--- product_id: 428276319 title: "Designs for Health Homocysteine Supreme - Brain & Heart - 60 Capsules" brand: "designs for health" price: "$104.42" currency: USD in_stock: true reviews_count: 5 category: "Designs For Health" url: https://www.desertcart.us/products/428276319-designs-for-health-homocysteine-supreme-brain-and-heart-60-capsules store_origin: US region: United States of America --- # Vegetarian, Non-GMO purity Methylation support for brain clarity Optimizes heart & cardiovascular health Designs for Health Homocysteine Supreme - Brain & Heart - 60 Capsules **Brand:** designs for health **Price:** $104.42 **Availability:** ✅ In Stock ## Summary > 🧬 Elevate your mind & heart health—because your future deserves the best today! ## Quick Answers - **What is this?** Designs for Health Homocysteine Supreme - Brain & Heart - 60 Capsules by designs for health - **How much does it cost?** $104.42 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/428276319-designs-for-health-homocysteine-supreme-brain-and-heart-60-capsules) ## Best For - designs for health enthusiasts ## Why This Product - Trusted designs for health brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Clean & Conscious:** Vegetarian, allergen-free, and free from soy, gluten, and GMOs—pure wellness you can trust - • **Brain & Heart Synergy:** Supports cognitive sharpness and cardiovascular resilience for peak daily performance - • **Clinically-Endorsed Formula:** Trusted by top functional medicine practitioners for reliable, science-backed results - • **Precision Methylation Boost:** Advanced methylated B-complex with L-serine & TMG for superior homocysteine metabolism - • **Tailored Dosage Flexibility:** Effective even at fractional doses, empowering personalized brain & heart health management ## Overview Designs for Health Homocysteine Supreme delivers a potent blend of methylated B vitamins, L-serine, and trimethylglycine (TMG) to optimize homocysteine metabolism, supporting brain clarity, cardiovascular health, and immune function. This vegetarian, non-GMO formula is clinically trusted by functional medicine professionals and designed for superior absorption and personalized dosing, making it a top choice for proactive adults seeking scientifically-backed cognitive and heart wellness. ## Description DFH Customer Favorites Visit the store DFH Customer Favorites Visit the store Shop Magnesium Supplements Visit the store Shop Magnesium Supplements Review: Most effective - Brand is absolutely the best… I have to do blood work every 3 months and my dr prescribes me this brand and results show how effective these supplements are Review: Life / Brain Changer - I have tried 3 different products - I even tried “unmethylated” B12/folate etc. I do carry the MTHFR gene and have high homocysteine. THIS PRODUCT…. Not the others works for me. Though 2 caps is recommended and the dosage on the label is according to that - I can only do 1/4 of ONE capsule a day, but the difference in my life is night and day now. Im 67 and have lived most of my life with migraines, anxiety, depression and in the last couple of years I have been increasingly worried about my brain. My mother was diagnosed with Alzheimer’s at my age and I was mentally feeling worse and worse. I have recently come through a terrible tragedy - the violent death of my 40 year old son. After this happened I was significantly different in my brain. I could not shake the blackness (not just depression) I would wake in the morning and this horrible feeling was with me all day - consistently - over time. I put it down to grief. The first 3 days on this product I felt like I was 20 again. I remembered how I used to have hope and just feel “normal” like this. I realized quickly that I could not take 2 caps a day - I was literally flying mentally and did not sleep the first two nights. Over time I figured out my dosage and I am still in grief but I live every day ‘grounded’ and stable - I have energy and my brain fog is literally gone as is my black feeling in my brain. Anxiety and fear are just not there. I encourage everyone to at least get tested for the MTHFR gene and homocysteine - these tests are now available online without the need for a prescription (at least in California) - easy to find out! God bless you all - I am so thankful to the Lord for this answer to prayer. ## Features - Methylation Support - A modified methylated B complex with L-serine and TMG, which are known to facilitate the efficient metabolism of homocysteine and normal methylation - Promotes Heart & Brain Health - An optimally functioning homocysteine pathway plays a role in biochemical reactions, such as detoxification, healthy immune support, ideal joint and cartilage structure, brain health and cardiovascular health - Premium B Vitamins & TMG for Superior Absorption - Supplies a methylated folate and B12 supplement, along with P5P vitamin B6 and riboflavin. Includes Trimethylglycine to support normal methylation - Vegetarian & Non-GMO - Vegetarian-friendly and made without soy, gluten, GMOs or soy. Take 2 capsules per day with meals or as directed by your