--- product_id: 462472725 title: "Toleriane Dermallergo Soothing Night Cream, 48H Hydrating Gel-Moisturiser for Ultra-Sensitive and Allergy-Prone Skin, with Niacinamide and Vitamin B6, 40ml" brand: "la roche-posay" price: "$69.11" currency: USD in_stock: true reviews_count: 13 category: "La Roche Posay" url: https://www.desertcart.us/products/462472725-toleriane-dermallergo-soothing-night-cream-48h-hydrating-gel-moisturiser-ultra store_origin: US region: United States of America --- # Niacinamide & Vitamin B6 soothing 48H deep hydration Microbiome barrier boost Toleriane Dermallergo Soothing Night Cream, 48H Hydrating Gel-Moisturiser for Ultra-Sensitive and Allergy-Prone Skin, with Niacinamide and Vitamin B6, 40ml **Brand:** la roche-posay **Price:** $69.11 **Availability:** ✅ In Stock ## Summary > 🌙 Sleep tight, glow right — soothe, hydrate, and protect your sensitive skin overnight! ## Quick Answers - **What is this?** Toleriane Dermallergo Soothing Night Cream, 48H Hydrating Gel-Moisturiser for Ultra-Sensitive and Allergy-Prone Skin, with Niacinamide and Vitamin B6, 40ml by la roche-posay - **How much does it cost?** $69.11 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/462472725-toleriane-dermallergo-soothing-night-cream-48h-hydrating-gel-moisturiser-ultra) ## Best For - la roche-posay enthusiasts ## Why This Product - Trusted la roche-posay brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Instant Soothing Relief:** Enriched with Niacinamide, Neurosensine, and Vitamin B6 to calm redness, itchiness, and tightness from the first application. - • **Overnight Comfort Ritual:** Wake up to refreshed, calm, and resilient skin every morning, ready to face the day with confidence. - • **Microbiome-Boosting Formula:** Sphingobioma technology restores your skin’s natural defense, reinforcing its protective barrier while you sleep. - • **48-Hour Hydration Powerhouse:** Clinically proven to keep ultra-sensitive skin hydrated day and night, banishing dryness and discomfort. - • **Hypoallergenic & Lightweight:** Minimalist, fragrance-free gel-cream texture absorbs quickly without irritation—perfect for allergy-prone skin. ## Overview La Roche-Posay Toleriane Dermallergo Night Cream is a dermatologist-tested, hypoallergenic gel-moisturiser designed for ultra-sensitive and allergy-prone skin. Featuring advanced microbiome science with Sphingobioma, it restores the skin’s natural barrier and delivers up to 48 hours of hydration. Enriched with Niacinamide, Neurosensine, and Vitamin B6, it instantly soothes redness, itchiness, and tightness. Its lightweight, non-sticky formula absorbs quickly, providing overnight comfort and leaving skin calm, refreshed, and resilient by morning. ## Description Product Description La Roche-Posay Toleriane Dermallergo Night Cream is a soothing and refreshing gel-cream specifically formulated for ultra-sensitive and allergy-prone skin. Clinically proven to hydrate the skin for up to 48 hours, this night moisturiser works night after night to reduce signs of skin sensitivity, such as redness, itchiness, and tightness. Powered by advanced microbiome science, the formula features Sphingobioma—a probiotic-derived fraction that helps restore the skin's microbiome function and reinforces the natural barrier in just one hour. Enriched with Niacinamide, Neurosensine, and Vitamin B6, it immediately relieves discomfort and provides a cooling sensation. The minimalist, hypoallergenic formula is designed to meet the needs of reactive skin, ensuring optimal safety and anti-relapse efficacy. Its non-staining, lightweight texture absorbs quickly, leaving the skin feeling comfortable and calm for a restful night’s sleep. Dermatologically tested and recommended, this night cream is suitable for application on the face, neck, and delicate eye area. At La Roche-Posay, we prioritize high-tolerance ingredients and rigorous testing to provide expert care for problematic skin, helping you achieve a healthy-looking, resilient complexion every morning. Safety Warning For external use only Review: Perfect light moisturiser for sensitive skin - This is a gentle and dependable moisturiser that works well for my sensitive and rosacea-prone skin. The texture is light and it absorbs nicely without feeling heavy or sticky. It leaves the skin feeling soothed, hydrated, and softer throughout the day. I also appreciate that it has no scent, which is exactly what I look for in a product from the Toleriane range. It may not feel rich enough for very dry or peeled skin on its own, but as an everyday moisturiser for sensitive skin I believe it is a very good option for this price. Review: Great for sensitive or allergy prone skin - I really like this moisturiser. I have allergies and very sensitive skin. The La Roche Posay Toleriane range was recommended by my dermatologist and I am very happy with it. There is no smell or fragrance to it, it has a lovely texture for applying and is not too thick. I find it to be soothing and gentle on my skin. It is however fairly sticky to the touch. I don’t like anything sticky on my face but this is sticky to the touch, rather than feeling sticky on my face. It feels as if it is sitting on top of my skin but my skin is lovely and refreshed in the morning. ## Features - NIGHT REPAIR : A soothing gel-cream clinically proven to hydrate skin & reduce signs of sensitivity, including redness & itchiness, night after night. - MICROBIOME SCIENCE : Powered by Sphingobioma to help restore skin microbiome function and reinforce the natural protective barrier while you sleep. - SOOTHING COMPLEX : Enriched with Niacinamide, Neurosensine, and Vitamin B6 to immediately relieve discomfort and provide up to 48 hours of hydration. - HYPOALLERGENIC FORMULA : A minimalist, non-staining gel texture tested on allergic skin to ensure optimal safety for even the most reactive skin types - OVERNIGHT COMFORT : Specifically designed to soothe ultra-sensitive skin prone to tightness, leaving the face feeling refreshed and calm by morning. