---
product_id: 379607225
title: "Isispharma - Neotone Intensive Serum Pigment Spots - Night Cream for Face, Hands and Cleavage - 30ml"
brand: "isispharma"
price: "$57.94"
currency: USD
in_stock: true
reviews_count: 5
url: https://www.desertcart.us/products/379607225-isispharma-neotone-intensive-serum-pigment-spots-night-cream-for-face
store_origin: US
region: United States of America
---

# Patented DEPI-ACT complex for melanin control Nighttime formula for deep skin renewal Clinically proven -43% stain reduction Isispharma - Neotone Intensive Serum Pigment Spots - Night Cream for Face, Hands and Cleavage - 30ml

**Brand:** isispharma
**Price:** $57.94
**Availability:** ✅ In Stock

## Summary

> 🌟 Wake up to flawless skin—because spots don’t stand a chance!

## Quick Answers

- **What is this?** Isispharma - Neotone Intensive Serum Pigment Spots - Night Cream for Face, Hands and Cleavage - 30ml by isispharma
- **How much does it cost?** $57.94 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/379607225-isispharma-neotone-intensive-serum-pigment-spots-night-cream-for-face)

## Best For

- isispharma enthusiasts

## Why This Product

- Trusted isispharma brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Gentle Yet Effective:** Keratolytic ingredients exfoliate surface stains without irritation, perfect for sensitive skin types.
- • **Multi-Area Application:** Designed for face, hands, and cleavage—because your glow deserves full-spectrum care.
- • **Nighttime Ritual Essential:** Use nightly to replace your usual night cream and pair with NEOTONE Radiance SPF50+ for all-day protection and radiance.
- • **Advanced DEPI-ACT Technology:** Patented synergy of depigmenting actives that work before, during, and after stain formation for comprehensive melanin regulation.
- • **Targeted Brown Spot Reduction:** Clinically shown to reduce pigment spots by up to 43%, revealing a clearer, more even complexion.

## Overview

Isispharma Neotone Intensive Serum is a dermatologist-recommended night treatment that visibly reduces brown spots and evens skin tone using a patented DEPI-ACT complex. Clinically proven to reduce pigmentation by up to 43%, it combines keratolytic exfoliation with melanin regulation for multi-area use on face, hands, and cleavage. Ideal for millennials seeking a scientifically advanced, gentle, and effective depigmentation solution as part of their nightly skincare ritual.

## Description

Intensive serum Summer Collection Women, brown spots.

Review: Recommended by a dermatologist for acne scars on the face. Work well over the time
Review: Très bon produit

## Features

- Neotone serum visibly reduces all types of brown spots and uniforms the complexion
- Patented active ingredient complex DEPI-ACT – a synergy of depigmenting active ingredients to act in all stages of staining (before, beyond, afterwards) and regulate melanin production responsible for the formation of stains.
- Keratolytic active ingredients for removing existing stains on the skin surface
- Clinically proven effectiveness: complies with medical reference molecule, with a reduction of stains by up to -43% and optimal tolerances*
- A reference product for Depigmentation Regulations.Directions for use: Use every evening on the visible spots of your face, cleavage and hands, instead of your night care. To maximise efficiency, it is recommended to use in conjunction with NEOTONE Radiance SPF50+ Day Cream.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07RM6KHDB |
| ASIN  | B07RM6KHDB |
| Best Sellers Rank | #54,059 in Beauty ( See Top 100 in Beauty ) #319 in Facial Night Creams |
| Customer reviews | 4.3 4.3 out of 5 stars (425) |
| Date First Available  | 15 July 2019 |
| Department | Women |
| Department  | Women |
| Item model number | 3760269770362 |
| Item model number  | 3760269770362 |
| Language | English |
| Language  | English |
| Manufacturer | Isispharma |
| Manufacturer  | Isispharma |
| Product Dimensions | 5.2 x 3.4 x 13.2 cm; 30 g |
| Product Dimensions  | 5.2 x 3.4 x 13.2 cm; 30 g |

## Product Details

- **Product benefits:** Dark Spot Correction
- **Scent:** Aloe
- **Skin type:** Dry, Normal, Oily
- **Special ingredients:** glycolic_acid, salicylic_acid
- **Use for:** Face

## Images

![Isispharma - Neotone Intensive Serum Pigment Spots - Night Cream for Face, Hands and Cleavage - 30ml - Image 1](https://m.media-amazon.com/images/I/51laBOTiNbL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by L***A on 18 August 2025*

Recommended by a dermatologist for acne scars on the face. Work well over the time

### ⭐⭐⭐⭐ Review
*by M***O on 15 October 2025*

Très bon produit

### ⭐⭐⭐⭐⭐ Review
*by ع***ي on 7 January 2023*

نتائج ممتازه ويشيل البقع الداكنه السوداء بالوجه بس يبيلك تواضب يومياً على الاستخدام

## Frequently Bought Together

- Intensive serum Summer Collection Women
- Isis Pharma Neotone Pigmentation Spots - Serum
- Isis Pharma Isis Pharma Sensylia 24 Hours Cream For Dehydrated Damaged Skin 40Ml

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-03-02*