health-care practitioner - Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00DJE2WP0 | | Age Range Description | Adult | | Allergen Information | Allergen-Free | | Best Sellers Rank | #81,486 in Health ( See Top 100 in Health ) #2,112 in Multiple Vitamin-Mineral Combination Supplements | | Brand | Designs for Health | | Brand Name | Designs for Health | | Customer Reviews | 4.6 out of 5 stars 299 Reviews | | Diet Type | Vegetarian | | Diet type | Vegetarian | | Dosage Form | Capsule | | Flavor | Unflavored | | Flavour | Unflavored | | Item Dimensions | 5.6 x 5.6 x 10.2 centimeters | | Item Form | Capsule | | Item Weight | 0.04 Ounces | | Item form | Capsule | | Manufacturer | Designs for Health | | Manufacturer Part Number | HYS060-AZ | | Material Type Free | en_AE | | Number of Items | 1 | | Primary Supplement Type | Methylation Support Capsules | | Primary supplement type | Methylation Support Capsules | | Product Benefits | metabolism_improvement, energy_management, antioxidant | | Product benefits | metabolism_improvement, energy_management, antioxidant | | Special Ingredients | B Vitamins, TMG, L-serine | | Specific Uses For Product | Laboratory | | Unit Count | 1.0 Count | ## Product Details - **Brand:** designs for health - **Diet type:** Vegetarian - **Flavour:** Unflavored - **Item form:** Capsule - **Primary supplement type:** Methylation Support Capsules ## Images ![Designs for Health Homocysteine Supreme - Brain & Heart - 60 Capsules - Image 1](https://m.media-amazon.com/images/I/71vlsNh43hL.jpg) ## Questions & Answers **Q: Curious why NAC was removed from the ingredients.** A: Not just NAC, but zinc,B2, serine and chloline dihydrohen citrate **Q: Does the Homocysteine Supreme contain turmeric?** A: No, it contains riboflavin, vit. B-6, folate,vit. B-12, trimethylglycine, and L-serine. additional ingredients are cellulose/microcrystalline cellulose, ascorbyl palmitate, dicalcium phosphate, and silicon dioxide **Q: Designs for health is the product manufacturer - who is the seller on Amazon?** A: It's sold by the Designs for Health store on Amazon. **Q: Does this product contain Bromelain in it?** A: I just checked the label and I don't see Bromelain mentioned anywhere on the label. Hope this helps you. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Most effective *by C***I on 19 July 2026* Brand is absolutely the best… I have to do blood work every 3 months and my dr prescribes me this brand and results show how effective these supplements are ### ⭐⭐⭐⭐⭐ Life / Brain Changer *by W***Y on 6 May 2026* I have tried 3 different products - I even tried “unmethylated” B12/folate etc. I do carry the MTHFR gene and have high homocysteine. THIS PRODUCT…. Not the others works for me. Though 2 caps is recommended and the dosage on the label is according to that - I can only do 1/4 of ONE capsule a day, but the difference in my life is night and day now. Im 67 and have lived most of my life with migraines, anxiety, depression and in the last couple of years I have been increasingly worried about my brain. My mother was diagnosed with Alzheimer’s at my age and I was mentally feeling worse and worse. I have recently come through a terrible tragedy - the violent death of my 40 year old son. After this happened I was significantly different in my brain. I could not shake the blackness (not just depression) I would wake in the morning and this horrible feeling was with me all day - consistently - over time. I put it down to grief. The first 3 days on this product I felt like I was 20 again. I remembered how I used to have hope and just feel “normal” like this. I realized quickly that I could not take 2 caps a day - I was literally flying mentally and did not sleep the first two nights. Over time I figured out my dosage and I am still in grief but I live every day ‘grounded’ and stable - I have energy and my brain fog is literally gone as is my black feeling in my brain. Anxiety and fear are just not there. I encourage everyone to at least get tested for the MTHFR gene and homocysteine - these tests are now available online without the need for a prescription (at least in California) - easy to find out! God bless you all - I am so thankful to the Lord for this answer to prayer. ### ⭐⭐⭐⭐ No child lock *by H***R on 15 January 2026* Helps with anxiety! Good value for money. No child lock on bottle. ## Frequently Bought Together - Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (60 Capsules) - Designs for Health Vitamin D Supreme - Vitamin D 5000 IU with 2000mcg Vitamin K as MK4 for Bone Health, Heart Health & Immune Support - Vitamin D3 Enhanced with GG Supplement (60 Capsules) - Designs for Health N-Acetyl-L-Cysteine - 900mg NAC, Antioxidant Glutathione Precursor - Detox + Workout Recovery Support - Non-GMO + Gluten Free Supplement (120 Capsules) --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/428276319-designs-for-health-homocysteine-supreme-brain-and-heart-60-capsules](https://www.desertcart.us/products/428276319-designs-for-health-homocysteine-supreme-brain-and-heart-60-capsules) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-08-10*