level of pain. Within a half hour, now I'm just feeling a little pain at the very top of my left thigh in the back and it's not severe at all. I think I'm only noticing it because I'm actively considering how my leg feels for the purpose of this review. I also still feel some tightness, similar to when I do a deep stretch, in the area of my lower leg that not that long ago felt almost like it was having an endless charlie horse. It doesn't hurt. It's just some tightness in that area. And that's it! I didn't even use a super heavy application of the cream, and within half an hour anything going on with my leg wouldn't even be worth mentioning. Of course I still have to make lifestyle Changes in order for the pain to be fully resolved the majority of the days of the year but for flare-ups and plan to continue using this Advil pain cream. It's worth the trade off in having that muscle rub smell about my person. If it's having the pain completely shut me down so there's nothing I can really do VS. smelling like muscle rub, I'll take smelling like muscle rub. Another great thing I should probably add is that I have fairly sensitive skin and the Advil pain cream did not cause any irritation or rash. I highly recommend this pain cream from Advil Review: Works as described - Advil Target pain relief is on contact for 8 hrs or more. Good for daily use. The consistency is not thick and non greasy. No harsh scent, pricing is fair for the size. I use daily before I start working. A good ease of pain for my thumb pain throughout the day. ## Features - One 4 oz Tube of Advil Targeted Relief Pain Relieving Cream - The only topical pain reliever with 4 powerful pain-fighting ingredients (1) - Provides a warming & cooling sensation on contact and lasts up to 8 hours (1) - Designed to quickly tackle pain four ways: targets, penetrates, blocks, and relieves - Fast and powerful relief for minor arthritis pain, muscle, joint and back pain - the perfect addition to your college dorm room essentials - Doesn't leave your skin feeling dry or greasy and easily glides onto skin, ensuring comfort with every use - Provides both cooling and warming sensations to enhance the pain relief experience - Topical pain relief without needing a prescription - HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0CTTLFN9G | | ASIN | B0CTTLFN9G | | Active Ingredients | Camphor 3.1% - Topical analgesic Capsaicin 0.025% - Topical analgesic Menthol 10% - Topical analgesic Methyl salicylate 15% - Topical analgesic | | Additional Features | Fast-Acting, Targeted | | Age Range Description | Adult | | Best Sellers Rank | #3,323 in Health & Household ( See Top 100 in Health & Household ) #13 in Joint & Muscle Pain Relief Rubs | | Brand Name | Advil | | Customer Reviews | 4.4 4.4 out of 5 stars (4,830) | | Date First Available | February 2, 2024 | | Dosage Form | Cream | | Global Trade Identification Number | 00305736555511 | | Item Dimensions | 1.7 x 2.6 x 8 inches | | Item Form | Cream | | Item Weight | 4.94 Ounces | | Item model number | 60000000203477 | | Manufacturer | Haleon US Services Inc. | | Manufacturer | Haleon US Services Inc. | | Manufacturer Part Number | 60000000203477 | | Model Number | 60000000203477 | | Number of Items | 1 | | Package Type Name | Tube | | Product Benefits | Pain Relief | | Product Dimensions | 1.7 x 2.6 x 8 inches; 4.94 ounces | | Specific Uses For Product | Muscle Pain | | Target Use Body Part | Head | | UPC | 305736555511 | | Unit Count | 4.0 Ounce | ## Product Details - **Brand:** Advil - **Item Weight:** 4.94 Ounces - **Item dimensions L x W x H:** 1.7 x 2.6 x 8 inches - **Product Benefits:** Pain Relief - **Specific Uses For Product:** Muscle Pain ## Images ![Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 4 oz - Image 1](https://m.media-amazon.com/images/I/812njFxqz1L.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: What is Advil Targeted Relief Pain Relieving Cream?** A: This product is a topical pain-relieving cream with a unique formula that penetrates to the nerves where it works on pain receptors to relieve tough pain. **Q: What pain does Advil Targeted Relief treat?** A: Advil Targeted Relief treats minor arthritis pain, joint pain, lower back pain, muscle pain and more. **Q: How long does Advil Targeted Relief Pain Relieving Cream work for?** A: This product provides pain relief for up to 8 hours. **Q: How often can I use this product?** A: For adults and children 12 years and older; apply to affected area not more than 3 to 4 times daily. Children under 12 years of age should consult a doctor. **Q: How do you use Advil Targeted Relief Pain Relieving Cream?