---
product_id: 202250885
title: "Nioxin Hair Thickening Serum | Night Density Rescue Serum | Density Defend Diamax Advanced | For Thicker, Fuller-Looking Hair | Against Breakage"
brand: "nioxin"
price: "$82.37"
currency: USD
in_stock: true
reviews_count: 13
category: "Nioxin"
url: https://www.desertcart.us/products/202250885-nioxin-hair-thickening-serum-night-density-rescue-serum-density-defend
store_origin: US
region: United States of America
---

# Overnight leave-on treatment Clinically proven density boost Antioxidant scalp protection Nioxin Hair Thickening Serum | Night Density Rescue Serum | Density Defend Diamax Advanced | For Thicker, Fuller-Looking Hair | Against Breakage

**Brand:** nioxin
**Price:** $82.37
**Availability:** ✅ In Stock

## Summary

> 🌟 Nightly rescue for hair that demands to be noticed

## Quick Answers

- **What is this?** Nioxin Hair Thickening Serum | Night Density Rescue Serum | Density Defend Diamax Advanced | For Thicker, Fuller-Looking Hair | Against Breakage by nioxin
- **How much does it cost?** $82.37 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/202250885-nioxin-hair-thickening-serum-night-density-rescue-serum-density-defend)

## Best For

- nioxin enthusiasts

## Why This Product

- Trusted nioxin brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted salon expertise:** From the only salon brand with 25+ years specializing in thinning hair, supported by trichologists.
- • **Wake up to thicker hair:** Overnight formula harnesses your body's natural regeneration cycle for visible density gains.
- • **Clinically backed confidence:** Proven to reduce hair fall linked to scalp oxidation in just 3 months.
- • **Powerful antioxidant defense:** Nioxydine(24) technology neutralizes free radicals to protect and revitalize your scalp.
- • **Lightweight, fast-drying serum:** Non-greasy, minty fresh feel that absorbs quickly without residue—perfect for nightly use.

## Overview

Nioxin Night Density Rescue Serum is a dermatologist-tested, overnight leave-on treatment designed to reduce hair fall caused by scalp surface oxidation. Featuring Nioxydine(24) antioxidant technology, it promotes thicker, fuller-looking hair within 3 months. Lightweight and fast-drying, this serum is trusted by professionals and backed by over 25 years of salon expertise in thinning hair care.

## Description

Product Description Dermatologically tested Nioxin Night Density Rescue Intensive Treatment effectively promotes hair density by reducing hair fall associated with scalp surface oxidation for thicker, fuller-looking hair. It is inspired by the nightly body’s regeneration process and contains Nioxydine(24) Technology, a powerful blend of antioxidants known to neutralize free radicals. A leave-on night treatment proven to promote hair density by reducing hair fall associated with scalp surface oxidation in 3 months* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Nioxin Nioxin is the only salon brand with 25+ years of experience in thinning hair. Nioxin, supported by The Institute of Trichologists, believes the scalp is an extension of facial skin and requires the same attention and care.

Review: This serum is liquid gold in a bottle! - I've noticed that my hair has been falling out in clumps in the shower pretty consistently for a while now. My hair used to be pretty thick, but I've noticed recently that my pony tail was looking a lot thinner than it used to, which was a little upsetting. 🫠 I've tried a few different hair loss/hair fall shampoos and serums over the year and I finally found one that works for me! I used this for a week and I feel like I noticed that the hair fall I had in the shower had reduced significantly! At first, I thought that maybe it was a coincidence, but even since I've started using this consistently every night, I haven't had another instance of increased hair fall in the shower. I've been using this every night (2-3 droppers full) all over my scalp. It works well on dry or damp hair, as it has alcohol in it, making it dry pretty dang quickly. It smells really nice, does not leave any sticky residue, and leaves a nice minty feeling on your scalp after you work it in there. I think my only problem with this is that, the instructions says to use 2-4 droppers each time. However, I find that if I keep doing that, I'll go through the bottle way too quickly and this stuff is NOT cheap. I may have to try using a little less each time, and hopefully it still works. Obviously, my personal experience is anecdotal, and depending on what the cause of your hair loss is, this product may not work for everyone. But for me, this stuff is like liquid gold in a bottle! This review isn't sponsored or anything (though, I'd definitely love it if it were 👀), just wanted to share my personal experience.
Review: yes - I'm not totally sure what type or specific category of voodoo magic this is, but I've been converted. consistency of water, and dries just as fast, if not quicker than water. does not leave a hint of grease or residue on hair, scalp, or pillow. scent is light but pleasant. bottle is bigger than i expected. directions say to apply 3-4 drops nightly, but i do about 7-10 tbh. it literally dries so quick and i cant feel it, so it sometimes leaves me like "did it even go on?" but it must, because i got actual real life results. within like 3 days my hair looked healthier. within a week i had about half the amount of hair falling out in the shower and during the day. after 2 weeks, one of my widening parts definitely looked fuller. the other widening part i haven't noticed a change though. after 3 weeks, my hair looks thicker and more full, with volume. you must be consistent with this and use it every single night. maybe twice i skipped 2 days in a row and the hair falling in the shower increased like immediately. once i started back up, it decreased again. so idk if that means i just need to use it for the rest of my life...? I'm 1 year post partum, but my hair falling, thinning, and widening parts is like 90% due to age, stress, and scalp flakes/dandruff/seb. dermatitis. 36 year old female.

