---
product_id: 129684032
title: "Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems"
brand: "zep"
price: "$84.25"
currency: USD
in_stock: true
reviews_count: 9
category: "Zep"
url: https://www.desertcart.us/products/129684032-zep-drain-defense-enzymatic-cleaner-powder-18-oz-case-2
store_origin: US
region: United States of America
---

# Safe for pipes & septic Enzyme-powered clog buster Biodegradable & eco-safe Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems

**Brand:** zep
**Price:** $84.25
**Availability:** ✅ In Stock

## Summary

> 🧼 Clear drains, clear mind — join the clean pipe revolution!

## Quick Answers

- **What is this?** Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems by zep
- **How much does it cost?** $84.25 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/129684032-zep-drain-defense-enzymatic-cleaner-powder-18-oz-case-2)

## Best For

- zep enthusiasts

## Why This Product

- Trusted zep brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Eco-Friendly Formula:** Certified biodegradable, breaking down into CO2, minerals, and water—safe for your home and planet.
- • **Enzyme-Driven Deep Clean:** Harnesses natural enzymes to break down stubborn gunk without harsh chemicals.
- • **Pipe & Septic System Safe:** Gentle on PVC and most septic systems, ensuring long-term plumbing health.
- • **Monthly Maintenance Made Easy:** Convenient powder form with scoops for hassle-free monthly use to prevent future clogs.
- • **Odor Control & Drain Freshness:** Effectively reduces basement and floor drain odors, keeping your home smelling clean and fresh.

## Overview

Zep Drain Defense Enzymatic Cleaner Powder is a powerful, enzyme-based solution designed to prevent and break down clogs in sinks, toilets, and showers. Its certified biodegradable formula safely dissolves organic buildup into harmless CO2, minerals, and water, making it safe for PVC pipes and septic systems. Packaged in convenient 18 oz scoops (case of 2), it’s ideal for monthly maintenance to keep your drains flowing smoothly and odor-free.

## Description

Zep is more than just another cleaning company. We are a passionate group who have been perfecting cleaning formulas for homes, businesses, and automobiles for over 85 years with one goal in mind: Making safe and efficacious products that do the job right the first time. Our products give you the efficacy of a deep clean without all the extra work. Featured Products Visit the Store Featured Products Visit the Store Shop Floor Care Visit the Store Shop Floor Care Shop Air Care Visit the Store Shop Air Care Shop Drain & Septic Visit the Store Shop Drain & Septic Shop Hand Care Visit the Store Shop Hand Care Zep products are all formulated in the U.S. with a dedicated R&D team who knows how to clean everything, from a small stain on a carpet to some of the toughest messes on Earth. And, because we have a professional heritage, our products surpass all standards for safety. At Zep, we care about cleaning because that is all we do. Upgrade your clean and experience the Zep difference! Zep products are all formulated in the U.S. with a dedicated R&D team who knows how to clean everything, from a small stain on a carpet to some of the toughest messes on Earth. And, because we have a professional heritage, our products surpass all standards for safety. At Zep, we care about cleaning because that is all we do. Upgrade your clean and experience the Zep difference!

## Features

- Helps prevent clogs in sinks, toilets and showers
- ENZYME BASED FORMULA: Breaks down drain-clogging elements. Use monthly to prevent future clogs from happening
- SAFE FOR: PVC and most other septic systems
- Certified, biodegradable formula, breaks down into carbon dioxide, minerals and water
- BREAKS DOWN: Into CO2, minerals and water

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07M5C4XK3 |
| Best Sellers Rank | #12,435 in Health & Household ( See Top 100 in Health & Household ) #222 in Chemical Drain Openers |
| Brand | Zep |
| Brand Name | Zep |
| Customer Reviews | 4.3 out of 5 stars 1,959 Reviews |
| Global Trade Identification Number | 20021709500169 |
| Item Weight | 18 Ounces |
| Liquid Volume | 532 Milliliters |
| Manufacturer | Zep |
| Number of Items | 2 |
| Part Number | ECZDC162 |
| Product Benefits | Helps prevent clogs in sinks, toilets and showers |
| Scent | Unscented |
| State of Matter | Solid |
| State of matter | Solid |
| Unit Count | 2.00 Count |

## Product Details

- **Brand:** Zep
- **Item Weight:** 18 Ounces
- **Product Benefits:** Helps prevent clogs in sinks, toilets and showers
- **Scent:** Unscented
- **State of matter:** Solid

## Images

![Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems - Image 1](https://m.media-amazon.com/images/I/516JHOSD+-L.jpg)
![Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems - Image 2](https://m.media-amazon.com/images/I/61tb8XvcciL.jpg)
![Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems - Image 3](https://m.media-amazon.com/images/I/51tBtwq6O6L.jpg)
![Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems - Image 4](https://m.media-amazon.com/images/I/619IqhqXFJL.jpg)
![Zep Drain Defense Enzymatic Cleaner Powder - 18 oz (Case of 2) ZDC16 - Safe for Pipes and Septic Systems - Image 5](https://m.media-amazon.com/images/I/61Fr0bjrOoL.jpg)

## Available Options

This product comes in different **Item Package Quantity** options.

## Questions & Answers

**Q: Which one is better or cheaper ? this one or the one which also made by zep but comes in 64 oz bottle  liquid form?**
A: The performance is one and the same. The Liquid Drain Defense Build-up Remover is available in 64 ounces and does not require mixing. Pour 1 ounce of the Liquid Drain Defense Build-up Remover into the drain, followed by 16 ounces of warm water. Whereas, the Drain Defense powder require to be premixed. Add one scoop of the powder into 16 ounces of warm water and pour the mixture into drain.

**Q: Does this dissolve toilet paper?**
A: Over time

**Q: Is this like the old drain care?  I want to use it in the bathroom for the stench out of the overfill drain.**
A: It seems to help with odor but not knowing what is causing your odor problem or how severe it is, I hesitate to say this product would be 100% effective on solving that problem. And I have no idea what “old drain care” is so I really don’t know.

**Q: Is this product safe for pex tubing?  I need to prevent fat buildup in my kitchen plumbing.**
A: Absolutely. When used as directed, Zep Drain Defense Pipe Build-up Remover is suitable for all plumbing, including "pex tubing." Use Zep Drain Defense Pipe Build-up Remover to dissolve years of grease, oil, and other drain clogging build-up.  For best results, mix 1 scoop of Zep Drain Defense Pipe Build-up Powder with 16 ounces of "warm" water and stir until treatment is properly mixed. Pour mixture into drain and allow treatment to work for 6 hours or overnight.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by F***K on April 15, 2026*



### ⭐⭐⭐⭐⭐ Review
*by V***A on April 11, 2026*



### ⭐⭐⭐⭐ Review
*by B***P on February 22, 2026*



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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-05-11*