---
product_id: 102389905
title: "THORNE - Riboflavin 5'-Phosphate - Bioactive Form of Vitamin B2 for Methylation Support* - 60 Capsules"
brand: "thorne"
price: "$65.98"
currency: USD
in_stock: true
reviews_count: 8
category: "Thorne"
url: https://www.desertcart.us/products/102389905-thorne-riboflavin-5-phosphate-bioactive-form-of-vitamin-b2-methylation
store_origin: US
region: United States of America
---

# Active B2 for instant bioavailability Free from gluten, dairy, soy & major allergens Supports healthy methylation pathways THORNE - Riboflavin 5'-Phosphate - Bioactive Form of Vitamin B2 for Methylation Support* - 60 Capsules

**Brand:** thorne
**Price:** $65.98
**Availability:** ✅ In Stock

## Summary

> 🧠 Elevate your wellness game with the bioactive B2 that champions trust!

## Quick Answers

- **What is this?** THORNE - Riboflavin 5'-Phosphate - Bioactive Form of Vitamin B2 for Methylation Support* - 60 Capsules by thorne
- **How much does it cost?** $65.98 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.us](https://www.desertcart.us/products/102389905-thorne-riboflavin-5-phosphate-bioactive-form-of-vitamin-b2-methylation)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Methylation Mastery:** Optimizes methylation processes critical for DNA repair, detox, and cardiovascular health.
- • **Allergen-Free Purity:** Crafted without gluten, dairy, soy, nuts, or shellfish—perfect for sensitive, health-conscious pros.
- • **Clinician-Trusted Formula:** Endorsed by 100+ pro sports teams and top healthcare practitioners for unmatched quality and efficacy.
- • **Holistic B Vitamin Synergy:** Supports formation of niacin and active B6, enhancing overall B-complex balance for metabolic resilience.
- • **Bioactive Vitamin B2 Powerhouse:** Riboflavin 5'-Phosphate form ensures rapid absorption and utilization for peak cellular energy.

## Overview

THORNE Riboflavin 5'-Phosphate delivers the bioactive form of Vitamin B2 designed for superior absorption and methylation support. Free from major allergens and trusted by elite athletes and healthcare professionals, this supplement enhances B vitamin synergy, supports healthy homocysteine levels, and promotes metabolic balance—ideal for millennials seeking cutting-edge, clean nutrition to optimize energy and cellular health.

## Description

Buy THORNE - Riboflavin 5'-Phosphate - Bioactive Form of Vitamin B2 for Methylation Support* - 60 Capsules on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Great product - Great product! I’ve been using almost a year!
Review: High Homocysteine, Hormones and the B2 Connection - This supplement has helped me in more ways than one. First it has helped me clear up Rosacea along with taking Olive Leaf extract. Whenever you take "extra amounts" of one of the B vitamins please be sure to also include a B complex. This supplement along with other active forms of the B vitamins has also helped me more so than taking the glandulars and herbs for Adrenal Fatigue. But most importantly this supplement helped with bringing down high homocysteine levels. I had high Homocysteine levels of 23 "after" starting on bio-identical hormones (progesterone) and I could not figure out why they would shoot up like that after starting on the hormones. I do not eat a lot of dairy and when a woman is pregnant the body requires more B2 (milk). B2 helps breaks down Folate acid and B12 when she is pregnant (or when she is taking progesterone) and if the body can not metabolize the B9 (Folate acid) and B12 it will raise Homocysteine levels which is really bad for your health. B6 also helps in keeping Homocysteine levels down but I think B2 is often overlooked in this process. For some reason the bio-identical doctor refused to make any connection with the high Homocysteine levels and the Hormone Replacement Therapy through email or on phone however after many hours of research and starting on the mega doses of the active forms of the B's (including this supplement by Thorne) I went back two months later to retest Homocysteine and they were down to 7.5. When I went back "in person" to talk to the bio-identical hormone doctor and showed him the new Homocysteine test after starting on on the B vitamins and presenting to him my theory on how the hormones "indirectly" caused a rise in Homocysteine by creating a deficiency in B2 when body thought it was pregnant by starting on the progesterone he sat back in his chair and said "you are correct" and in fact asked me for the "exact recipe" I used and wrote it down. My point here is the doctor was reluctant to discuss this via the phone or email, plus when I was asking him the question "what is the connection" he simply refused to even acknowledge there was one. It wasn't until I figured it out on my own and was in office "face to face" and with new blood work test in my hand that he acknowledge there was a connection between the rise in levels and starting the therapy. So the moral of the story is if you are a woman thinking about starting on bio-identical hormones make sure you are getting plenty of B2, B6 and Folate acid (note: the Methyl forms) and some B12 and have your B levels and Homocysteine levels tested "before" starting your treatments and then retesting them after being on the hormones. If you notice any increase or decrease in your B levels when you have not taken or changed any of your B vitamins from the time that you started the hormones to one month after being on them this is an indication of some change in a metabolic pathway that could lead to something very big like an increase in high Homocysteine levels. The problem can easily be fixed "if" you know about it but if left untreated can ultimately cause all kinds of unwanted health problems and contradict the whole purpose of the hormones. I am certainly not a doctor or giving medical advice, I am simply a concerned consumer sharing my personal experience in hopes that it may help someone else. In my opinion I would highly recommend this product if you are looking to bring down high Homocysteine levels, starting Bio-identical Progesterone, needing help with Adrenal fatigue or simply wanting to clear up Rosacea (for the Rosacea issue don't forget to add in Olive Leaf Extract) Good Luck and "thank you" THRONE!