## Features

- Overnight leave-on treatment, clinically proven to increase hair density associated with scalp surface oxidation
- High potential to neutralize free radicals, avoiding possible damages on the scalp

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B087KG95BK |
| Age Range (Description) | Adult |
| Age Range Description | Adult |
| Best Sellers Rank | #10,221 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #58 in Scalp Treatments |
| Brand | NIOXIN |
| Brand Name | NIOXIN |
| Customer Reviews | 4.3 out of 5 stars 1,286 Reviews |
| Hair Type | Thinning |
| Item Form | Serum |
| Item Volume | 62.4 Fluid Ounces |
| Item Weight | 2.4 Ounces |
| Manufacturer | Nioxin |
| Manufacturer Part Number | 070018102942 |
| Model Number | 070018102942 |
| Number of Items | 1 |
| Recommended Uses For Product | Professional Salon & Spa |
| Scent | Unscented |
| Scent Name | Unscented |
| Unit Count | 2.4 Ounce |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** NIOXIN
- **Item Form:** Serum
- **Item Weight:** 2.4 Ounces
- **Scent:** Unscented

## Images

![Nioxin Hair Thickening Serum | Night Density Rescue Serum | Density Defend Diamax Advanced | For Thicker, Fuller-Looking Hair | Against Breakage - Image 1](https://m.media-amazon.com/images/I/61iZ2g+M9wL.jpg)

## Available Options

This product comes in different **Style** options.

## Questions & Answers

**Q: Good for 85 year old woman?**
A: I would be happy to assist you with this question today. Our Nioxin Night Density Rescue is not age specific. This product assists with scalp and hair loss concerns. It is a leave-on night treatment that is proven to promote hair density by reducing hair fall associated with Scalp surface oxidation. This product is for anyone who has hair fall concerns. I hope this answered your question today. If you have more questions please feel free to contact and call our Licensed Stylists at 1-800-935-5273 to assist you with with any information you are looking for. Have a Beautiful Day!

**Q: What exactly is scalp surface oxidation?**
A: To answer your question about Nioxin Night Density Rescue concerning the scalp surface oxidation and what it is exactly the following will explain more.
Recent studies have shown that free radicals in the environment can trigger scalp oxidation and ultimately, hair thinning, Free radicals are unstable molecules that in an attempt to become more stable, steal electrons from other molecules which results in oxidative damage. This process is similar to the skin damage caused by the sun. To combat and minimize this damage in the world of skin care, there are a multitude of night time product regimens that both protect and repair skin. As night is the optimum time for the body to rest and repair itself, this is a prime opportunity to treat the hair and scalp as well. This is why we recommend our Nioxin Night Density Rescue to assist with repairing the scalp from damaged oxidative issues. I hope this was helpful to you. Have a Beautiful Day!

**Q: Does this have to be used forever or is this a temporary thing?**
A: This is a great question I am happy to assist you with. 

You can use our Nioxin Night Density Rescue as long or as short of a time as you wish. If you get the results you are looking for you can stop without fear of hair fall or you can continue to use it for preventative scalp care.

I hope this answered your question today.
Have a Wonderful Nioixin Hair Day!

**Q: Can I used this product and the nioxin 4 scalp & hair treatment? I mean this one at night and the other when I wash my hair with the system at morning**
A: This is a perfect question I would be happy to answer for your today. Yes, you can use this at night and also use the Scalp and Hair Treatment when you use all 3 System products during the day. This is exactly how this product should be used and you will see great results while using these products as discussed. 
Use your System Kit Cleansing Shampoo, Scalp Therapy Conditioner and Scalp and Hair Treatment when you shampoo use all 3 products. 
At night Use our NIoxin 3D Intensive Therapy Night Density Rescue. Dermatologically tested Nioxin Night Density Rescue Intensive Treatment effectively promotes hair density by reducing hair fall associated with scalp surface oxidation for thicker, fuller-looking hair. It is inspired by the nightly body’s regeneration process and contains Nioxydine(24) Technology, a powerful blend of antioxidants known to neutralize free radicals. A leave-on night treatment proven to promote hair density by reducing hair fall associated with scalp surface oxidation in 3 months.
I hope you find the results you are looking for using our products. You are using the products we recommend most to our clients.
I hope this answered your question today.
Have a Wonderful Day!

