---
product_id: 32636162
title: "On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube"
brand: "neutrogena"
price: "$20.01"
currency: USD
in_stock: true
reviews_count: 13
category: "Neutrogena"
url: https://www.desertcart.us/products/32636162-on-the-spot-acne-spot-treatment-cream-with-2-5
store_origin: US
region: United States of America
---

# 2.5% Benzoyl Peroxide - fast-acting acne fighter Lightweight Vanishing Formula - invisible & non-greasy 0.75 oz Tube - perfect on-the-go precision On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

**Brand:** neutrogena
**Price:** $20.01
**Availability:** ✅ In Stock

## Summary

> ✨ Clear skin, no compromises — spot treat like a pro! 💼

## Quick Answers

- **What is this?** On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube by neutrogena
- **How much does it cost?** $20.01 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/32636162-on-the-spot-acne-spot-treatment-cream-with-2-5)

## Best For

- neutrogena enthusiasts

## Why This Product

- Trusted neutrogena brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Compact & Convenient:** Travel-friendly 0.75 oz tube fits perfectly in your daily essentials kit.
- • **Oil-Free & Non-Comedogenic:** Keeps pores clear and skin hydrated without clogging or residue.
- • **Gentle Yet Effective Formula:** Targets acne without over-drying or irritating sensitive, dry skin.
- • **Fast-Absorbing Vanishing Cream:** Disappears instantly on skin, allowing seamless use anytime, anywhere.
- • **Clinically Proven Day-1 Results:** See visible pimple reduction starting from the very first application.

## Overview

Neutrogena On-The-Spot Acne Spot Treatment Cream delivers a potent 2.5% benzoyl peroxide formula clinically proven to reduce pimples starting day one. Its lightweight, vanishing cream absorbs quickly without irritation, making it ideal for daily use on dry and acne-prone skin. Packaged in a compact 0.75 oz tube, this oil-free, non-comedogenic treatment offers targeted, on-the-go acne control with a dermatologist-tested formula that kills acne-causing bacteria while maintaining skin comfort.

## Description

Product Description Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% benzoyl peroxide is a clinically proven acne spot treatment for face that helps clear breakouts fast without over-drying, stinging, or burning. This gentle vanishing cream formula absorbs quickly, works invisibly, and is designed for acne-prone and dry skin. The lightweight cream penetrates deep into pores to kill acne bacteria that cause pimples and helps prevent new ones from forming. Suitable for daily use, this acne treatment for face can be applied up to three times a day to affected are-as. The fast working formula helps maintain skin comfort while delivering effective results, making it an ideal choice for those seeking a gentle yet effective acne spot treatment. The 0.75 oz tube is perfect for targeted application and on-the-go use. This acne spot treatment cream is formulated to address the needs of those with acne-prone and dry skin, providing a vanishing cream that absorbs quickly and leaves no residue. The clinically proven formula is designed to be gentle enough for daily use, helping to reduce the appearance of pimples and helps prevent new breakouts. With its lightweight, non-greasy texture, this acne treatment for face fits seamlessly into your skincare routine. The vanishing cream formula ensures that the treatment works invisibly, so you can use it throughout the day without noticeable residue. Neutrogena On-The-Spot Acne Spot Treatment Cream is an essential addition to your personal care products, delivering targeted acne control and supporting your skin care goals. Trust in a product that combines the power of benzoyl peroxide with a gentle, cream base for effective, visible results. Brand Story By Neutrogena

Review: Best spot treatment for the occasional pimple! - This is the best acne spot treatment I’ve ever used. I always keep a fresh tube on hand. It works quickly and the 2.5% benzoyl peroxide is effective but a lot gentler than most acne products. The tube is designed with a small opening which is great for dispensing only the tiny amount needed to spot treat. Follow directions, be patient and you’ll be very satisfied with the results.
Review: Great stuff. Not harsh and very effective. - This stuff is pretty darn amazing on pimples and limited breakouts. What I have found is....I'm too damn old to be getting pimples. Thanks, peri-menopause. But, if I wake up and my skin has decided to pull this nonsense on me, I simply dab some on-the-spot, on that spot. By evening, I may need a second dab but, in no time, the pimple has dried and all-but disappeared and what I find remains is typically, a dot of dry skin where a pimple once was. Wash that off with your face washing habit and, viola. No more pimple in short order. My youngest child uses it as well, with similar, efficient results. Great stuff and not at all harsh, in our experience. We love it.