## Features

- Active B2: The active form of vitamin B2 more readily used by the body*
- B Vitamin Formation: Important for the formation of other B vitamins, including niacin and active B6
- Methylation: Provides support for healthy methylation*
- Free From: Every Thorne product is made with the purest possible ingredients - without gluten or other major allergens (eggs, tree nuts, peanuts) This product also contains no soy, dairy, shellfish, or fish
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0797MLY4M |
| Age Range Description | Adult |
| Allergen Information | Dairy Free, Egg Free, Gluten Free, Peanut Free, Shellfish Free, Soy Free, Tree Nut Free |
| Best Sellers Rank | #13,553 in Health & Household ( See Top 100 in Health & Household ) #8 in Vitamin B2 (Riboflavin) Supplements |
| Brand | THORNE |
| Brand Name | THORNE |
| Customer Reviews | 4.7 out of 5 stars 528 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00693749115021 |
| Item Dimensions | 1.7 x 1.7 x 2.97 inches |
| Item Form | Capsule |
| Manufacturer | Thorne Research |
| Number of Items | 1 |
| Primary Supplement Type | Riboflavin |
| Product Benefits | Methylation |
| Specific Uses For Product | Digestive |
| UPC | 693749115021 |
| Unit Count | 60 Count |

## Product Details

- **Brand:** THORNE
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Capsule
- **Primary Supplement Type:** Riboflavin

## Images

![THORNE - Riboflavin 5'-Phosphate - Bioactive Form of Vitamin B2 for Methylation Support* - 60 Capsules - Image 1](https://m.media-amazon.com/images/I/716LDl1O29L.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Great product
*by C***C on January 20, 2026*

Great product! I’ve been using almost a year!

### ⭐⭐⭐⭐⭐ High Homocysteine, Hormones and the B2 Connection
*by L***7 on February 22, 2015*

This supplement has helped me in more ways than one. First it has helped me clear up Rosacea along with taking Olive Leaf extract. Whenever you take "extra amounts" of one of the B vitamins please be sure to also include a B complex. This supplement along with other active forms of the B vitamins has also helped me more so than taking the glandulars and herbs for Adrenal Fatigue. But most importantly this supplement helped with bringing down high homocysteine levels. I had high Homocysteine levels of 23 "after" starting on bio-identical hormones (progesterone) and I could not figure out why they would shoot up like that after starting on the hormones. I do not eat a lot of dairy and when a woman is pregnant the body requires more B2 (milk). B2 helps breaks down Folate acid and B12 when she is pregnant (or when she is taking progesterone) and if the body can not metabolize the B9 (Folate acid) and B12 it will raise Homocysteine levels which is really bad for your health. B6 also helps in keeping Homocysteine levels down but I think B2 is often overlooked in this process. For some reason the bio-identical doctor refused to make any connection with the high Homocysteine levels and the Hormone Replacement Therapy through email or on phone however after many hours of research and starting on the mega doses of the active forms of the B's (including this supplement by Thorne) I went back two months later to retest Homocysteine and they were down to 7.5. When I went back "in person" to talk to the bio-identical hormone doctor and showed him the new Homocysteine test after starting on on the B vitamins and presenting to him my theory on how the hormones "indirectly" caused a rise in Homocysteine by creating a deficiency in B2 when body thought it was pregnant by starting on the progesterone he sat back in his chair and said "you are correct" and in fact asked me for the "exact recipe" I used and wrote it down. My point here is the doctor was reluctant to discuss this via the phone or email, plus when I was asking him the question "what is the connection" he simply refused to even acknowledge there was one. It wasn't until I figured it out on my own and was in office "face to face" and with new blood work test in my hand that he acknowledge there was a connection between the rise in levels and starting the therapy. So the moral of the story is if you are a woman thinking about starting on bio-identical hormones make sure you are getting plenty of B2, B6 and Folate acid (note: the Methyl forms) and some B12 and have your B levels and Homocysteine levels tested "before" starting your treatments and then retesting them after being on the hormones. If you notice any increase or decrease in your B levels when you have not taken or changed any of your B vitamins from the time that you started the hormones to one month after being on them this is an indication of some change in a metabolic pathway that could lead to something very big like an increase in high Homocysteine levels. The problem can easily be fixed "if" you know about it but if left untreated can ultimately cause all kinds of unwanted health problems and contradict the whole purpose of the hormones. I am certainly not a doctor or giving medical advice, I am simply a concerned consumer sharing my personal experience in hopes that it may help someone else. In my opinion I would highly recommend this product if you are looking to bring down high Homocysteine levels, starting Bio-identical Progesterone, needing help with Adrenal fatigue or simply wanting to clear up Rosacea (for the Rosacea issue don't forget to add in Olive Leaf Extract) Good Luck and "thank you" THRONE!

### ⭐⭐⭐⭐⭐ The real deal, high quality
*by M***E on June 4, 2025*

I dump out the powder and titrate catered dosages for myself, and this powder works perfectly. Highly positive effects. Thank you for keeping such high quality standards during times of economic uncertainty.

## Frequently Bought Together

- THORNE Riboflavin 5'-Phosphate - Bioactive Form of Vitamin B2 for Methylation Support* - 60 Capsules
- THORNE Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Healthy Sleep & Methylation* - Gluten, Dairy & Soy-Free - 60 Capsules
- THORNE 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels* - 60 Capsules - 5-MTHF 1mg

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*Product available on Desertcart United States of America*
*Store origin: US*
*Last updated: 2026-02-28*