## Customer Reviews

### ⭐⭐⭐⭐⭐ This serum is liquid gold in a bottle!
*by K***W on December 15, 2025*

I've noticed that my hair has been falling out in clumps in the shower pretty consistently for a while now. My hair used to be pretty thick, but I've noticed recently that my pony tail was looking a lot thinner than it used to, which was a little upsetting. 🫠 I've tried a few different hair loss/hair fall shampoos and serums over the year and I finally found one that works for me! I used this for a week and I feel like I noticed that the hair fall I had in the shower had reduced significantly! At first, I thought that maybe it was a coincidence, but even since I've started using this consistently every night, I haven't had another instance of increased hair fall in the shower. I've been using this every night (2-3 droppers full) all over my scalp. It works well on dry or damp hair, as it has alcohol in it, making it dry pretty dang quickly. It smells really nice, does not leave any sticky residue, and leaves a nice minty feeling on your scalp after you work it in there. I think my only problem with this is that, the instructions says to use 2-4 droppers each time. However, I find that if I keep doing that, I'll go through the bottle way too quickly and this stuff is NOT cheap. I may have to try using a little less each time, and hopefully it still works. Obviously, my personal experience is anecdotal, and depending on what the cause of your hair loss is, this product may not work for everyone. But for me, this stuff is like liquid gold in a bottle! This review isn't sponsored or anything (though, I'd definitely love it if it were 👀), just wanted to share my personal experience.

### ⭐⭐⭐⭐⭐ yes
*by D***B on October 13, 2025*

I'm not totally sure what type or specific category of voodoo magic this is, but I've been converted. consistency of water, and dries just as fast, if not quicker than water. does not leave a hint of grease or residue on hair, scalp, or pillow. scent is light but pleasant. bottle is bigger than i expected. directions say to apply 3-4 drops nightly, but i do about 7-10 tbh. it literally dries so quick and i cant feel it, so it sometimes leaves me like "did it even go on?" but it must, because i got actual real life results. within like 3 days my hair looked healthier. within a week i had about half the amount of hair falling out in the shower and during the day. after 2 weeks, one of my widening parts definitely looked fuller. the other widening part i haven't noticed a change though. after 3 weeks, my hair looks thicker and more full, with volume. you must be consistent with this and use it every single night. maybe twice i skipped 2 days in a row and the hair falling in the shower increased like immediately. once i started back up, it decreased again. so idk if that means i just need to use it for the rest of my life...? I'm 1 year post partum, but my hair falling, thinning, and widening parts is like 90% due to age, stress, and scalp flakes/dandruff/seb. dermatitis. 36 year old female.

### ⭐⭐⭐⭐⭐ Works after GLP-1 Drug Hair Thinning, stress hair thinning - THUMBS UP
*by R***Y on September 11, 2025*

After changing medications, including addition of Ozempic (GLP-1) into my medication list, within 3 months my hair started to thin more then normal. My hair is long and waist length, normal shed is about 100 hairs a day, but this had increased. I increased protein intake which did help. I have always taken MSM (Methylsulfonylmethane) supplements which have given me very thick hair, and have continued them ( 2000 mg daily) I have been taking Minoxidil generic 5%, for about 5 years already ( to combat post menopause hair thinning) which continued to help. But due to a drug reaction, (not the glp, another rx) I became severely sick, could not eat or drink much for two weeks, ended up the the hospital for a week, had a platelet transfusion. I was very sick. I am ok now, but after leaving the hospital I began losing baseball sized wads of shed hair daily. My hair had dramatically thinned. From a medium ponytail to a pencil sized tail. Probably have lost 3/4 of my hair thickness. Then I started this product, within 3 weeks less hair was dropping, and after about 4 -6 weeks, hair thinning is down to less then 50 strands a day. Dramatic difference when I brush hair. I still need to regrow lost hair, which usually takes about 6 weeks to get going, and it i will be awhile for it ta catch up enough to be noticed in my length and fullness. But less shed is amazing. I apply daily, many drops all over entire scalp (not just three like listing says) - Fully recommend this! Update added. Its been 4-5 months since orginal review. Still using, and recommending this product. I now loose maybe 10 to 12 hairs aday in normal shedding. My hair is super super thick, and length is growing as well. Still taking Ozempic, but you would never know from my hair thickness. At age 61, it's the fullest it has ever been. Much fuller then in my youth. Still using minoxidil, and MSM supplements. Highly recommend this product.

## Frequently Bought Together

- Nioxin Night Density Rescue Serum | Overnight Hair Thickening Serum | Protects Against Hair Breakage | Intensive Treatment with Oxydine | 2.4 Fl oz.
- Nioxin Density Defend Styling Root Lifting Spray | Hair Thickening Spray | Texturizes and Volumizes | 5.1 Fl oz.
- Nioxin Density Defend Hair Thickening Gel | For Volumizing and Fuller Hair| No Stickiness or Stiffness | 5.1 Fl Oz

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-07-09*