## Features

- Acne spot treatment: Targets pimples with gentle 2.5% benzoyl peroxide; Effectively treats breakouts without over-drying or irritating skin, making it ideal for daily use on acne-prone and dry skin types
- Vanishing cream formula: Lightweight, fast-absorbing, and invisible on skin; This acne treatment for face delivers lasting results and can be used up to three times daily for clearer, healthier-looking skin
- Clinically proven results: Clears skin starting day 1 without stinging or burning; Dermatologist-tested formula goes deep down into pores to kill the acne bacteria that can cause pimples
- Gentle for dry and acne-prone skin: Perfect for those seeking effective acne care without over dry-ing or discomfort
- Neutrogena On-The-Spot Acne Spot Treatment cream is an effective acne treatment for face in a convenient 0.75 oz tube

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00UOLIOC6 |
| Active Ingredients | benzoyl_peroxide |
| Best Sellers Rank | #2,134 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #72 in Facial Serums |
| Brand | Neutrogena |
| Brand Name | Neutrogena |
| Container Type | Tube |
| Customer Reviews | 4.6 out of 5 stars 4,191 Reviews |
| Global Trade Identification Number | 00070501017906, 00883153364607 |
| Item Form | Cream |
| Item Volume | 1.6 Fluid Ounces |
| Item Weight | 0.1 Pounds |
| Manufacturer | Kenvue |
| Manufacturer Part Number | PPAX1208410 |
| Material Features | oil-free and non-comedogenic |
| Model Number | 2620649002 |
| Package Size Name | 0.75 Oz. |
| Product Benefits | Hydrating |
| Scent | Unscented |
| Scent Name | Unscented |
| Size | 0.75 Ounce (Pack of 1) |
| Skin Type | Dry |
| Special Ingredients | Benzoyl Peroxide |
| Target Use Body Part | Face |
| UPC | 070501017906 |

## Product Details

- **Brand:** Neutrogena
- **Item Form:** Cream
- **Product Benefits:** Hydrating
- **Scent:** Unscented
- **Skin Type:** Dry

## Images

![On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube - Image 1](https://m.media-amazon.com/images/I/71xbXocZVcL.jpg)
![On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube - Image 2](https://m.media-amazon.com/images/I/71WItfHKVqL.jpg)
![On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube - Image 3](https://m.media-amazon.com/images/I/71m9+PxWxsL.jpg)
![On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube - Image 4](https://m.media-amazon.com/images/I/71PJuzPw3ZL.jpg)
![On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube - Image 5](https://m.media-amazon.com/images/I/71Whsa66xiL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Can I leave this on overnight?**
A: Sure. Put it on and leave it on anytime. There's no color and it dries the pimple but not the surrounding skin. Great stuff.

**Q: Can you use this on your thighs?**
A: I would say yes!

**Q: Is it suppose to make your skin warm/hot ?**
A: I didnt have that experience and neither did my sister. I definitely dont think you're supposed to uave that reaction in my opinion.

**Q: how fast does does it take to completely erase your acne?**
A: I used it for 10 years and it worked really good, then they changed the ingredients.  It made my face itch and breakout.  I dont recommend this product. I use Dr Song 2.5 benzole peroxide gel. Fries clear and does the job.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Best spot treatment for the occasional pimple!
*by V***B on May 8, 2026*

This is the best acne spot treatment I’ve ever used. I always keep a fresh tube on hand. It works quickly and the 2.5% benzoyl peroxide is effective but a lot gentler than most acne products. The tube is designed with a small opening which is great for dispensing only the tiny amount needed to spot treat. Follow directions, be patient and you’ll be very satisfied with the results.

### ⭐⭐⭐⭐⭐ Great stuff. Not harsh and very effective.
*by S***D on March 9, 2026*

This stuff is pretty darn amazing on pimples and limited breakouts. What I have found is....I'm too damn old to be getting pimples. Thanks, peri-menopause. But, if I wake up and my skin has decided to pull this nonsense on me, I simply dab some on-the-spot, on that spot. By evening, I may need a second dab but, in no time, the pimple has dried and all-but disappeared and what I find remains is typically, a dot of dry skin where a pimple once was. Wash that off with your face washing habit and, viola. No more pimple in short order. My youngest child uses it as well, with similar, efficient results. Great stuff and not at all harsh, in our experience. We love it.

### ⭐⭐⭐⭐⭐ Neutrogena recommend
*by K***E on February 16, 2026*

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube I’ve been using this On-the-Spot acne treatment from Neutrogena for a while now, and I’m really impressed with the results. The cream is thin and easy to apply, and it absorbs quickly without leaving my skin greasy. I’m already used to using it, and I’ve honestly never been disappointed any day I apply it on any small imperfection I have. It helps dry out pimples fast while still being gentle on my skin. A small amount goes a long way, and I would definitely recommend it to anyone dealing with breakout☺️

## Frequently Bought Together

- Neutrogena On-The-Spot Acne Spot Treatment with 2.5% Benzoyl Peroxide Acne Treatment Medication to Treat Face Acne, Gentle Benzoyl Peroxide Pimple Cream for Acne Prone Skin Care,.75 oz
- Mighty Patch™ Original patch from Hero Cosmetics – The #1 Hydrocolloid Acne Pimple Patch for Shrinking Zits and Whiteheads in 1 use; Nighttime Spot Stickers for Face and Skin (36 Count)
- Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 10% Benzoyl Peroxide Acne Treatment Medication, Pimple Cream for Acne Prone Skin Care, 1 oz

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-05-13*