---
product_id: 317470185
title: "S3 Calm Dog Shampoo for Itchy Skin Relief, Dog Shampoo for Allergies and Itching, Soothes Itchy, Irritated or Allergic Skin For Dogs and Cats, 6.7 fl oz"
brand: "douxo"
price: "$53.87"
currency: USD
in_stock: true
reviews_count: 13
category: "Douxo"
url: https://www.desertcart.us/products/317470185-s3-calm-dog-shampoo-for-itchy-skin-relief-dog-shampoo
store_origin: US
region: United States of America
---

# Clinically proven relief in 7 days 0.75% natural Ophytrium for soothing hydration Vet-recommended #1 topical brand S3 Calm Dog Shampoo for Itchy Skin Relief, Dog Shampoo for Allergies and Itching, Soothes Itchy, Irritated or Allergic Skin For Dogs and Cats, 6.7 fl oz

**Brand:** douxo
**Price:** $53.87
**Availability:** ✅ In Stock

## Summary

> 🐕‍🦺 Calm the itch, reclaim the cuddle time!

## Quick Answers

- **What is this?** S3 Calm Dog Shampoo for Itchy Skin Relief, Dog Shampoo for Allergies and Itching, Soothes Itchy, Irritated or Allergic Skin For Dogs and Cats, 6.7 fl oz by douxo
- **How much does it cost?** $53.87 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/317470185-s3-calm-dog-shampoo-for-itchy-skin-relief-dog-shampoo)

## Best For

- douxo enthusiasts

## Why This Product

- Trusted douxo brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Gentle:** Free from soaps, sulfates, parabens, colorants, nanoparticles, and phthalates—pure care for sensitive skin.
- • **Fast-Acting Relief:** Clinically proven to calm itchy skin in just 7 days—don’t let discomfort linger.
- • **Multi-Pet Friendly:** Perfect for both dogs and cats with sensitive or allergic skin, supporting overall skin comfort.
- • **Nature-Powered Care:** Enriched with 0.75% Ophytrium, a natural ingredient that soothes irritation and boosts skin hydration.
- • **Vet-Trusted Formula:** Topical brand #1 recommended by vets, ensuring safe and effective allergy and itch relief.

## Overview

Douxo S3 Calm Dog Shampoo is a vet-recommended, hypoallergenic formula clinically proven to soothe itchy, irritated, and allergic skin in dogs and cats within 7 days. Featuring 0.75% natural Ophytrium, it hydrates and calms sensitive skin without harsh chemicals, making it the trusted choice for pet owners seeking fast, effective relief and healthier coats.

## Description

Is your dog constantly scratching, licking, chewing, or biting? These may be signs of skin allergies. DOUXO S3 CALM Dog Shampoo helps soothe itchy, irritated, or allergic skin in as soon as 7 days. Vet-recommended and free from soaps, sulfates, parabens, colorants, nanoparticles, and phthalates. For best results, pair with DOUXO S3 CALM Dog Mousse.

Review: Itchy Issues Tamed - Good quality shampoo . I specifically bought for my dog’s itchy skin. I read the reviews too regarding others dealing with dogs itchy skin issues. I think it’s expensive for this small size bottle so I’m using it once a week on my chihuahua. He seemed to relax after the bath . Not as much itching. A little amount lathered up well. I left it on 15 minutes bed rinsing like the directions specified. Smells nice not strong at all. Super soft fur. He’s a short hair chihuahua and doesn’t shed a lot of fur. I bought the small bottle to try before I do the subscribe and save with the bigger size.I recommend for soft fur and itchy skin issues.
Review: This stuff WORKS - Kept my dog from itching 24/7. This really does soothe the skin and allows for healing. My dog had a horrible rash on his neck from scratching and this allowed it time to heal while we switched foods. Make SURE you read the instructions before use- it has to sit on the skin for it to work. It is worth the price. I've only had to use it twice and it works instantly. Great product! lathers up like regular shampoo, smells great, and leaves the skin and coat skiny and healthy.

