---
product_id: 168054213
title: "Host Defense Lion's Mane Powder, Brain Health, 3.5 oz | Brain Health Supplement, Mushroom Supplement to Support Mental Clarity, Focus, and Memory Function, 66 Servings"
brand: "host defense"
price: "$58.79"
currency: USD
in_stock: true
reviews_count: 9
category: "Host Defense"
url: https://www.desertcart.us/products/168054213-host-defense-lions-mane-powder-brain-health-3-5-oz
store_origin: US
region: United States of America
---

# Certified organic, non-GMO, vegan 66 servings of brain-boosting power Grown sustainably in the USA Host Defense Lion's Mane Powder, Brain Health, 3.5 oz | Brain Health Supplement, Mushroom Supplement to Support Mental Clarity, Focus, and Memory Function, 66 Servings

**Brand:** host defense
**Price:** $58.79
**Availability:** ✅ In Stock

## Summary

> 🧠 Elevate your mind, own your day — the smart mushroom revolution starts here!

## Quick Answers

- **What is this?** Host Defense Lion's Mane Powder, Brain Health, 3.5 oz | Brain Health Supplement, Mushroom Supplement to Support Mental Clarity, Focus, and Memory Function, 66 Servings by host defense
- **How much does it cost?** $58.79 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/168054213-host-defense-lions-mane-powder-brain-health-3-5-oz)

## Best For

- host defense enthusiasts

## Why This Product

- Trusted host defense brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Pure Organic Power:** Certified organic, gluten-free, and non-GMO for clean, guilt-free brain support
- • **Unlock Laser-Sharp Focus:** Clinically supported Lion's Mane mycelium fuels mental clarity and memory retention*
- • **Daily Dose of Cognitive Edge:** Convenient powder form with 66 servings per jar—perfect for your morning ritual
- • **Sustainably Grown in the USA:** Ethically cultivated on organic brown rice substrate for premium potency
- • **Trusted by Experts & Enthusiasts:** Formulated by mycology pioneer Paul Stamets, backed by thousands of 5-star reviews

## Overview

Host Defense Lion's Mane Powder is a 3.5 oz organic mushroom mycelium supplement designed to support brain health, focus, and memory. With 66 servings per jar, it is vegan, non-GMO, gluten-free, and sustainably grown in the USA on organic brown rice substrate. Developed by renowned mycologist Paul Stamets, this powder offers a clean, daily cognitive boost trusted by thousands.

## Description

desertcart.com : Host Defense Lion's Mane Powder, Brain Health, 3.5 oz | Brain Health Supplement, Mushroom Supplement to Support Mental Clarity, Focus, and Memory Function, 66 Servings : Health & Household

Review: Great product, works for me! - I have used this Lion's Mane powder for over a year. There is a noticable difference in memory function when I don't take it for awhile. Will continue to purchase.
Review: High quality organic product - Excellant quality product, very different texture from the fruiting bodies type which I also use. Still waiting for the full positive affects of the mycellium but I can tell by the quality it won't be much longer. I mix it along with the fruiting body mushroom powder in my chaga mushroom coffee every morning.

## Features

- Lion's Mane for Brain Support: This mushroom supplement supports immune and nervous system health as well as brain health, making it an ideal dietary supplement for those wanting to aid their focus and memory*
- Dietary Supplement with Mushroom Mycelium: Our brain and focus support supplement is formulated with Lion's Mane, "The Smart Mushroom," for daily brain support*
- About Host Defense: Host Defense Mushrooms was founded by renowned mycologist Paul Stamets; our mushroom mycelium is certified organic, non-GMO, gluten-free, and grown in the USA*
- Powered by Mushroom Mycelium: Our organic mushroom mycelium is grown on organic brown rice substrate; third-party studies show that mushroom mycelium and fermented rice substrate support your health*
- Lion's Mane Dietary Supplement: As a dietary supplement, take a 1/2 teaspoon 1–3 times daily with food or on an empty stomach, or as recommended by your healthcare advisor

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07TJ63MH3 |
| Age Range Description | Adult |
| Best Sellers Rank | #19,441 in Health & Household ( See Top 100 in Health & Household ) #86 in Mushrooms Herbal Supplements |
| Brand | Host Defense |
| Brand Name | Host Defense |
| Container Type | Jar |
| Customer Reviews | 4.6 out of 5 stars 3,272 Reviews |
| Diet Type | Vegan |
| Dosage Form | Powder |
| Flavor | Organic |
| Item Form | Powder |
| Item Package Quantity | 1 |
| Item Weight | 4.8 ounces |
| Manufacturer | Host Defense |
| Manufacturer Part Number | NPHE100G |
| Material Features | Organic |
| Model Number | NPHE100G |
| Number of Items | 1 |
| Package Information | Jar |
| Package Quantity | 1 |
| Recommended Uses For Product | Brain Health |
| UPC | 633422306964 |
| Unit Count | 3.5 Ounce |

