--- product_id: 326301694 title: "Douxo S3 PYO Chlorhexidine Shampoo For Dogs, Medicated Shampoo Antibacterial & Antiseptic, Yeast Infection Treatment for Dogs & Cats, Clinically Proven, 16.9 fl oz" brand: "douxo" price: "$103.21" currency: USD in_stock: true reviews_count: 13 category: "Douxo" url: https://www.desertcart.us/products/326301694-douxo-s3-pyo-chlorhexidine-shampoo-for-dogs-medicated-shampoo-antibacterial store_origin: US region: United States of America --- # Vet #1 recommended antiseptic shampoo Clinically proven in 7 days 0.5% Ophytrium for skin hydration & soothing Douxo S3 PYO Chlorhexidine Shampoo For Dogs, Medicated Shampoo Antibacterial & Antiseptic, Yeast Infection Treatment for Dogs & Cats, Clinically Proven, 16.9 fl oz **Brand:** douxo **Price:** $103.21 **Availability:** βœ… In Stock ## Summary > πŸ•β€πŸ¦Ί Elevate your pet’s skin health game β€” because they deserve vet-grade care! ## Quick Answers - **What is this?** Douxo S3 PYO Chlorhexidine Shampoo For Dogs, Medicated Shampoo Antibacterial & Antiseptic, Yeast Infection Treatment for Dogs & Cats, Clinically Proven, 16.9 fl oz by douxo - **How much does it cost?** $103.21 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/326301694-douxo-s3-pyo-chlorhexidine-shampoo-for-dogs-medicated-shampoo-antibacterial) ## Best For - douxo enthusiasts ## Why This Product - Trusted douxo brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Multi-Pet Friendly:** Perfectly formulated for both dogs and cats with sensitive skin. - β€’ **Vet-Trusted Formula:** Top recommended antiseptic shampoo for bacterial & yeast infections. - β€’ **Natural Skin Soother:** Infused with 0.5% Ophytrium to calm irritation and lock in moisture. - β€’ **Clean & Safe Ingredients:** Free from soaps, sulfates, parabens, dyes, nanoparticles & phthalates. - β€’ **Fast-Acting Clinical Power:** See visible skin relief in just 7 days, backed by science. ## Overview Douxo S3 PYO Chlorhexidine Shampoo is a clinically proven, vet-recommended antiseptic shampoo designed to treat bacterial and yeast skin infections in dogs and cats. Enriched with 0.5% natural Ophytrium, it soothes irritated skin while hydrating deeply. Free from harsh chemicals like soaps, sulfates, parabens, and dyes, this hypoallergenic formula delivers fast, effective relief and supports healthy skin in just 7 days. ## Description DOUXO S3 PYO Dog Shampoo helps support dogs with bacterial and yeast skin infections that are responsive to chlorhexidine by providing antiseptic cleansing and hydrating the skin. Formulated with chlorhexidine. Vet-recommended and free from soaps, sulfates, parabens, colorants, nanoparticles, and phthalates. For best results, pair with DOUXO S3 PYO Dog Mousse and Wipes. Review: Best ever for yeasty shih tzu - As a professional groomer I can't recommend this product enough. In Dec we got a new Shih Tzu pup who was very yeasty. First thing we did is change her feed, and bathed her in every to my knowledge for yeast for the next 5 months, nothing worked and I mean nothing. As a groomer I didn't want her on the vicious cycle of steroids and antibiotics that only temporarily give her relief. After much research I took the 40.00 leap as a last ditch effect before letting the Vet medicate her. I kid you not the 1st bath and she was clearing up. You have to take your time and really work the product into the coat allowing to set for a bit before rinsing. I do 2 lathers letting each set for 10 mins. Rinse extra well. Today was her 3 bath in this amazing product. No itching, no yeasty musty smell and no itching during her dryer time. The smell is nice, pricy but a little goes a long way and worth every cent. I honestly need it in gallon size for my grooming room. Review: Amazing! - After many vet visits and different products used this is the only thing that helped my boo girl with her skin allergies. She smells better, hair is growing back, it’s a little brutal watching your dog shiver for the time you have to let it sit lathered on them but oh so worth it for a healthy pup. My dog looks like my dog again and she’s acting like herself too! Worked wonders for her. Leaves her soft and beautiful. ## Features - CLINICALLY PROVEN RESULTS: DOUXO S3 is proven to show results in as soon as 7 days. - ANTISEPTIC CHLORHEXIDINE DOG SHAMPOO FOR YEAST AND BACTERIAL SKIN INFECTIONS: Formulated for dogs with bacterial or yeast skin infections – DOUXO S3 PYO chlorhexidine dog shampoo provides an antiseptic cleansing while hydrating the skin. - #1 TOPICAL BRAND RECOMMENDED BY VETS: Confirmed by veterinary and scientific expertise. DOUXO provides the best and the safest care for your pet. - ENRICHED WITH OPHYTRIUM: Contains 0.5% Ophytrium, a purified, natural ingredient that helps soothe irritated skin and support skin hydration. - FREE FROM soaps, sulphates, parabens, colorants, nanoparticles, and phthalates. