--- product_id: 247862108 title: "Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml" brand: "n1o1" price: "$218.73" currency: USD in_stock: true reviews_count: 6 category: "N1 O1" url: https://www.desertcart.us/products/247862108-nitric-oxide-activating-serum-with-antioxidants-hydrating-serum-for-face store_origin: US region: United States of America --- # 20% Vitamin C antioxidant boost Hydrates & moisturizes deeply Nitric Oxide activates collagen Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml **Brand:** n1o1 **Price:** $218.73 **Availability:** ✅ In Stock ## Summary > ✨ Glow like you mean it — the serum your skin’s been craving! ## Quick Answers - **What is this?** Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml by n1o1 - **How much does it cost?** $218.73 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/247862108-nitric-oxide-activating-serum-with-antioxidants-hydrating-serum-for-face) ## Best For - n1o1 enthusiasts ## Why This Product - Trusted n1o1 brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Gentle for All:** Safe and effective for dry, oily, sensitive, and normal skin types - • **Age-Defying Formula:** Smooths wrinkles and minimizes pores with nitric oxide activation - • **Brighten & Even Tone:** 20% Vitamin C reduces dark spots and balances skin tone - • **Hydration Powerhouse:** Locks in moisture for supple, glowing skin all day long - • **Effortless Glow Ritual:** Just one pump per use, day or night, for up to 70 applications ## Overview This 1 fl oz Nitric Oxide Activating Serum combines a potent 20% Vitamin C antioxidant complex with nitric oxide to hydrate, reduce wrinkles, minimize pores, and brighten skin tone. Suitable for all skin types, it supports collagen production and fights oxidative stress without harsh chemicals. With up to 70 easy applications per bottle, it’s a professional-grade skincare essential that visibly improves texture, fades dark spots, and delivers a youthful, radiant complexion. ## Description desertcart.com: Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml : Beauty & Personal Care Review: Removed my scar, despite infrequent use - Three years ago, I cut my face right in between my eyebrows. I got left with a 1/4” scar that ran deep, extended my wrinkle and gave me a permanently worried look. It got worse over time. My trusty moisturizer helped everywhere, except for the scar. The need to do something overcame my skepticism about nitric oxide, so I decided to give it a chance. I had no expectations. The instructions recommend daily application. I applied about twice a week. For a couple weeks, there was no change. Maybe a month later I noticed the scar is no longer joined to my eyebrow wrinkle, reducing my angry, worried look. I began applying every other day and after a few more weeks, the scar is now flat and only visible within a few feet distance. By flat I mean no longer deep, almost completely flush with the skin, with a very slightly discolored center. The scar basically shrank in size and almost disappeared optically. My wrinkles also improved substantially. I now believe that the scar will disappear completely with another few weeks of frequent use. I started to apply all over my face and neck, since the minimum dose is large enough. I’m now administering to whoever asks: seniors, youth, children, … whoever has skin damage. The cream itself clogs pores a little so I shower it off at the end of the day. It’s not suitable for wearing light colors as it can stain them yellow. I wish it came in glass instead of plastic. I thought I’d keep my scar for the rest of my life, looking progressively angrier as I age. And yet, here we are - I’ve reversed three years of skin damage. Thank you Dr. Nathan Bryer! Review: It works! - This is my no. 1 go-to serum. I have been using it since 2021 and have seen a great improvement in the smoothness of my skin, particularly around my eyes. One morning in 2021, I looked in the mirror and it was like somebody pulled a switch. The delicate skin around the eyes, that had been fairly smooth, suddenly sagged and looked baggy. None of my existing products did anything. Fortunately, I saw a TV commercial for the N1O1 serum and decided to give it a try. Since I am a woman of a certain age, I followed the instructions and began using it twice a day, with emphasis on the eye area. I have sensitive skin around the eyes and on the cheeks. There was, and still is, no irritation. Within about 3 days, there was improvement. The skin looked much more lifted. The whole eye area began to smooth out. In fact, since I was applying the serum over my whole face, my facial skin began to look smoother. Pores looked smaller, and the skin tone was more even. The effect of the serum seems to build over time. I continue to use the serum every day and am very pleased with the results. ## Features - Hydrating And Moisturizing: Our moisturizing face serum combines Nitric Oxide with Vitamin C to bring you a facial serum that will help support smooth, supple and soft skin without relying on any harsh chemicals or additives for day to day skincare. - Brighter And Smoother Skin: Our facial skin care serum with Nitric Oxide helps support collagen, hydration, and nutrient flow to your skin to help reduce the visibility of fine lines, dark spots, and other signs of aging without relying on any harsh chemicals or additives. - Even Skin Tone Support: This skin brightening serum contains 20% Vitamin C that not only helps moisturize the skin but also helps provide antioxidant support to help reduce oxidative stress by helping neutralize free-radicals to support an even and brighter skin tone. - Suitable For All Skin Types: The vitamin C face serum utilizes Nitric Oxide along with a balanced formula to help support the skin without relying on any harsh chemicals. N1O1 nitric oxide and Vitamin C serum is suitable for dry, oily, normal, and sensitive skin to offer gentle support. - Simple To Use: Each bottle of N101 activating serum can provide up to 70 applications Simply apply a single pump of serum to your palm, gently massage it onto your face and neck, and let it rest for 1-2 minutes. Our vitamin C serum can be applied both during the day and night. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B08LNTJZST | | Best Sellers Rank | #41,468 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #878 in Facial Serums | | Customer Reviews | 4.1 4.1 out of 5 stars (303) | | Item model number | n1o1 | | Manufacturer | Pneuma Nitric Oxide | | Product Dimensions | 6 x 2 x 2 inches; 11.99 ounces | | UPC | 608597658903 | ## Product Details - **Product Benefits:** Anti-Aging - **Scent:** Fragrance Free - **Skin Type:** All - **Special Ingredients:** Antioxidants, Vitamin C, Vitamin E - **Use for:** Face ## Images ![Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml - Image 1](https://m.media-amazon.com/images/I/519vaxPub-L.jpg) ## Questions & Answers **Q: What color is the serum supposed to be directly out of the bottle?** A: The bottle is a dual chamber system - one side of the bottle contains vitamin C, the other side contains liquid nitric oxide. When you use one pump from each side of the bottle, and mix the drops together in the palm of your hand, the vitamin C acts as the activating ingredient to activate the nitric oxide. The nitric oxide serum is clear, the vitamin C can be an amber color. **Q: Should I use hyaluronic acid in addition to this, or does this replace hyaluronic acid?** A: Thank you for reaching out! You should use Hyaluronic Acid after using our Nitric Oxide Activating Serum. The serum help with the absorption of the HA...and will actually boost it! Hope this helps! **Q: What percentage of nitric oxide?** A: Thank you for asking! The serum is a dual chamber bottle that contains nitrite in one chamber and Vitamin C in the other. The vitamin C is the activating agent which when mixed with the nitrite creates nitric oxide gas. The mixture is 100% nitric oxide. Hope this helps. **Q: is it animal tested?** A: No, our products are never animal tested. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Removed my scar, despite infrequent use *by F***R on August 26, 2025* Three years ago, I cut my face right in between my eyebrows. I got left with a 1/4” scar that ran deep, extended my wrinkle and gave me a permanently worried look. It got worse over time. My trusty moisturizer helped everywhere, except for the scar. The need to do something overcame my skepticism about nitric oxide, so I decided to give it a chance. I had no expectations. The instructions recommend daily application. I applied about twice a week. For a couple weeks, there was no change. Maybe a month later I noticed the scar is no longer joined to my eyebrow wrinkle, reducing my angry, worried look. I began applying every other day and after a few more weeks, the scar is now flat and only visible within a few feet distance. By flat I mean no longer deep, almost completely flush with the skin, with a very slightly discolored center. The scar basically shrank in size and almost disappeared optically. My wrinkles also improved substantially. I now believe that the scar will disappear completely with another few weeks of frequent use. I started to apply all over my face and neck, since the minimum dose is large enough. I’m now administering to whoever asks: seniors, youth, children, … whoever has skin damage. The cream itself clogs pores a little so I shower it off at the end of the day. It’s not suitable for wearing light colors as it can stain them yellow. I wish it came in glass instead of plastic. I thought I’d keep my scar for the rest of my life, looking progressively angrier as I age. And yet, here we are - I’ve reversed three years of skin damage. Thank you Dr. Nathan Bryer! ### ⭐⭐⭐⭐⭐ It works! *by D***. on April 4, 2023* This is my no. 1 go-to serum. I have been using it since 2021 and have seen a great improvement in the smoothness of my skin, particularly around my eyes. One morning in 2021, I looked in the mirror and it was like somebody pulled a switch. The delicate skin around the eyes, that had been fairly smooth, suddenly sagged and looked baggy. None of my existing products did anything. Fortunately, I saw a TV commercial for the N1O1 serum and decided to give it a try. Since I am a woman of a certain age, I followed the instructions and began using it twice a day, with emphasis on the eye area. I have sensitive skin around the eyes and on the cheeks. There was, and still is, no irritation. Within about 3 days, there was improvement. The skin looked much more lifted. The whole eye area began to smooth out. In fact, since I was applying the serum over my whole face, my facial skin began to look smoother. Pores looked smaller, and the skin tone was more even. The effect of the serum seems to build over time. I continue to use the serum every day and am very pleased with the results. ### ⭐ One dispenser was inoperable *by J***W on March 3, 2023* I was very excited to use the serum as I have had great results with their eye cream. The unit is packaged as two separate products in one bottle. So there are two dispensers and the instructions state to dispense one pump from each dispenser and mix them both together to activate the serum. One dispenser worked fine, the other one didn't dispense anything. The pump worked, but nothing came out. Amazon was great about the return and I really wanted a replacement because I did want to try the serum but at just under $200 for a small bottle I didn't want to take a chance on this packaging defect being an issue again. ## Frequently Bought Together - Nitric Oxide Activating Serum with Antioxidants | Hydrating Serum For Face | Decreases Wrinkles | Pore Minimizer | Improves Skin Texture | Helps Dark Spots | 1 Fl Oz, 30ml - N1O1 Nitric Oxide Lozenges - 60 Count - Nitric Oxide Supplement for Heart Health, Circulation, Energy, Blood Flow, Oxygenation, Healthy Blood Pressure, Cardiovascular Support for Men & Women - N1O1 Moisturizer Face Cream - Day & Night Face Moisturizer with Nitric Oxide, Peptide Complex, Epidermal Growth Factor - Tightening & Firming Skin Care Products for Wrinkles, Dark Spots - 1.75 oz. --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/247862108-nitric-oxide-activating-serum-with-antioxidants-hydrating-serum-for-face](https://www.desertcart.us/products/247862108-nitric-oxide-activating-serum-with-antioxidants-hydrating-serum-for-face) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-05-18*