---
product_id: 15546741
title: "Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets"
brand: "prilosec"
price: "$53.49"
currency: USD
in_stock: true
reviews_count: 8
url: https://www.desertcart.us/products/15546741-prilosec-otc-omeprazole-delayed-release-20mg-acid-reducer-treats-frequent
store_origin: US
region: United States of America
---

# 24-hour acid control 20mg delayed-release Omeprazole Effective from Day 1 Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets

**Brand:** prilosec
**Price:** $53.49
**Availability:** ✅ In Stock

## Summary

> 🔥 Beat heartburn all day and night — because your hustle never stops!

## Quick Answers

- **What is this?** Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets by prilosec
- **How much does it cost?** $53.49 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/15546741-prilosec-otc-omeprazole-delayed-release-20mg-acid-reducer-treats-frequent)

## Best For

- prilosec enthusiasts

## Why This Product

- Trusted prilosec brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Fast-Acting from Day One:** Starts working immediately to keep discomfort at bay.
- • **FSA/HSA Eligible & Convenient:** 42 tablets in a compact blister pack, perfect for busy professionals.
- • **Clinically Proven Acid Reducer:** 20mg delayed-release Omeprazole targets excess acid production at the source.
- • **Trusted by Doctors for 15 Years:** The #1 recommended frequent heartburn medicine, backed by gastroenterologists.
- • **All-Day, All-Night Heartburn Blocker:** One morning pill delivers 24-hour relief so you never miss a beat.

## Overview

Prilosec OTC delivers powerful, 24-hour relief from frequent heartburn with a single 20mg delayed-release Omeprazole pill each morning. Clinically proven and doctor-recommended for over 15 years, it prevents excess stomach acid production starting from day one. Ideal for adults experiencing heartburn 2+ times weekly, this blister-packaged treatment is FSA/HSA eligible and designed for consistent, long-lasting comfort.

## Description

With one Prilosec OTC pill in the morning, block your heartburn all day and all night.* Heartburn happens when stomach acid refluxes into the esophagus. Prilosec OTC’s delayed-release formula helps it pass through the tough stomach acid, preventing excess acid production to block frequent heartburn.* Some other heartburn relief treatments only neutralize the stomach acid after it’s already been produced and provide shorter relief (less than 24 hours). Prilosec OTC is the #1 Doctor and Gastroenterologist recommended frequent heartburn medicine for 15 straight years.^ * It’s possible while taking Prilosec OTC. Proton Pump Inhibitors like Prilosec OTC work differently to treat frequent heartburn for 14 days. Compared to how antacids and H2 blockers work for heartburn. Use all heartburn medications as directed. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. Not for immediate relief. ^IQVIA ProVoice Survey, Jan 2005 – Mar 2020.

Review: No more heartburn!! - Works wonders!!!!
Review: daily use with confidence - this is a great product, and it really works / I take it every day with 100% effective results

## Features

- TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week
- With 1 PRILOSEC OTC PILL in the morning, BLOCK HEARTBURN. ALL DAY. ALL NIGHT.*
- PREVENT EXCESS ACID PRODUCTION for heartburn relief that lasts for 24 HOURS.* Starts working on DAY 1*
- CONTAINS ACTIVE INGREDIENT OMEPRAZOLE delayed-release 20mg, an acid reducer that provides long-lasting, heartburn relief*
- FSA and HSA eligible

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0014E1FP0 |
| Active Ingredients | Omeprazole |
| Age Range Description | Adult |
| Best Sellers Rank | #75,964 in Health & Household ( See Top 100 in Health & Household ) #269 in Antacids |
| Brand | Prilosec |
| Brand Name | Prilosec |
| Container Type | Box |
| Customer Reviews | 4.8 out of 5 stars 1,189 Reviews |
| Dosage Form | Tablets |
| Global Trade Identification Number | 00037000359074 |
| Included Components | 80348738 |
| Item Dimensions | 5 x 3.8 x 2.4 inches |
| Item Form | Tablet |
| Item Nype Name | antacids |
| Item Weight | 2.4 ounces |
| Item dimensions L x W x H | 5 x 3.8 x 2.4 inches |
| Manufacturer | Prilosec OTC |
| Manufacturer Part Number | thomaswi |
| Model Name | Prilosec Otc Relief Tablets |
| Model Number | 80348738 |
| Net Content Count | 42 Count |
| Number of Items | 1 |
| Package Type Name | Blister |
| Product Benefits | Acidity Relief |
| Specific Uses For Product | Heartburn |
| Target Audience | Unisex-Adults |
| Target Use Body Part | Stomach |
| UPC | 037000359074 |
| Unit Count | 42 Count |

## Product Details

- **Brand:** Prilosec
- **Item Weight:** 2.4 ounces
- **Item dimensions L x W x H:** 5 x 3.8 x 2.4 inches
- **Product Benefits:** Acidity Relief
- **Specific Uses For Product:** Heartburn

## Images

![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 1](https://m.media-amazon.com/images/I/71ZXW2Ft1OL.jpg)
![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 2](https://m.media-amazon.com/images/I/81QriE9rkxL.jpg)
![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 3](https://m.media-amazon.com/images/I/71SFHTFSAiL.jpg)
![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 4](https://m.media-amazon.com/images/I/61fYt1Hl29L.jpg)
![Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets - Image 5](https://m.media-amazon.com/images/I/71DhQ+XqXBL.jpg)

## Available Options

This product comes in different **Size** options.

## Customer Reviews

### ⭐⭐⭐⭐⭐ No more heartburn!!
*by N***Y on February 22, 2026*

Works wonders!!!!

### ⭐⭐⭐⭐⭐ daily use with confidence
*by C***Z on April 30, 2026*

this is a great product, and it really works / I take it every day with 100% effective results

### ⭐⭐⭐⭐⭐ It works
*by D***E on April 19, 2026*

It really works

## Frequently Bought Together

- Prilosec OTC Frequent Heartburn Relief Medicine and Acid Reducer 42 Tablets Omeprazole Delayed-Release Tablets 20mg - Proton Pump Inhibitor (OLD)
- Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 42 Tablets

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-05-18*