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0949RKDYC | | Allergen Information | Hypoallergenic | | Best Sellers Rank | #348 in Pet Supplies ( See Top 100 in Pet Supplies ) #3 in Dog Shampoos | | Brand | Douxo | | Brand Name | Douxo | | Customer Reviews | 4.7 out of 5 stars 8,215 Reviews | | Included Components | Shampoo | | Item Form | Shampoo | | Item Type Name | Shampoos & Conditioners | | Item Weight | 1.1 pounds | | Liquid Volume | 500 ml | | Manufacturer | Douxo S3 | | Manufacturer Part Number | D98420E | | Material Type Free | Soap Free, Sulfate Free, Paraben Free, Dye Free, Nanoparticle Free | | Model Number | D98420E | | Pet Type | Cat, Dog | | Product Benefits | Anti-Fungal | | Recommended Uses For Product | Irritated Skin,Moisturizing | | Scent | coconut and vanilla | | Scent Name | coconut and vanilla | | Special Ingredients | chlorhexidine, ophytrium | | Target Species | dog, cat | | UPC | 850002593433 | | Unit Count | 1 Count | ## Product Details - **Brand:** Douxo - **Material Type Free:** Soap Free, Sulfate Free, Paraben Free, Dye Free, Nanoparticle Free - **Product Benefits:** Anti-Fungal - **Recommended Uses For Product:** Irritated Skin,Moisturizing - **Scent:** coconut and vanilla ## Images ![Douxo S3 PYO Chlorhexidine Shampoo For Dogs, Medicated Shampoo Antibacterial & Antiseptic, Yeast Infection Treatment for Dogs & Cats, Clinically Proven, 16.9 fl oz - Image 1](https://m.media-amazon.com/images/I/61yhoJoV-IL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: What happened to the original formula that had these active ingredients: chlorhexadine 3%, climbazole .5%, phytosphingosine salicyloyl .05%??????** A: I talked to my Dog's Allergy Vet's office recently about this. They told me they reformulated this and took out some ingredients due to some Dog's having a reaction to it. Also, I don't like it and its nothing like the original formula. It doesn't suds up and I had to use more than double the amount the directions said on my 8 lb dog. **Q: I'm using the other brand of Douxo for my dog's skin allergies. How does this compare to the other Douxo?** A: This product is specifically designed to relieve bacterial or fungal skin infections. Specifically, it helps to soothe irritated skin. If your dog has skin allergies, this particular shampoo could be a good choice since it is the #1 non-prescription topical brand used and recommended by U.S. veterinarians. **Q: Why doesn't it say antifungal any more? it still says it in the description but no longer on the bottle? why?** A: Mine says antifungal anticeptic **Q: Who can i message that sells this product?** A: We do :) ## Customer Reviews ### ⭐⭐⭐⭐⭐ Best ever for yeasty shih tzu *by C***E on July 30, 2026* As a professional groomer I can't recommend this product enough. In Dec we got a new Shih Tzu pup who was very yeasty. First thing we did is change her feed, and bathed her in every to my knowledge for yeast for the next 5 months, nothing worked and I mean nothing. As a groomer I didn't want her on the vicious cycle of steroids and antibiotics that only temporarily give her relief. After much research I took the 40.00 leap as a last ditch effect before letting the Vet medicate her. I kid you not the 1st bath and she was clearing up. You have to take your time and really work the product into the coat allowing to set for a bit before rinsing. I do 2 lathers letting each set for 10 mins. Rinse extra well. Today was her 3 bath in this amazing product. No itching, no yeasty musty smell and no itching during her dryer time. The smell is nice, pricy but a little goes a long way and worth every cent. I honestly need it in gallon size for my grooming room. ### ⭐⭐⭐⭐⭐ Amazing! *by S***Y on August 11, 2026* After many vet visits and different products used this is the only thing that helped my boo girl with her skin allergies. She smells better, hair is growing back, it’s a little brutal watching your dog shiver for the time you have to let it sit lathered on them but oh so worth it for a healthy pup. My dog looks like my dog again and she’s acting like herself too! Worked wonders for her. Leaves her soft and beautiful. ### ⭐⭐⭐⭐⭐ This product works!! Expensive but oh so worth it!🐢❀️🐢 *by A***N on August 26, 2026* My poor English bulldog Oakly was scratching so bad and we HAD to try this and do it quickly I ordered this after doing research and got it overnight , very fast delivery! After washing her , which lathered up very well we crossed our fingers and prayed it would help her, after about an hour we noticed the scratching was less thank God and after a few more hours past the scratching became very far and between , down to none! It worked!! Make sure when washing that you let it sit on your fur baby atleast 5 to 10 minutes before rinsing, that's where the magic happens! I'm so grateful for this product oh and did I mention the wonderful smell, it's not to strong, kinda vanilla scent. Will definitely buy again but use sparingly because it is expensive and the bottle is small but oh so worth it for your baby.🐢❀️🐢 ## Frequently Bought Together - Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 16.9 fl. oz. (500mL) - Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL) - Douxo S3 Pyo Pads, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 30 Pads --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/326301694-douxo-s3-pyo-chlorhexidine-shampoo-for-dogs-medicated-shampoo-antibacterial](https://www.desertcart.us/products/326301694-douxo-s3-pyo-chlorhexidine-shampoo-for-dogs-medicated-shampoo-antibacterial) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-09-08*