---
product_id: 180275428
title: "Signature Allergy Medicine Diphenhydramine 25 Mg 600 Count (Pack of 2)"
brand: "kirkland"
price: "$48.42"
currency: USD
in_stock: true
reviews_count: 13
category: "Kirkland"
url: https://www.desertcart.us/products/180275428-signature-allergy-medicine-diphenhydramine-25-mg-600-count-pack-2
store_origin: US
region: United States of America
---

# fast-acting relief 25mg potent dose 1200 pills total Signature Allergy Medicine Diphenhydramine 25 Mg 600 Count (Pack of 2)

**Brand:** kirkland
**Price:** $48.42
**Availability:** ✅ In Stock

## Summary

> 💥 Stay ahead of allergies and sleep tight with Kirkland’s powerhouse pack!

## Quick Answers

- **What is this?** Signature Allergy Medicine Diphenhydramine 25 Mg 600 Count (Pack of 2) by kirkland
- **How much does it cost?** $48.42 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/180275428-signature-allergy-medicine-diphenhydramine-25-mg-600-count-pack-2)

## Best For

- kirkland enthusiasts

## Why This Product

- Trusted kirkland brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Dual Purpose Use:** Effective for allergy relief and natural sleep support—your nighttime ally
- • **Powerful 25mg Dose:** Clinically proven antihistamine strength for effective allergy relief
- • **Rapid Symptom Relief:** Fast-acting formula to keep you ahead of sneezes and sniffles
- • **Bulk Pack Convenience:** Two bottles totaling 1200 pills—never run out during allergy season
- • **Trusted Kirkland Quality:** Reliable brand with 4.8-star rating from over 1,600 users

## Overview

Kirkland Signature Diphenhydramine HCL 25mg offers a high-potency antihistamine solution in a value-packed set of two bottles, totaling 1200 tablets. Trusted by thousands with a 4.8-star rating, this fast-acting allergy medicine doubles as a natural sleep aid, making it an essential staple for managing seasonal allergies and improving rest.

## Description

Kirkland Diphenhydramine HCL 25mg Allergy Medicine and Antihistamine - 2 bottles of 600ct for a total of 1200pills

Review: Great product. great price. - What is not to like. Three of these before bed and I am in Lala Land in about two hours. It takes my wife one hour to work. Our bodies produce this stuff so it is about as natural as one can get. Been using it for sleep for years. Zero complaints.
Review: Great value - Great value

## Features

- Diphenhydramine HCI 25 Mg - Kirkland Brand - Allergy Medicine and Antihistamine - 600 count, 2 pack

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B07Y3R5ZNJ |
| Best Sellers Rank | #80,266 in Health & Household ( See Top 100 in Health & Household ) #311 in Allergy Medicine |
| Customer Reviews | 4.8 4.8 out of 5 stars (1,603) |
| Date First Available  | September 19, 2019 |
| Item model number  | 536099 |
| Manufacturer  | Kirkland Signature |
| Product Dimensions  | 10 x 3 x 13 inches; 6.4 ounces |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** KIRKLAND
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Item Weight:** 6.4 ounces
- **Item dimensions L x W x H:** 10 x 3 x 13 inches
- **Number of Items:** 2
- **Package Information:** Bottle
- **Primary Supplement Type:** Diphenhydramine
- **Unit Count:** 1200 Count

## Images

![Signature Allergy Medicine Diphenhydramine 25 Mg 600 Count (Pack of 2) - Image 1](https://m.media-amazon.com/images/I/71HdddNn1CL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: I discovered that this has "talc" as an inactive ingredient... Can anyone confirm or disprove?**
A: In the ingredients there is nothing like talc. At least I don't see it and I have long time taking that brand without any health problem

**Q: Any other ingredients in these besides Diphenhydramine?**
A: It says: Other information calcium 30 mg
Inactive ingredients; corn starch, D&C red #27, aluminium lake, dicalcium phosphate, magnesium stearate,microcrystalline cellulose,polyethelene glycol, polyvinyl alcohol, silicon dioxide, stearic acid and titanium dioxide.

No other active ingredients, just the diphenhydramine HCI 25mg.

**Q: Is this a legitimate costco product?  i don't see this product on costco's web site.  who is he seller kah-mart.  makes me think this is a rip off.**
A: I know of no reason to think this product is illegitimate or a ripoff.  This generic Benadryl/Dyphenhydramine is widely available from many different sellers and manufacturers.  Why do you think it's fake?  Simply because you could not find it on the Costco website is meaningless.  Does the product work as Benadryl or its generic equivalent should.  For me, yes.  It is a classic antihistamine that eases an itchy skin rash for me.  Also, it aids sleep.  This 600-quantity bottle is a great bargain.

**Q: en que tiempo caducan?**
A: La fecha de caducidad de un medicamento no es el mismo todo depende del día y mes en que se fabricó. Ejemplo: si el usted compró se manofacturo o se fabricó en enero y le dan tres meses para vencerse y, el que yo compre se produjo en Abril no van a caducar en igual fecha

## Customer Reviews

### ⭐⭐⭐⭐⭐ Great product. great price.
*by A***R on February 5, 2026*

What is not to like. Three of these before bed and I am in Lala Land in about two hours. It takes my wife one hour to work. Our bodies produce this stuff so it is about as natural as one can get. Been using it for sleep for years. Zero complaints.

### ⭐⭐⭐⭐⭐ Great value
*by H***K on December 6, 2025*

Great value

### ⭐⭐⭐⭐⭐ Gives a good night sleep
*by F***. on December 3, 2025*

Easy to take and it works. It put me asleep in 30 minutes. I awoke bright and sharp.

## Frequently Bought Together

- Kirkland Signature Allergy Medicine Diphenhydramine 25 Mg 600 Count (Pack of 2)
- Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)
- HealthA2Z Sleep Aid, Diphenhydramine Softgels, 50mg, Supports Deeper, Restful Sleeping (250 Counts)

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**Shop now:** [https://www.desertcart.us/products/180275428-signature-allergy-medicine-diphenhydramine-25-mg-600-count-pack-2](https://www.desertcart.us/products/180275428-signature-allergy-medicine-diphenhydramine-25-mg-600-count-pack-2)

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-02-12*