---
product_id: 5791400
title: "StressGuard Slime Coat Protection - Stress and Toxic Ammonia Reducer 250 ml"
brand: "seachem"
price: "$30.89"
currency: USD
in_stock: true
reviews_count: 13
category: "Seachem"
url: https://www.desertcart.us/products/5791400-stressguard-slime-coat-protection-stress-and-toxic-ammonia-reducer-250
store_origin: US
region: United States of America
---

# reduces ammonia toxicity & stress targets wounds & promotes healing pH neutral (7.0) for reef-safe use StressGuard Slime Coat Protection - Stress and Toxic Ammonia Reducer 250 ml

**Brand:** seachem
**Price:** $30.89
**Availability:** ✅ In Stock

## Summary

> 🐠 Heal, Protect, Thrive — Because Your Fish Deserve the Best!

## Quick Answers

- **What is this?** StressGuard Slime Coat Protection - Stress and Toxic Ammonia Reducer 250 ml by seachem
- **How much does it cost?** $30.89 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/5791400-stressguard-slime-coat-protection-stress-and-toxic-ammonia-reducer-250)

## Best For

- seachem enthusiasts

## Why This Product

- Trusted seachem brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Targeted Healing Action:** Colloidal agents bind directly to wounds, accelerating recovery and preventing infections.
- • **Versatile & Easy Dosage:** Use 2.5–5 mL per 40L daily, with safe double dosing for rapid relief.
- • **Stress & Toxicity Reducer:** Effectively lowers toxic ammonia levels and calms fish during transport or handling.
- • **Reef-Safe pH Neutral Formula:** Maintains stable aquarium conditions without harming sensitive invertebrates or plants.
- • **Trusted by Aquarists Worldwide:** Highly rated with 4.8 stars and proven success on stubborn fin rot and dropsy cases.

## Overview

Seachem StressGuard is a premium liquid treatment designed to reduce fish stress and toxic ammonia exposure while promoting rapid healing of wounds and infections. Its pH-neutral formula ensures safe use in reef and planted aquariums, making it a must-have for professional and hobbyist aquarists seeking to maintain vibrant, healthy aquatic life.

## Description

Seachem StressGuard Slime Coat Protection - Stress and Toxic Ammonia Reducer 250 ml

Review: Must have!!! - This stuff is always great to have on hand, blue in color, no smell and doesn’t do much for water clarity as it is solely for aiding fish healing and health, definitely acts as a medication and works great for even fish with dropsy. We had rescued a dropsy fish from PetSmart and he had severe spinal curvature, we put him in a hospital tank to live the rest of his life happy, and he lasted almost an entire year!!!
Review: Saved my betta - My betta had awful fin rot that wasn’t getting better with anything else I tried. A few weeks after using this and his fins are showing growth and he’s back to his usual activity level. Would absolutely recommend for anyone whose fish has stubborn fin rot.

## Features

- PROTECT: Seachem StressGuard is a premium slime coat protection product, working to reduce stress and ammonia toxicity whenever handling or transporting ﬁsh.
- HEAL: Seachem StressGuard binds to exposed protein in wounds to promote healing of injured ﬁsh while reducing the likelihood of primary and secondary infections.
- TREATMENT: The protein active colloidal agent in StressGuard actively seeks out any wounds, abrasions, or places where exposed proteins are and attaches to this area, helping to directly deliver the disinfectant in the product and start the healing process.
- AQUARIUM CARE: Use 1/2–1 capful (2.5–5 mL) of StressGuard to every 40 L (10 US gallons) every 24 hours until signs of stress have abated or healing is complete. A dose of StressGuard may be safely doubled.
- SAFETY: StressGuard has a pH of 7.0. It will not affect the pH of an aquarium, even at large doses, allowing for safe use in a reef or planted aquarium containing invertebrates

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0002APILY |
| ASIN  | B0002APILY |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #16,872 in Pet Supplies ( See Top 100 in Pet Supplies ) #150 in Aquarium Water Treatments |
| Brand Name | Seachem |
| Customer Reviews | 4.8 4.8 out of 5 stars (1,596) |
| Date First Available  | June 15, 2004 |
| Department  | Unisex-Adult |
| Global Trade Identification Number | 00716184594395 |
| Included Components | Seachem Stress Guard 250 Milliliter |
| Is Discontinued By Manufacturer  | No |
| Item Form | Liquid |
| Item Type Name | Seachem Stress Guard 250 Milliliter |
| Item Weight | 241 Grams |
| Item model number  | 526 |
| Liquid Volume | 250 Milliliters |
| Manufacturer | Seachem Laboratories, Inc. |
| Manufacturer  | Seachem Laboratories, Inc. |
| Manufacturer Part Number | 075264 |
| Model Number | 526 |
| Product Dimensions  | 1.94 x 1.94 x 6.5 inches; 8.5 ounces |
| Target Species | Fish |
| UPC | 716184594395 000116052603 |
| Unit Count | 250 Milliliters |
| Warranty Description | Warranty |

## Product Details

- **Brand:** Seachem
- **Item Form:** Liquid
- **Item Weight:** 241 Grams
- **Liquid Volume:** 250 Milliliters
- **Manufacturer:** Seachem Laboratories, Inc.

## Images

![StressGuard Slime Coat Protection - Stress and Toxic Ammonia Reducer 250 ml - Image 1](https://m.media-amazon.com/images/I/61u0G1o50JL.jpg)

## Available Options

This product comes in different **Size, Style** options.

## Questions & Answers

**Q: Is this also used as a conditioner as well? Or do i have to use my prime water conditioner with this?**
A: No,I would say it is not. You would have to use Prime to condition your water. You can always e-mail Seachem and ask. I use lots of their products. One of the best companies out there. They have answered everyone of my e-mails.

**Q: Is this OK to use with freshwater snails?**
A: I chuckled when I saw your question;  I use this product every time I do a water change, and since last winter I have been battling snails that came in unbeknownst to me on some plants (75 gal freshwater tank, lightly planted with low light tolerant plants).  And they are prolific!!  Based on my experience, I would say it it doesn't harm snails HOWEVER, not being an aqua-malacologist, I don't know if different species of snails react differently to meds.  You could always send a question to Seachem to confirm.  I do work with plants a lot, so a tip; if you know what kind of snails you have, include that information with your inquiry.

**Q: Can this product be used for saltwater aquariums?**
A: yes

**Q: Can this be used with Seachem prime?**
A: Yes

## Customer Reviews

### ⭐⭐⭐⭐⭐ Must have!!!
*by A***A on January 17, 2026*

This stuff is always great to have on hand, blue in color, no smell and doesn’t do much for water clarity as it is solely for aiding fish healing and health, definitely acts as a medication and works great for even fish with dropsy. We had rescued a dropsy fish from PetSmart and he had severe spinal curvature, we put him in a hospital tank to live the rest of his life happy, and he lasted almost an entire year!!!

### ⭐⭐⭐⭐⭐ Saved my betta
*by F***R on January 25, 2026*

My betta had awful fin rot that wasn’t getting better with anything else I tried. A few weeks after using this and his fins are showing growth and he’s back to his usual activity level. Would absolutely recommend for anyone whose fish has stubborn fin rot.

### ⭐⭐⭐⭐⭐ Good product
*by K***E on March 1, 2026*

It is helpful for keeping fish healthy.

## Frequently Bought Together

- Seachem StressGuard Slime Coat Protection - Stress and Toxic Ammonia Reducer 250 ml
- Seachem Stability - For Freshwater and Marine Aquariums 250ml
- Seachem Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 250 ml

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-05-20*