--- product_id: 129475025 title: "Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 8" brand: "frontline" price: "$171.33" currency: USD in_stock: true reviews_count: 9 category: "Frontline" url: https://www.desertcart.us/products/129475025-plus-flea-and-tick-spot-treatment-for-x-large-breed store_origin: US region: United States of America --- # 30-day continuous protection Waterproof formula Kills fleas, eggs, larvae & ticks Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 8 **Brand:** frontline **Price:** $171.33 **Availability:** ✅ In Stock ## Summary > 🛡️ Stay ahead of pests — because your XL dog deserves frontline protection! ## Quick Answers - **What is this?** Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 8 by frontline - **How much does it cost?** $171.33 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/129475025-plus-flea-and-tick-spot-treatment-for-x-large-breed) ## Best For - frontline enthusiasts ## Why This Product - Trusted frontline brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **XL Dog Friendly:** Formulated specifically for dogs 89-132 lbs, ensuring safe and effective coverage. - • **Month-Long Defense:** One easy monthly dose shields your XL dog from fleas & ticks for a full 30 days. - • **Waterproof & Resilient:** Active ingredients deposit in skin glands, working even after baths or rain. - • **Trusted for Over 20 Years:** Veteran pet owners rely on FRONTLINE Plus for proven, consistent protection. - • **Complete Flea Lifecycle Control:** Kills adult fleas, eggs, larvae, and chewing lice to break infestations fast. ## Overview FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs delivers fast-acting, waterproof, and month-long protection against fleas, flea eggs, larvae, chewing lice, and ticks that transmit Lyme disease. Trusted by pet owners for over 20 years, its dual active ingredients (fipronil and (S)-methoprene) break the flea life cycle while continuously replenishing through the skin’s sebaceous glands. Designed for dogs weighing 89 to 132 lbs, this easy-to-apply topical treatment ensures your XL dog stays pest-free and comfortable all month long. ## Description Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention. Review: This stuff still works great - I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on desertcart! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more! Review: Still works in my part of the state - Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away... ## Features - Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease - Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control - Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days - FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products - Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations - Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B07NGXYVZZ | | ASIN | B07NGXYVZZ | | Active Ingredients | fipronil and (S)-methoprene | | Age Range Description | All Life Stages | | Allergen Information | Gluten Free | | Best Sellers Rank | #646 in Pet Supplies ( See Top 100 in Pet Supplies ) #8 in Dog Flea Drops | | Brand Name | Frontline | | Customer Reviews | 4.4 4.4 out of 5 stars (15,187) | | Date First Available | February 7, 2019 | | Dog Breed Size | Giant | | Included Components | Applicator | | Item Form | Liquid | | Item Type Name | Topical Red box | | Item Weight | 0.14 Pounds | | Item model number | 72220 | | Manufacturer | Boehringer Ingelheim Animal Health | | Manufacturer | Boehringer Ingelheim Animal Health | | Manufacturer Part Number | 72220 | | Manufacturer recommended age | 1 month and up | | Model Number | 72220 | | Product Dimensions | 1 x 5.75 x 4.5 inches; 2.24 ounces | | Scent Name | Unscented | | Target Species | Dog | | UPC | 611030624793 350604062479 | | Unit Count | 8 Count | | Volume | 32 Milliliters | | Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. | ## Product Details - **Active Ingredients:** fipronil and (S)-methoprene - **Age Range (Description):** All Life Stages - **Allergen Information:** Gluten Free - **Brand:** Frontline - **Dog Breed Size:** Giant - **Item Form:** Liquid - **Item Volume:** 32 Milliliters - **Item Weight:** 0.14 Pounds - **Scent:** Unscented - **UPC:** 611030624793 350604062479 ## Images ![Plus Flea & Tick Spot Treatment for X-Large Breed Dogs 89-132 lbs. (Red) Count of 8 - Image 1](https://m.media-amazon.com/images/I/71MDwv+VnSL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: Besides fleas and ticks does frontline plus kill ear mites ?** A: no **Q: The product ad says dogs 89 to 132lbs, but the description says 45-88lbs. My dogs are over 100lbs. Is this the correct product?** A: Where does it say it if for 45-88lbs? This items 'style' is 89-132lbs. This is what I get for my 3 dogs. One is 110lbs but the other two are 80lbs and 15lbs. I use a full dose for the large dog and split one for the other two. There are markings on the applicator to let you know how much you ha e used. The 15lb dog gets 1/4 dose and the 80lb dog get the remainder. It is much cheaper to buy the larger dosage and just distribute accordingly. **Q: How do you know the expiration date of this product?** A: FRONTLINE® Plus does not have an expiration date. **Q: Does Frontline have a strong odor when applied?** A: No. I never noticed an odor. ## Customer Reviews ### ⭐⭐⭐⭐⭐ This stuff still works great *by T***E on December 29, 2025* I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on Amazon! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more! ### ⭐⭐⭐⭐⭐ Still works in my part of the state *by S***H on September 23, 2024* Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away... ### ⭐⭐⭐⭐⭐ Works well on my dogs *by L***L on March 10, 2026* Great product, works well. ## Frequently Bought Together - Frontline Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 8 Treatments - Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments - Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 6 Doses --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.us/products/129475025-plus-flea-and-tick-spot-treatment-for-x-large-breed](https://www.desertcart.us/products/129475025-plus-flea-and-tick-spot-treatment-for-x-large-breed) --- *Product available on Desertcart United States of America* *Store origin: US* *Last updated: 2026-05-11*