## Features

- CLINICALLY PROVEN RESULTS: DOUXO S3 is proven to show results in as soon as 7 days.
- DOG SHAMPOO FOR ALLERGIES AND ITCHING: Formulated for dogs with sensitive or allergic skin, including those showing signs such as scratching, licking, chewing, or biting — DOUXO S3 CALM dog shampoo helps soothe itchy skin and support skin comfort.
- #1 TOPICAL BRAND RECOMMENDED BY VETS: Confirmed by veterinary and scientific expertise. DOUXO provides the best and the safest care for your pet.
- ENRICHED WITH OPHYTRIUM: Contains 0.75% Ophytrium, a purified, natural ingredient that helps soothe irritated skin and support skin hydration.
- FREE FROM soaps, sulphates, parabens, colorants, nanoparticles, and phthalates.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B09478KGJZ |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #966 in Pet Supplies ( See Top 100 in Pet Supplies ) #8 in Dog Shampoos |
| Brand | Douxo |
| Brand Name | Douxo |
| Customer Reviews | 4.6 out of 5 stars 4,108 Reviews |
| Included Components | Shampoo |
| Item Form | Liquid |
| Item Type Name | Shampoos & Conditioners |
| Liquid Volume | 6.7 fluid ounces |
| Manufacturer | Douxo S3 |
| Manufacturer Part Number | D98110P |
| Material Type Free | Hypoallergenic |
| Model Number | D98110P |
| Number of Packs | 1 |
| Pet Type | Cat, Dog |
| Product Benefits | Anti-Itch |
| Recommended Uses For Product | Itchy |
| Scent | Fresh, Sweet |
| Scent Name | Fresh, Sweet |
| Special Ingredients | Ophytrium |
| Target Species | dog, cat |
| UPC | 850002593389 |
| Unit Count | 1 Count |

## Product Details

- **Brand:** Douxo
- **Material Type Free:** Hypoallergenic
- **Product Benefits:** Anti-Itch
- **Recommended Uses For Product:** Itchy
- **Scent:** Fresh, Sweet

## Images

![S3 Calm Dog Shampoo for Itchy Skin Relief, Dog Shampoo for Allergies and Itching, Soothes Itchy, Irritated or Allergic Skin For Dogs and Cats, 6.7 fl oz - Image 1](https://m.media-amazon.com/images/I/61fIkdZDoiL.jpg)

## Available Options

This product comes in different **Size** options.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Itchy Issues Tamed
*by J***O on July 15, 2026*

Good quality shampoo . I specifically bought for my dog’s itchy skin. I read the reviews too regarding others dealing with dogs itchy skin issues. I think it’s expensive for this small size bottle so I’m using it once a week on my chihuahua. He seemed to relax after the bath . Not as much itching. A little amount lathered up well. I left it on 15 minutes bed rinsing like the directions specified. Smells nice not strong at all. Super soft fur. He’s a short hair chihuahua and doesn’t shed a lot of fur. I bought the small bottle to try before I do the subscribe and save with the bigger size.I recommend for soft fur and itchy skin issues.

### ⭐⭐⭐⭐⭐ This stuff WORKS
*by T***M on July 16, 2026*

Kept my dog from itching 24/7. This really does soothe the skin and allows for healing. My dog had a horrible rash on his neck from scratching and this allowed it time to heal while we switched foods. Make SURE you read the instructions before use- it has to sit on the skin for it to work. It is worth the price. I've only had to use it twice and it works instantly. Great product! lathers up like regular shampoo, smells great, and leaves the skin and coat skiny and healthy.

### ⭐⭐⭐⭐⭐ My dog’s sensitive skin loves this shampoo
*by J***I on August 16, 2026*

I’ve been extremely happy with DOUXO S3 CALM Dog Shampoo! It lathers nicely, rinses out easily, and feels gentle on my dog’s skin. I especially like that it’s made for sensitive, itchy, or irritated skin and doesn’t have an overpowering fragrance. She used to get hot spots, and no longer has issues with those. After bathing, my dog’s coat feels soft and clean without their skin feeling overly dry. It’s a great option for dogs who need something a little gentler than a standard shampoo. A little goes a long way, too, which helps make the bottle last.

## Frequently Bought Together

- Douxo S3 Calm Shampoo, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 6.7 fl. oz. (200mL)
- Douxo S3 Calm Mousse, Contains 0.75% Ophytrium, Soothing, For Itchy, Irritated or Allergic Skin, For Dogs and Cats, 5.1 fl. oz. (150mL)
- Douxo S3 Pyo Pads, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 30 Pads

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-09-05*