---
product_id: 603060365
title: "II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply"
brand: "k9 advantix"
price: "$59.52"
currency: USD
in_stock: true
category: "K9 Advantix"
url: https://www.desertcart.us/products/603060365-ii-large-dog-vet-recommended-flea-tick-and-mosquito-treatment
store_origin: US
region: United States of America
---

# For dogs 21-55 lbs Waterproof after 24 hours Kills fleas in 12 hours II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply

**Brand:** k9 advantix
**Price:** $59.52
**Availability:** ✅ In Stock

## Summary

> 🐾 Stay ahead of pests — because your dog deserves the best defense!

## Quick Answers

- **What is this?** II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply by k9 advantix
- **How much does it cost?** $59.52 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/603060365-ii-large-dog-vet-recommended-flea-tick-and-mosquito-treatment)

## Best For

- k9 advantix enthusiasts

## Why This Product

- Trusted k9 advantix brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Waterproof Protection:** Keeps working even after your dog’s outdoor adventures post 24 hours
- • **Effortless Application:** Fragrance-free, topical spot-on treatment that’s quick and mess-free
- • **No Prescription Needed:** Convenient OTC access so your dog stays protected without delays
- • **Rapid Flea Elimination:** Kills fleas within 12 hours to stop infestations fast
- • **All-in-One Pest Defense:** Vet-recommended formula repels & kills fleas, ticks, mosquitoes, biting flies, and lice

## Overview

K9 Advantix II Large Dog is a vet-recommended, topical flea, tick, mosquito, biting fly, and lice treatment designed for dogs weighing 21-55 lbs. It kills fleas within 12 hours and provides waterproof protection after 24 hours. This fragrance-free, easy-to-apply formula requires no prescription and offers monthly, comprehensive pest prevention to keep your dog comfortable and healthy.

## Description

K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21-55 lbs. to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.

## Features

- K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07NX5BJK8 |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | Adult |
| Best Sellers Rank | #58,641 in Pet Supplies ( See Top 100 in Pet Supplies ) #77 in Dog Flea Drops |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.3 4.3 out of 5 stars (5,362) |
| Global Trade Identification Number | 00724089114938 |
| Item Form | Topical |
| Item Weight | 0.01 Ounces |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 90204385 |
| Model Number | 90204385 |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089114938 |
| Unit Count | 1 Count |
| Volume | 2.5 Milliliters |

## Product Details

- **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen
- **Brand:** K9 Advantix
- **Item form:** Topical
- **Item weight:** 0.01 Ounces
- **Scent:** Unscented

## Images

![II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - Image 1](https://m.media-amazon.com/images/I/71Ku9s2eqnL.jpg)

## Frequently Bought Together

- K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply
- K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 1-Mo Supply
- K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 1-Mo Supply

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-05-21*