## Product Details

- **Brand:** Host Defense
- **Item Form:** Powder
- **Item Package Quantity:** 1
- **Manufacturer:** Host Defense
- **Package Information:** Jar

## Images

![Host Defense Lion's Mane Powder, Brain Health, 3.5 oz | Brain Health Supplement, Mushroom Supplement to Support Mental Clarity, Focus, and Memory Function, 66 Servings - Image 1](https://m.media-amazon.com/images/I/81gXuaYw8oL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Do the mycelium have the same compounds in them as the fruiting bodies?  All the information I have seen/heard has focused on the mushrooms not roots.**
A: Host Defense has done a massive amount of research to make these supplements as potent and effective as possible. They have found that the mycelium is the most effective at helping with the conditions addressed with each product. Some products do contain fruit body as well. Host Defense uses mycelium because the mycelium contains the higher concentration of the nutrition of the mushroom, and also produces compounds that are not found in fruiting bodies. You can read more about the Benefits of Mycelium here: https://hostdefense.com/blogs/host-defense-blog/immune-benefits-of-mushroom-mycelium-cultured-substrate-confirmed

**Q: Does it carry carry the united states pharmacopeia (usp) or nsf international (nsf) seal?**
A: Not anywhere on the container that I can see.

**Q: How is the myecelium separated from the substrate it grows on? Or is this product mostly substrate?**
A: no separated, probably most of it would be rice bran substrate as carbs.

**Q: Is this sold directly by host defense? i do not want to end up with a fake copy of this product -- i want the real deal.**
A: "Orders from Netrush are guaranteed to be authentic. We are Host Defense's authorized Amazon retailer. This can be confirmed by contacting them directly: https://hostdefense.com/pages/contact-us

## Customer Reviews

### ⭐⭐⭐⭐⭐ Great product, works for me!
*by K***L on April 19, 2026*

I have used this Lion's Mane powder for over a year. There is a noticable difference in memory function when I don't take it for awhile. Will continue to purchase.

### ⭐⭐⭐⭐⭐ High quality organic product
*by M***S on July 16, 2026*

Excellant quality product, very different texture from the fruiting bodies type which I also use. Still waiting for the full positive affects of the mycellium but I can tell by the quality it won't be much longer. I mix it along with the fruiting body mushroom powder in my chaga mushroom coffee every morning.

### ⭐⭐⭐⭐⭐ Quality Lion's Mane
*by B***E on August 30, 2020*

If you are unfamiliar with Paul Stamets you should look more into him and his products. He is a leader in mycology and really cares about the help he can provide with quality products and information. Results: I do feel as if Lion's Mane has added some more clarity to my daily brain function. I have been using it for a month now. I don't quite know how to describe it as this isn't a miracle drug but I can just say I have less foggy days have a better well being day to day. I have noticed it is easier to focus and learn things through my new job and grad school. There is lots of good medical research to back up these claims. Consumption method: The quality seems great as it is grated well and consistently. Next time I may get the pills though, but the price per does it much better in this product. I first tried taking it straight and washing it down with a gulp of water because I thought I would have no problem. However, it didn't go quite as planned. I started putting it in my coffee everyday but I am a stickler of the residue of little bits that stay behind. I went back to taking it straight and it really isn't that bad now. The taste is almost like a woody undertones but besides that it is more of a texture thing with how it mixes if you are trying to take it straight. If you are able to mix it in a drink there is no taste to me and the texture is minimal, think medium pulp orange juice.

## Frequently Bought Together

- Host Defense Lion's Mane Powder - Brain Health Support Supplement - Mushroom Supplement to Support Focus & Memory Function - Immune & Nervous System Support Supplement - 3.5 oz (66 Servings)*
- Host Defense Turkey Tail Mushroom Powder - Digestive Health & Immune Response Support Supplement - Mushroom Supplement for Gastrointestinal & Gut Microbiome Support - 3.5 oz (66 Servings)*
- Host Defense Reishi Powder - Mushroom Mycelium Powder - Heart & Immune Health Support Supplement - Mushroom Supplement to Support Energy & Vitality - Aids Overall Well-Being - 3.5 oz (66 Servings)*

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-08-15*