---
product_id: 38488443
title: "Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use"
brand: "ortho"
price: "$47.11"
currency: USD
in_stock: true
reviews_count: 8
url: https://www.desertcart.us/products/38488443-ortho-home-defense-insect-killer-for-indoor-and-perimeter-ready
store_origin: US
region: United States of America
---

# fast-drying, no-fume formula kills 20+ insect types 12-month bug barrier Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use

**Brand:** ortho
**Price:** $47.11
**Availability:** ✅ In Stock

## Summary

> 🛡️ Defend your domain with invisible, long-lasting power!

## Quick Answers

- **What is this?** Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use by ortho
- **How much does it cost?** $47.11 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/38488443-ortho-home-defense-insect-killer-for-indoor-and-perimeter-ready)

## Best For

- ortho enthusiasts

## Why This Product

- Trusted ortho brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Multi-Species Exterminator:** Effectively eliminates over 20 common household insects including ticks, fleas, and scorpions.
- • **Invisible & Odorless Defense:** Invisi-Shield Technology dries clear and emits no fumes, keeping your space fresh and discreet.
- • **Pet & Family Friendly Once Dry:** Re-enter treated areas safely after drying—perfect for homes with kids and pets.
- • **Versatile Indoor & Outdoor Use:** Safe and effective for kitchens, bathrooms, doorways, patios, decks, and foundation perimeters.
- • **Year-Long Shield Against Pests:** Enjoy up to 12 months of continuous protection from ants, roaches, and spiders indoors.

## Overview

Ortho Home Defense Insect Killer offers a powerful, fast-acting spray that kills over 20 types of household insects on contact and creates a 12-month invisible barrier indoors. Its no-fume, quick-dry Invisi-Shield formula is safe for use around kids and pets once dry, making it the ultimate all-season pest control solution for both indoor and perimeter applications.

## Description

Ortho® Home Defense® Insect Killer for Indoor & Perimeter2 kills common household bugs such as ants, beetles, centipedes, cockroaches, crickets, fleas, flies, millipedes, mosquitoes, moths, spiders, stink bugs, ticks, termites, periodical cicadas and more (as listed). This insect killer creates a bug barrier for up to 12 months protection against ants, roaches and spiders indoors on non-porous surfaces. The Invisi-Shield Technology formula gives off no fumes, dries clear and dries fast. Use this pest control product anytime as a preventative treatment or after you see evidence of insect activity for long lasting-control. Apply indoors in kitchens and bathrooms or around doors and windows, and outdoors to the foundation perimeters, patios, decks, garages and wherever insects are a recurring problem. For indoor surfaces, hold sprayer 12 inches from surface being sprayed and apply a 4-inch wide band along the surfaces being treated indoors, or use a 12-inch wide band when applying to a home perimeter. Area should be sprayed until slightly wet without soaking. People and pets may re-enter the treated area once sprays have dried. Trust Ortho® to keep bugs out of your home.

Review: It actually works really well - I had seen ants migrate all the way to my coffee table to eat little bits of food and crumbs from around there. We are kinda messy and don't clean up every day so there was plenty for them to eat. When I was out on the deck I noticed the ants coming from the deck and going to the front door. In the front door there was a piece of candy they were swarming on that must have convinced them to check out the rest of the house. I sprayed them on the candy and they all stopped moving instantly. Then I went outside and sprayed the perimeter of the deck and wherever I saw the ant lines. I finished up by giving a very thick coating around the base of the front door where I knew they came in. Haven't seen an ant line since that day! They even disappeared from my coffee table without any spraying inside. Haven't seen any ants return and not seen any inside. My only issue is that when I was spraying so much a bit got on my hand that I was using for the trigger. The liquid on my hand did not cause any irritation and washed off easily. I'd suggest wearing gloves just in case.
Review: Safe and SUPER Effective - This stuff seriously works! I moved in about three months ago and sprayed around my outside door the first day. Haven’t even had to reapply and I still find bugs that try to climb up but end up dying on their own. It also kills on contact, which is awesome because I hate having to squish them myself. Bonus points for being pet and kid safe once it’s dry, my roommate’s got two dogs, so that’s a must.