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B09XJWJM44 | | Active Ingredients | allantoin glycerin niacinamide pentylene glycol polysorbate 20 propanediol sodium hydroxide squalane, niacinamide | | Active ingredients | allantoin glycerin niacinamide pentylene glycol polysorbate 20 propanediol sodium hydroxide squalane, niacinamide Active ingredients allantoin glycerin niacinamide pentylene glycol polysorbate 20 propanediol sodium hydroxide squalane, niacinamide See more | | Age Range Description | Adult | | Age range (description) | Adult | | Benefits | Reduces skin sensitivity, provides 48h hydration, and reinforces the protective barrier overnight. | | Best Sellers Rank | 5,221 in Beauty ( See Top 100 in Beauty ) 28 in Face Night Care Creams | | Brand | La Roche-Posay | | Brand Name | La Roche-Posay | | Country Of Origin | France | | Country as Labeled | Canada | | Customer Reviews | 4.6 out of 5 stars 644 Reviews | | Global Trade Identification Number | 03337875800853 | | Item Dimensions | 36 x 36 x 142 millimetres | | Item Form | Cream | | Item Volume | 40 Millilitres | | Item Weight | 69 Grams | | Item dimensions L x W x H | 36 x 36 x 142 millimetres | | Item volume | 40 Millilitres | | Manufacturer | La Roche Posay | | Manufacturer Part Number | 17954809 | | Material Features | Hypoallergenic | | Model Name | Roche-Posay Dermallergo Nachtcreme, 40 ml | | Model Number | 17954809 | | Number of Items | 1 | | Other Special Features of the Product | Hypoallergenic, Travel Size | | Recommended Uses For Product | Redness | | Scent Name | Cucumber | | Skin Type | Sensitive | | Special Ingredients | Glycerin | | Special feature | Hypoallergenic, Travel Size | | Specific Uses For Product | Apply every evening to a cleansed face, neck, and eye contour area for immediate soothing relief. | | Unit Count | 40 millilitre | ## Product Details - **Age range (description):** Adult - **Brand:** La Roche-Posay - **Item dimensions L x W x H:** 36 x 36 x 142 millimetres - **Item form:** Cream - **Item volume:** 40 Millilitres - **Number of items:** 1 - **Scent:** Cucumber - **Skin type:** Sensitive - **Special feature:** Hypoallergenic, Travel Size ## Images ![Toleriane Dermallergo Soothing Night Cream, 48H Hydrating Gel-Moisturiser for Ultra-Sensitive and Allergy-Prone Skin, with Niacinamide and Vitamin B6, 40ml - Image 1](https://m.media-amazon.com/images/I/61LaIcdY5WL.jpg) ## Questions & Answers **Q: What are the benefits of using the Toleriane Dermallergo Range?** A: The Toleriane Dermallergo range has been designed to calm and soothe sensitive skin prone to redness. Hydrating and nourishing the skin. **Q: What are the ingredients used?** A: Enriched with Dermatologically active ingredients like Sphingobioma and Neurosensins to support the skin microbiome and help reduce skin sensitivity. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Perfect light moisturiser for sensitive skin *by L***S on 5 April 2026* This is a gentle and dependable moisturiser that works well for my sensitive and rosacea-prone skin. The texture is light and it absorbs nicely without feeling heavy or sticky. It leaves the skin feeling soothed, hydrated, and softer throughout the day. I also appreciate that it has no scent, which is exactly what I look for in a product from the Toleriane range. It may not feel rich enough for very dry or peeled skin on its own, but as an everyday moisturiser for sensitive skin I believe it is a very good option for this price. ### ⭐⭐⭐⭐⭐ Great for sensitive or allergy prone skin *by R***L on 8 July 2026* I really like this moisturiser. I have allergies and very sensitive skin. The La Roche Posay Toleriane range was recommended by my dermatologist and I am very happy with it. There is no smell or fragrance to it, it has a lovely texture for applying and is not too thick. I find it to be soothing and gentle on my skin. It is however fairly sticky to the touch. I don’t like anything sticky on my face but this is sticky to the touch, rather than feeling sticky on my face. It feels as if it is sitting on top of my skin but my skin is lovely and refreshed in the morning. ### ⭐⭐⭐⭐⭐ Quality product *by J***U on 30 May 2026* Quality Quality Quality. Ideal for skin prone to redness. Can't fault it ## Frequently Bought Together - La Roche-Posay Toleriane Dermallergo Soothing Night Cream for Sensitive Skin 40ML - La Roche-Posay Toleriane Dermo Milk Facial Cleanser for Sensitive and Allergy-Prone Skin 200ml - La Roche-Posay Toleriane Dermallergo Soothing Cream for Sensitive Skin 40ML --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/462472725-toleriane-dermallergo-soothing-night-cream-48h-hydrating-gel-moisturiser-ultra](https://www.desertcart.us/products/462472725-toleriane-dermallergo-soothing-night-cream-48h-hydrating-gel-moisturiser-ultra) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-07-19*