** A: Clean and dry the affected area. Remove cap and gently squeeze to dispense cream. Massage cream onto skin. ## Customer Reviews ### ⭐⭐⭐⭐⭐ I smell like a granny and feel like a million! *by J***1 on March 3, 2026* I highly recommend this for sciatic nerve pain due to piriformis syndrome. It helps at 100% where other helpful products only reach 50% at best. It's such a relief that I don't mind the smell at all. There are a lot of products available to help alleviate sciatic pain and sciatic pain from piriformis syndrome in particular. There are exercises that help and lifestyle changes that can address the underlying problem as well. I've tried just about everything available that you can purchase. I do the exercises. I'm making the lifestyle changes. Most of the products and exercises that are supposed to help do help to one extent or another , but even combining a variety of them has never been sufficient to handle a really intense stretch of pain coming from the piriformis syndrome. It hurts not only as a muscle site but all down my left leg. In the calf when it gets down to that area it's mostly on the outside and a bit towards the front and back. That area of pain feels a bit like a non-stop charlie horse at times, and at other times it feels like it's on fire almost. This morning the pain was so bad even having a copper leg brace on and the kind of brace that they sell that puts pressure on the points in the calf and having taken the ibuprofen and tylenol. I couldn't get the pain reduced to a point where I could have comfort at all and I was really miserable. I used one of my massage guns and that would just address the pain in one area and then the other areas would still hurt. I opened the Advil pain cream as soon as it was delivered. The cream has a light texture and it absorbs very quickly . My skin is on the dry side which might affect this but after I apply the cream my skin doesn't feel greasy or sticky. The smell is very strong and I think it's stronger than other kinds of rubs perhaps or maybe it just seems that way at the moment. It's not bad, it just has that muscle rub smell. Within minutes of applying the cream I noticed and Improvement. At first I thought maybe it was in my head but sure enough within 15 minutes the pain was reduced to where I could get up and walk to my kitchen and back within a tolerable level of pain. Within a half hour, now I'm just feeling a little pain at the very top of my left thigh in the back and it's not severe at all. I think I'm only noticing it because I'm actively considering how my leg feels for the purpose of this review. I also still feel some tightness, similar to when I do a deep stretch, in the area of my lower leg that not that long ago felt almost like it was having an endless charlie horse. It doesn't hurt. It's just some tightness in that area. And that's it! I didn't even use a super heavy application of the cream, and within half an hour anything going on with my leg wouldn't even be worth mentioning. Of course I still have to make lifestyle Changes in order for the pain to be fully resolved the majority of the days of the year but for flare-ups and plan to continue using this Advil pain cream. It's worth the trade off in having that muscle rub smell about my person. If it's having the pain completely shut me down so there's nothing I can really do VS. smelling like muscle rub, I'll take smelling like muscle rub. Another great thing I should probably add is that I have fairly sensitive skin and the Advil pain cream did not cause any irritation or rash. I highly recommend this pain cream from Advil ### ⭐⭐⭐⭐⭐ Works as described *by S***. on April 11, 2026* Advil Target pain relief is on contact for 8 hrs or more. Good for daily use. The consistency is not thick and non greasy. No harsh scent, pricing is fair for the size. I use daily before I start working. A good ease of pain for my thumb pain throughout the day. ### ⭐⭐⭐⭐⭐ It works *by C***W on April 3, 2026* The good thing about it is that it does actually work. However, the smell is overwhelming. Don't put it on if you have to go out immediately. The pain does come back but for temporary relief it is very good. ## Frequently Bought Together - Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 4 oz - Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules - Advil Targeted Relief Pain Relieving Cream with Massage Applicator, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain, 2.5 oz --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/607508103-advil-targeted-relief-pain-relieving-cream-up-to-8-hours](https://www.desertcart.us/products/607508103-advil-targeted-relief-pain-relieving-cream-up-to-8-hours) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-05-11*