## Features

- Ortho Home Defense Insect Killer for Indoor & Perimeter2 kills home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
- This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
- Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
- Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
- This 24 fl. oz. container of Ortho Home Defense Insect Killer for Indoor & Perimeter2 comes with convenient trigger sprayer for easy application

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B01MRUFFG0 |
| Best Sellers Rank | #200,418 in Health & Household ( See Top 100 in Health & Household ) #237 in Indoor Insect & Pest Control Sprays |
| Brand | Ortho |
| Brand Name | Ortho |
| Customer Reviews | 4.4 out of 5 stars 928 Reviews |
| Global Trade Identification Number | 00071549022136 |
| Included Components | Miracle-Gro - 141905 |
| Item Form | Spray |
| Item Type Name | for Indoor & Perimeter 2 Ready-To-Use |
| Item Weight | 8 ounces |
| Liquid Volume | 24 Fluid Ounces |
| Manufacturer | The Scotts Company LLC |
| Model Number | 0221310 |
| Part Number | Miracle-Gro - 141905 |
| Target Species | Insects |
| UPC | 071549022136 |
| Unit Count | 1.0 Count |
| Warranty Description | Warranty |

## Product Details

- **Brand:** Ortho
- **Item Form:** Spray
- **Item Weight:** 0.5 Pounds
- **Liquid Volume:** 24 Fluid Ounces
- **Target Species:** Insects

## Images

![Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use - Image 1](https://m.media-amazon.com/images/I/714A5TemJLL.jpg)
![Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use - Image 2](https://m.media-amazon.com/images/I/71GuNPYhfYL.jpg)
![Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use - Image 3](https://m.media-amazon.com/images/I/81W00Sl-HlL.jpg)
![Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use - Image 4](https://m.media-amazon.com/images/I/71iAhB6C92L.jpg)
![Ortho Home Defense Insect Killer for Indoor & Perimeter Ready-To-Use - Image 5](https://m.media-amazon.com/images/I/81rnxiJzNOL.jpg)

## Questions & Answers

**Q: Is it pet safe?**
A: Yes but I still recommend moving any water or food before you spray.

**Q: Does it kill spotted laternfly?**
A: Indoor and outdoor flying insects, pest, spiders, ants and centipedes.  Good for basements.  Spotted Laternfly 
is an invasive species usually found in China, Taiwan and Vietnam.

**Q: Can this be used for more than just perimeter spray?  Say like the entire floor of the interior of the house?**
A: Yes, this product can be used in indoor and outdoor areas such as kitchens, bathrooms, doors and windows, basements, garages and around the home perimeter. but be careful with pets and children, wait at least 15 minutes for the spray to dry and they may be present in the environment.

**Q: does it kill termites**
A: i do not believe so..we have always used a termite and wood bee spray by bayer.

## Customer Reviews

### ⭐⭐⭐⭐⭐ It actually works really well
*by M***I on July 27, 2024*

I had seen ants migrate all the way to my coffee table to eat little bits of food and crumbs from around there. We are kinda messy and don't clean up every day so there was plenty for them to eat. When I was out on the deck I noticed the ants coming from the deck and going to the front door. In the front door there was a piece of candy they were swarming on that must have convinced them to check out the rest of the house. I sprayed them on the candy and they all stopped moving instantly. Then I went outside and sprayed the perimeter of the deck and wherever I saw the ant lines. I finished up by giving a very thick coating around the base of the front door where I knew they came in. Haven't seen an ant line since that day! They even disappeared from my coffee table without any spraying inside. Haven't seen any ants return and not seen any inside. My only issue is that when I was spraying so much a bit got on my hand that I was using for the trigger. The liquid on my hand did not cause any irritation and washed off easily. I'd suggest wearing gloves just in case.

### ⭐⭐⭐⭐⭐ Safe and SUPER Effective
*by E***N on November 4, 2025*

This stuff seriously works! I moved in about three months ago and sprayed around my outside door the first day. Haven’t even had to reapply and I still find bugs that try to climb up but end up dying on their own. It also kills on contact, which is awesome because I hate having to squish them myself. Bonus points for being pet and kid safe once it’s dry, my roommate’s got two dogs, so that’s a must.

### ⭐⭐⭐⭐ Not great
*by T***S on March 15, 2026*

Didn’t work that great

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-05-17*